Evaluation of the stability of chlortetracycline in granular premixes by monitoring its conversion into degradation products

Journal of Pharmaceutical and Biomedical Analysis

Volumn 39, Issue 3-4, 2005, Pages 523-530

  Diana, J ^a   Vandenbosch, L ^a   De Spiegeleer, B ^b   Hoogmartens, J ^a   Adams, E ^a  

^a DEPARTMENT OF PHARMACEUTICAL AND PHARMACOLOGICAL SCIENCES   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

Chlortetracycline; Degradation products; LC; Premixes; Stability

Indexed keywords

4 EPIANHYDROCHLORTETRACYCLINE; 4 EPICHLORTETRACYCLINE; 4 EPIISOCHLORTETRACYCLINE; 4 EPINORCHLORTETRACYCLINE; ANHYDROCHLORTETRACYCLINE; ANTIBIOTIC AGENT; CHLORTETRACYCLINE; DEMECLOCYCLINE; DRUG METABOLITE; EPITETRACYCLINE; ISOCHLORTETRACYCLINE; SOLVENT; TETRACYCLINE; UNCLASSIFIED DRUG;

ACIDIFICATION; ARTICLE; COLUMN; DEVICE; DRUG FORMULATION; DRUG GRANULE; DRUG IMPURITY; DRUG ISOLATION; DRUG MONITORING; DRUG STABILITY; ELUTION; LIQUID CHROMATOGRAPHY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SEPARATION TECHNIQUE;

ANTI-BACTERIAL AGENTS; CHEMISTRY, PHARMACEUTICAL; CHLORTETRACYCLINE; CHROMATOGRAPHY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; DRUG INDUSTRY; DRUG STABILITY; MODELS, CHEMICAL; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SOLVENTS; TIME FACTORS;

EID: 23944457109     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2005.04.030     Document Type: Article

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