The transition to the metastatic phenotype of rat lymphoma cells involves up-regulation of IL-10 receptor expression and IL-10 secretion

Clinical and Experimental Metastasis

Volumn 22, Issue 2, 2005, Pages 127-135

  Rico, María José ^a   Matar, Pablo ^a   Gervasoni, Silvia I ^a   Bonfil, R Daniel ^b   Calcaterra, Nora ^c   Scharovsky, O Graciela ^a  

^a FACULTAD DE CIENCIAS MÉDICAS   (Argentina)

^b WAYNE STATE UNIVERSITY   (United States)

^c Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

Author keywords

IL 10; IL 10R; Lymphoma; Malignant phenotype; Metastasis

Indexed keywords

CYTOKINE; GROWTH FACTOR; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR; MESSENGER RNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; B CELL LYMPHOMA; CELL TYPE; CONTROLLED STUDY; CYTOKINE RELEASE; GENE EXPRESSION; IMMUNE DEFICIENCY; IMMUNE RESPONSE; IMMUNOREGULATION; LYMPHOMA CELL; METASTASIS; NONHUMAN; PHENOTYPE; PROTEIN BINDING; PROTEIN EXPRESSION; RAT; TH2 CELL; UPREGULATION;

ANIMALS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; INTERLEUKIN-10; LYMPHOMA, B-CELL; NEOPLASM METASTASIS; PHENOTYPE; RATS; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-10; RNA, MESSENGER; UP-REGULATION;

EID: 23944457065     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10585-005-5140-4     Document Type: Article

References (37)

1. MC Cohen S. Cohen 1996 Cytokine function. A study in biologic diversity Am J Clin Pathol 105 589 98
2. R De Waal Malefyt J Haanen H Spits 1991 Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II Major Histocompatibility Complex expression J Exp Med 174 915 24
3. R Donnelly H Dickensheets D. Finbloom 1999 The interleukin-10 signal transduction pathway and regulation of gene expression in mononuclear phagocytes J Interferon Cytokine Res 19 563 73
4. S Mocellin F Marincola CR Rossi 2004 The multifaceted relationship between IL-10 and adaptative immunity: putting together the pieces of a puzzle Cytokine Growth Factor Rev 15 61 76
5. L Ding P Linsley L Huang 1993 E. IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression J Immunol 151 1224 34
6. M Howard A. O'Garra 1992 Biological properties of interleukin 10 Immunol Today 13 6 198 200
7. Q Chen V Daniel D Maher P. Hersey 1994 Production of IL-10 by melanoma cells: examination of its role in immunosuppression mediated by melanoma Int J Cancer 56 755 60
8. S Chouaib C Asselin-Paturel F Mami-Chouaib 1997 The host-tumor immune conflict: from immunosuppession to resistance and destruction Immunol Today 18 493 7
9. G. Pawelec 1999 Tumour escape from the immune response the last hurdle for successful immunotherapy of cancer? Cancer Immunol Immunother 48 343 5
10. P Matar VR Rozados AD González 2000 Mechanism of antimetastatic immunopotentiation by low-dose cyclophosphamide Eur J Cancer 36 1060 6
11. P Matar VR Rozados SI Gervasoni OG. Scharovsky 2001 Down regulation of T-Cell-derived IL-10 production by low-dose cyclophosphamide treatment in tumor-bearing rats restores in vitro normal proliferative response Int Immunopharmacol 1 307 19
12. P Matar VR Rozados SI Gervasoni OG. Scharovsky 2002 Th2/Thl switch induced by a single low dose of cyclophosphamide in a rat metastatic lymphoma model Cancer Immunol Immunother 50 588 96
13. JY Blay N Burdin F Rousset 1993 Serum interleukin-10 in non-Hodgkin's lymphoma a prognostic factor Blood 82 2169 74
14. H Ward S Vigues S Poole AF. Bristow 2001 The rat interleukin 10 receptor: cloning and sequencing of cDNA coding for the alpha-chain protein sequence, and demonstration by western blotting of expression in the rat brain Cytokine 15 237 40
15. S Calderari MT Font O Garrocq 1991 The inbred IIM/Fm stock Rat News Lett 25 28 9
16. Canadian Council on Animal Care Guide to the Care and Use of Experimental Animals Vol 1, 2nd edn, 1993
17. MT Font GC Celoria LI. Hinrichsen 1983 Genetic analysis of tumor resistance in an inbred line of rats Medicina (B Aires) 43 502 8
18. KW Walker R Llul GK Balkian 1992 A rapid sensitive cellular enzyme-linked immunoadsorbent assay (CELISA) for the detection and quantitation of antibodies against cell surface determinants J Immunol Methods 154 121 30
19. -ΔΔCt method Methods 25 402 8
20. JJ Sedmak SE. Grossberg 1977 A rapid, sensitive and versatile assay for protein using Coomassie brilliant blue G250 Anal Biochem 79 544 52
21. UK. Laemmli 1970 Cleavage of structural protein during the assembly of the head of bacteriophage T4 Nature 227 680 5
22. R. Welch Danny 2003 Metastasis regulatory genes Sci Med 9 202 13
23. R Kiessling K Wasserman S Horiguchi 1999 Tumor-induced immune dysfunction Cancer Immunol Immunother 48 353 62
24. RD Bonfil GA López R Fridman 2002 Biología de la invasión y las metastasis RD Bonfil OG Scharovsky Oncología Molecular y Celular Editorial Dunken Buenos Aires 245 64
25. E. Gilboa 1999 How tumors escape immune destruction and what we can do about it Cancer Immunol Immunother 48 382 5
26. TR Mosmann RL. Coffman 1989 Th1 and Th2 cells: Different patterns of lymphokine secretion lead to different functional properties Ann Rev Immunol 7 145 73
27. H Bohlen M Kessler M Sextro 2000 Poor clinical outcome of patients with Hodgkin's disease and elevated interleukin-10 serum levels Ann Hematol 79 110 3
28. J Kim RL Modlin RL Moy 1995 IL-10 production in cutaneous basal and squamous cell carcinomas. A mechanism for evading the local T cell immune response J Immunol 155 2240 7
29. FY Yue R Dummer R Geertsen 1997 Interleukin-10 is a growth factor for human melanoma cells and down-regulates HLA class-I, HLA class-II and ICAM-I molecules Int J Cancer 71 630 7
30. M Kobayashi H Kobayashi RB Pollard F. Suzuki 1998 A pathogenic role of Th2 cells and their cytokine products on the pulmonary metastasis of murine B16 melanoma J Immunol 160 5869 73
31. F De Vita M Orditura G Galizia 2000 Serum interleukin-10 levels as a prognostic factor' in advanced non-small cell lung cancer patients Chest 117 365 73
32. M Huang J Wang P Lee 1995 Human non-small cell lung cancer express a type 2 cytokine pattern Cancer Res 55 3847 53
33. GL. Nicolson 1993 Cancer progression and growth: Relationship of paracrine and autocrine growth mechanisms to organ preference of metastasis Exp Cell Res 204 171 80
34. IJ Fidler 1997 Molecular biology of cancer. Invasion and metastasis F De Vita T Vincent S Hellman SA Rosenberg Cancer Principles and Practice of Oncology. 5th edition. Lippincott-Raven Publishers Philadelphia 121 34
35. O Nyormoi M. Bar-Eli 2003 Transcriptional regulation of metastasis-related genes in human melanoma Clin Exp Metastasis 30 251 63
36. M Salerno T Ouatas D Palmieri PS. Steeg 2003 Inhibition of signal transduction by nm23 metastasis suppressor: possible mechanisms Clin Exp Metastasis 20 3 10
37. J Hamada PG Cavanaugh O Lotan GL. Nicolson 1992 Separable growth and migration factors for large-cell lymphoma cells secreted by microvascular endotelial cells derived from target organs for metastasis Br J Cancer 6 349 54