Calcium binding activity of the epidermal growth factor-like domains of the apicomplexan microneme protein EtMIC4

Molecular and Biochemical Parasitology

Volumn 143, Issue 2, 2005, Pages 192-199

  Periz, Javier ^a   Gill, Andrew C ^a   Knott, Vroni ^b   Handford, Penny A ^b   Tomley, Fiona M ^a  

^a INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Adhesion; Apicomplexa; Host cell invasion; Microneme; Motility

Indexed keywords

CALCIUM ION; EPIDERMAL GROWTH FACTOR; FIBRILLIN; MEMBRANE PROTEIN; MICRONEME PROTEIN 4; PROTOZOAL PROTEIN; UNCLASSIFIED DRUG;

APICOMPLEXA; ARTICLE; BINDING AFFINITY; BINDING SITE; CALCIUM BINDING; CIRCULAR DICHROISM; CONTROLLED STUDY; EIMERIA TENELLA; EUKARYOTIC CELL; EXTRACELLULAR CALCIUM; HOST CELL; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN INTERACTION; TANDEM REPEAT;

AMINO ACID SEQUENCE; ANIMALS; CALCIUM; CELL ADHESION MOLECULES; CIRCULAR DICHROISM; EIMERIA TENELLA; EPIDERMAL GROWTH FACTOR; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; PEPTIDE HYDROLASES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PROTOZOAN PROTEINS;

APICOMPLEXA; EIMERIA TENELLA; EUKARYOTA;

EID: 23944468221     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2005.06.003     Document Type: Article

References (23)

1. J.F. Dubremetz, N. Garcia-Reguet, V. Conseil, and M.N. Fourmaux Apical organelles and host-cell invasion by Apicomplexa Int J Parasitol 28 1998 1007 1013
2. V.B. Carruthers, O.K. Giddings, and L.D. Sibley Secretion of micronemal proteins is associated with toxoplasma invasion of host cells Cell Microbiol 1 1999 225 235
3. T.J. Jewett, and L.D. Sibley Aldolase forms a bridge between cell surface adhesins and the actin cytoskeleton in apicomplexan parasites Mol Cell 11 2003 885 894
4. C.A. Buscaglia, I. Coppens, W.G. Hol, and V. Nussenzweig Sites of interaction between aldolase and thrombospondin-related anonymous protein in plasmodium Mol Biol Cell 14 2003 4947 4957
5. I.D. Campbell, and P. Bork Epidermal growth factor-like modules Curr Opin Struct Biol 3 1993 385 392
6. M. Stacey, G.W. Chang, and J.Q. Davies The epidermal growth factor-like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans Blood 102 2003 2916 2924
7. A.K. Downing, V. Knott, J.M. Werner, C.M. Cardy, I.D. Campbell, and P.A. Handford Solution structure of a pair of calcium-binding epidermal growth factor-like domains: implications for the Marfan syndrome and other genetic disorders Cell 85 1996 597 605
8. F.M. Tomley, K.J. Billington, J.M. Bumstead, J.D. Clark, and P. Monaghan EtMIC4: a microneme protein from Eimeria tenella that contains tandem arrays of epidermal growth factor-like repeats and thrombospondin type-I repeats Int J Parasitol 31 2001 1303 1310
9. V. Knott, A.K. Downing, C.M. Cardy, and P. Handford Calcium binding properties of an epidermal growth factor-like domain pair from human fibrillin-1 J Mol Biol 255 1996 22 27
10. E.A. Raleigh, N.E. Murray, and H. Revel McrA and McrB restriction phenotypes of some E. coli strains and implications for gene cloning Nucleic Acids Res 16 1988 1563 1575
11. P.A. Handford, M. Baron, and M. Mayhew The first EGF-like domain from human factor IX contains a high-affinity calcium binding site Embo J 9 1990 475 480
12. R.S. Smallridge, P. Whiteman, K. Doering, P.A. Handford, and A.K. Downing EGF-like domain calcium affinity modulated by N-terminal domain linkage in human fibrillin-1 J Mol Biol 286 1999 661 668
13. P. Whiteman, R.S. Smallridge, V. Knott, J.J. Cordle, A.K. Downing, and P.A. Handford A G1127S change in calcium-binding epidermal growth factor-like domain 13 of human fibrillin-1 causes short range conformational effects J Biol Chem 276 2001 17156 17162
14. J.Y. Suk, S. Jensen, and A. McGettrick Structural consequences of cysteine substitutions C1997Y and C1997R in calcium-binding epidermal growth factor-like domain 30 of human fibrillin-1 J Biol Chem 279 2004 51258 51265
15. 2+ binding to EGF-like domains Protein Eng 5 6 1992 489 494
16. M. Stacey, H.H. Lin, K.L. Hilyard, S. Gordon, and A.J. McKnight Human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 is a new member of the EGF-TM7 family that recognizes a ligand on human macrophages and activated neutrophils J Biol Chem 276 22 2001 18863 18870
17. D.P. Reinhardt, R.N. Ono, and L.Y. Sakai Calcium stabilizes fibrillin-1 against proteolytic degradation J Biol Chem 272 2 1997 1231 1236
18. A.J. McGettrick, V. Knott, A. Willis, and P.A. Handford Molecular effects of calcium binding mutations in Marfan syndrome depend on domain context Hum Mol Genet 9 13 2000 1987 1994
19. C.M. Cardy, and P.A. Handford Metal ion dependency of microfibrils supports a rod-like conformation for fibrillin-1 calcium-binding epidermal growth factor-like domains J Mol Biol 276 5 1998 855 860
20. D.P. Reinhardt, D.E. Mechling, B.A. Boswell, D.R. Keene, L.Y. Sakai, and H.P. Bachinger Calcium determines the shape of fibrillin J Biol Chem 272 1997 7368 7373
21. J.M. Werner, V. Knott, P.A. Handford, I.D. Campbell, and A.K. Downing Backbone dynamics of a cbEGF domain pair in the presence of calcium J Mol Biol 296 2000 1065 1078
22. P.A. Handford, M. Mayhew, M. Baron, P.R. Winship, I.D. Campbell, and G.G. Brownlee Key residues involved in calcium-binding motifs in EGF-like domains Nature 351 1991 164 167
23. S.J. Davis, S. Ikemizu, M.K. Wild, and P.A. van der Merwe CD2 and the nature of protein interactions mediating cell-cell recognition Immunol Rev 163 1998 217 236