Biodistribution and excretion of radioactivity after the administration of 166Ho-chitosan complex (DW-166HC) into the prostate of rat

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 32, Issue 8, 2005, Pages 910-917

  Seung, Kyoo Seong ^a   Jei, Man Ryu ^a   Dong, Hyuk Shin ^a   Eun, Jeong Bae ^a   Shigematsu, Akiyo ^b   Hatori, Yasuhiko ^b   Nishigaki, Junko ^b   Kwak, Cheol ^c   Sang, Eun Lee ^c   Kyong, Bae Park ^d  

^a DongWha Pharm Ind Co   (South Korea)

^b Institute of Whole Body Metabolism   (Japan)

^c Seoul National University Hospital   (South Korea)

^d Korea Atomic Energy Research Institute   (South Korea)

Author keywords

DW 166HC; Intraprostatically; Prostate cancer

Indexed keywords

HOLMIUM NITRATE CHITOSAN HO 166; HOLMIUM NITRATE HO 166; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG EXCRETION; DRUG HALF LIFE; FECES ANALYSIS; KIDNEY; LIVER; MALE; NONHUMAN; PROSTATE; RADIOACTIVITY; RAT; SPLEEN; TISSUE LEVEL; WHOLE BODY AUTORADIOGRAPHY;

ANIMALS; BODY BURDEN; CHITIN; DRUG EVALUATION, PRECLINICAL; FECES; HOLMIUM; INJECTIONS; MALE; METABOLIC CLEARANCE RATE; ORGAN SPECIFICITY; ORGANOMETALLIC COMPOUNDS; PROSTATE; RADIATION DOSAGE; RADIOISOTOPES; RADIOMETRY; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION; WHOLE-BODY COUNTING;

EID: 23944452412     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-005-1792-1     Document Type: Article

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