Poly(C) binding protein family is a transcription factor in μ-opioid receptor gene expression

Molecular Pharmacology

Volumn 68, Issue 3, 2005, Pages 729-736

  Kim, Sung Su ^a   Pandey, Krishan K ^a   Hack, Sun Choi ^a   Kim, Seong Youl ^a   Law, Ping Yee ^a   Wei, Li Na ^a   Loh, Horace H ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; DOUBLE STRANDED DNA; MU OPIATE RECEPTOR; OLIGONUCLEOTIDE; POLYCYTIDYLIC ACID; SINGLE STRANDED DNA; TRANSCRIPTION FACTOR;

ARTICLE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONTROLLED STUDY; DNA STRAND; DRUG PROTEIN BINDING; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MOLECULAR CLONING; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; RECEPTOR GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; BASE SEQUENCE; CARRIER PROTEINS; CELL LINE, TUMOR; CLONING, MOLECULAR; DNA PRIMERS; GENE EXPRESSION REGULATION; HUMANS; MICE; POLY C; PROMOTER REGIONS (GENETICS); RECEPTORS, OPIOID, MU; RNA, SMALL INTERFERING; TRANSCRIPTION FACTORS;

EID: 23944467312     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.105.012245     Document Type: Article

References (35)

1. Bausch SB, Patterson TA, Appleyard SM, and Chavkin C (1995) Immunocytochemical localization of delta opioid receptors in mouse brain. J Chem Neuroanat 8:175-189.
2. Bielinska A, Shivdasani RA, Zhang LQ, and Nabel GJ (1990) Regulation of gene expression with double-stranded phosphorothioate oligonucleotides. Science (Wash DC) 250:997-1000.
3. Chaillet P, Coulaud A, Zajac JM, Fournie-Zaluski MC, Costentin J, and Roques BP (1984) The mu rather than the delta subtype of opioid receptors appears to be involved in enkephalin-induced analgesia. Eur J Pharmacol 101:83-90.
4. Chen Y, Mestek A, Liu J, Hurley JA, and Yu L (1993) Molecular cloning and functional expression of a μ-opioid receptor from rat brain. Mol Pharmacol 44:8-12.
5. Collier B, Goobar-Larsson L, Sokolowski M, and Schwartz S (1998) Translational inhibition in vitro of human papillomavirus type 16 L2 mRNA mediated through interaction with heterogenous ribonucleoprotein K and poly(rC)-binding proteins 1 and 2. J Biol Chem 273:22648-22656.
6. Dejgaard K and Leffers H (1996) Characterisation of the nucleic-acid-binding activity of KH domains. Different properties of different domains. Eur J Biochem 241:425-431.
7. Greenberg ME and Bender TP (2002) Identification of Newly Transcribed RNA. John Wiley and Sons, New York.
8. Holcik M and Liebhaber SA (1997) Four highly stable eukaryotic mRNAs assemble 3′ untranslated region RNA-protein complexes sharing cis and trans components. Proc Natl Acad Sci USA 94:2410-2414.
9. Kieffer BL (1995) Recent advances in molecular recognition and signal transduction of active peptides: receptors for opioid peptides. Cell Mol Neurobiol 15:615-635.
10. Kieffer BL (1999) Opioids: first lessons from knockout mice. Trends Pharmacol Sci 20:19-26.
11. Kiledjian M, Wang X, and Liebhaber SA (1995) Identification of two KH domain proteins in the alpha-globin mRNP stability complex. EMBO (Eur Mol Biol Organ) J 14:4357-4364.
12. Kim CS, Hwang CK, Choi HS, Song KY, Law PY, Wei LN, and Loh HH (2004) Neuron-restrictive silencer factor (NRSF) functions as a repressor in neuronal cells to regulate the μ opioid receptor gene. J Biol Chem 279:46464-46473.
13. Ko JL, Liu HC, and Loh HH (2003) Role of an AP-2-like element in transcriptional regulation of mouse micro-opioid receptor gene. Brain Res Mol Brain Res 112:153-162.
14. Ko JL, Liu HC, Minnerath SR, and Loh HH (1998) Transcriptional regulation of mouse μ-opioid receptor gene. J Biol Chem 273:27678-27685.
15. Ko JL and Loh HH (2001) Single-stranded DNA-binding complex involved in transcriptional regulation of mouse μ-opioid receptor gene. J Biol Chem 276:788-795.
16. Ko JL and Loh HH (2005) Poly C binding protein, a single-stranded DNA binding protein, regulates mouse μ-opioid receptor gene expression. J Neurochem 93:749-761.
17. Ko JL, Minnerath SR, and Loh HH (1997) Dual promoters of mouse mu-opioid receptor gene. Biochem Biophys Res Commun 19:351-357.
18. Kraus J, Borner C, Giannini E, Hickfang K, Braun H, Mayer P, Hoehe MR, Ambrosch A, Konig W, and Hollt V (2001) Regulation of μ-opioid receptor gene transcription by interleukin-4 and influence of an allelic variation within a STAT6 transcription factor binding site. J Biol Chem 276:43901-43908.
19. Kraus J, Borner C, Giannini E, and Hollt V (2003) The role of nuclear factor κB in tumor necrosis factor-regulated transcription of the human μ-opioid receptor gene. Mol Pharmacol 64:876-884.
20. Law PY, Wong YH, and Loh HH (2000) Molecular mechanisms and regulation of opioid receptor signaling. Annu Rev Pharmacol Toxicol 40:389-430.
21. Leffers H, Dejgaard K, and Celis JE (1995) Characterisation of two major cellular poly(rC)-binding human proteins, each containing three K-homologous (KH) domains. Eur J Biochem 230:447-453.
22. Liang Y, Mestek A, Yu L, and Carr LG (1995) Cloning and characterization of the promoter region of the mouse mu opioid receptor gene. Brain Res 679:82-88.
23. Makeyev AV and Liebhaber SA (2000) Identification of two novel mammalian genes establishes a subfamily of KH-domain RNA-binding proteins. Genomics 67:301-316.
24. Makeyev AV and Liebhaber SA (2002) The poly(C)-binding proteins: a multiplicity of functions and a search for mechanisms. RNA 8:265-278.
25. Matunis MJ, Michael WM, and Dreyfuss G (1992) Characterization and primary structure of the poly(C)-binding heterogeneous nuclear ribonucleoprotein complex K protein. Mol Cell Biol 12:164-171.
26. Michelotti EF, Tomonaga T, Krutzsch H, and Levens D (1995) Cellular nucleic acid binding protein regulates the CT element of the human c-myc protooncogene. J Biol Chem 270:9494-9499.
27. Min BH, Augustin LB, Felsheim RF, Fuchs JA, and Loh HH (1994) Genomic structure analysis of promoter sequence of a mouse μ-opioid receptor gene. Proc Natl Acad Sci USA 91:9081-9085.
28. Minami M and Satoh M (1995) Molecular biology of the opioid receptors: structures, functions and distributions. Neurosci Res 23:121-145.
29. Ostareck DH, Ostareck-Lederer A, Wilm M, Thiele BJ, Mann M, and Hentze MW (1997) mRNA silencing in erythroid differentiation: hnRNP K and hnRNP E1 regulate 15-lipoxygenase translation from the 3′ end. Cell 89:597-606.
30. Pan YX (2002) Identification and characterization of a novel promoter of the mouse mu opioid receptor gene (Oprm) that generates eight splice variants. Gene 295:97-108.
31. Thompson RC, Mansour A, Akil H, and Watson SJ (1993) Cloning and pharmacological characterization of a rat mu opioid receptor. Neuron 11:903-913.
32. Waggoner SA and Liebhaber SA (2003) Identification of mRNAs associated with alphaCP2-containing RNP complexes. Mol Cell Biol 23:7055-7067.
33. Wang JB, Imai Y, Eppler CM, Gregor P, Spivak CE, and Uhl GR (1993) μ Opiate receptor: cDNA cloning and expression. Proc Natl Acad Sci USA 90:10230-10234.
34. Weiss IM and Liebhaber SA (1995) Erythroid cell-specific mRNA stability elements in the alpha 2-globin 3′ nontranslated region. Mol Cell Biol 15:2457-2465.
35. Zhang Y and Dufau ML (2002) Silencing of transcription of the human luteinizing hormone receptor gene by histone deacetylase-mSin3A complex. J Biol Chem 277:33431-33438.