-
1
-
-
0029559927
-
Molecular mechanisms of immunosuppression by cyclosporine, FK506, and rapamycin
-
Cardenas ME, Zhu D, Heitman J. Molecular mechanisms of immunosuppression by cyclosporine, FK506, and rapamycin. Curr Opin Nephrol Hypertens 1995; 4:472.
-
(1995)
Curr Opin Nephrol Hypertens
, vol.4
, pp. 472
-
-
Cardenas, M.E.1
Zhu, D.2
Heitman, J.3
-
2
-
-
0026768730
-
The immunosuppressive and toxic effects of FK-506 are mechanistically related: Pharmacology of a novel antagonist of FK-506 and rapamycin
-
Dumont FJ, Staruch MJ, Koprak SL, et al. The immunosuppressive and toxic effects of FK-506 are mechanistically related: pharmacology of a novel antagonist of FK-506 and rapamycin. J Exp Med 1992; 176:751.
-
(1992)
J Exp Med
, vol.176
, pp. 751
-
-
Dumont, F.J.1
Staruch, M.J.2
Koprak, S.L.3
-
3
-
-
0031813980
-
The side-effects of ciclosporine-A and tacrolimus
-
Mihatsch MJ, Kyo M, Morozumi K, Yamaguchi Y, Nickeleit V, Ryffel B. The side-effects of ciclosporine-A and tacrolimus. Clin Nephrol 1998; 49:356.
-
(1998)
Clin Nephrol
, vol.49
, pp. 356
-
-
Mihatsch, M.J.1
Kyo, M.2
Morozumi, K.3
Yamaguchi, Y.4
Nickeleit, V.5
Ryffel, B.6
-
4
-
-
0026019181
-
Is cyclophilin involved in the immunosuppressive and nephrotoxic mechanism of action of cyclosporin A?
-
Sigal NH, Dumont F, Durette P et al. Is cyclophilin involved in the immunosuppressive and nephrotoxic mechanism of action of cyclosporin A? J Exp Med 1991; 173:619.
-
(1991)
J Exp Med
, vol.173
, pp. 619
-
-
Sigal, N.H.1
Dumont, F.2
Durette, P.3
-
5
-
-
0032213194
-
Chronic rejection and chronic cyclosporin toxicity in renal allografts
-
Pascual M, Swinford RD, Ingelfinger JR, et al. Chronic rejection and chronic cyclosporin toxicity in renal allografts. Immunol Today 1998; 19:514.
-
(1998)
Immunol Today
, vol.19
, pp. 514
-
-
Pascual, M.1
Swinford, R.D.2
Ingelfinger, J.R.3
-
6
-
-
0032949981
-
Evaluation of individual and combined neurotoxicity of the immunosuppressants cyclosporine and sirolimus by in vitro multinuclear NMR spectroscopy
-
Serkova N, Litt L, James TL, et al. Evaluation of individual and combined neurotoxicity of the immunosuppressants cyclosporine and sirolimus by in vitro multinuclear NMR spectroscopy. J Pharmacol Exp Ther 1999; 289:800.
-
(1999)
J Pharmacol Exp Ther
, vol.289
, pp. 800
-
-
Serkova, N.1
Litt, L.2
James, T.L.3
-
7
-
-
0033966044
-
The novel immunosuppressant SDZ-RAD protects rat brain slices from cyclosporine-induced reduction of high-energy phosphates
-
Serkova N, Litt L, Leibfritz D et al. The novel immunosuppressant SDZ-RAD protects rat brain slices from cyclosporine-induced reduction of high-energy phosphates. Br J Pharmacol 2000; 129:485.
-
(2000)
Br J Pharmacol
, vol.129
, pp. 485
-
-
Serkova, N.1
Litt, L.2
Leibfritz, D.3
-
9
-
-
0035400375
-
Flow cytometric quantitation of calcium-dependent and -independent mitogen-stimulation of T cell functions in whole blood: Inhibition by immunosuppressive drugs in vitro
-
Barten MJ, Gummert JF, van Gelder T, Shorthouse R, Morris RE. Flow cytometric quantitation of calcium-dependent and -independent mitogen-stimulation of T cell functions in whole blood: inhibition by immunosuppressive drugs in vitro. J Immunol Methods 2001; 253:95.
-
(2001)
J Immunol Methods
, vol.253
, pp. 95
-
-
Barten, M.J.1
Gummert, J.F.2
Van Gelder, T.3
Shorthouse, R.4
Morris, R.E.5
-
10
-
-
0034667746
-
Pharmacodynamics of mycophenolic acid in heart allograft recipients: Correlation of lymphocyte proliferation and activation with pharmacokinetics and graft histology
-
Gummert JF, Barten MJ, van Gelder T, Billingham ME, Morris RE. Pharmacodynamics of mycophenolic acid in heart allograft recipients: correlation of lymphocyte proliferation and activation with pharmacokinetics and graft histology. Transplantation 2000; 70:1038.
-
(2000)
Transplantation
, vol.70
, pp. 1038
-
-
Gummert, J.F.1
Barten, M.J.2
Van Gelder, T.3
Billingham, M.E.4
Morris, R.E.5
-
11
-
-
0026503434
-
Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A
-
Fruman DA, Klee CB, Bierer BE, Burakoff SJ. Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A. Proc Natl Acad Sci U S A 1992; 89:3686.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 3686
-
-
Fruman, D.A.1
Klee, C.B.2
Bierer, B.E.3
Burakoff, S.J.4
-
12
-
-
0028998848
-
Targets of immunophilin-immunosuppressant complexes are distinct highly conserved regions of calcineurin A
-
Cardenas ME, Muir RS, Breuder T, Heitman J. Targets of immunophilin-immunosuppressant complexes are distinct highly conserved regions of calcineurin A. EMBO J 1995; 14:2772.
-
(1995)
EMBO J
, vol.14
, pp. 2772
-
-
Cardenas, M.E.1
Muir, R.S.2
Breuder, T.3
Heitman, J.4
-
13
-
-
0029064172
-
Interaction of FKBP12-FK506 with calcineurin A at the B subunit-binding domain
-
Kawamura A, Su MS. Interaction of FKBP12-FK506 with calcineurin A at the B subunit-binding domain. J Biol Chem 1995; 270:15463.
-
(1995)
J Biol Chem
, vol.270
, pp. 15463
-
-
Kawamura, A.1
Su, M.S.2
-
14
-
-
0028090570
-
The latch region of calcineurin B is involved in both immunosuppressant-immunophilin complex docking and phosphatase activation
-
Milan D, Griffith J, Su M, Price ER, McKeon F. The latch region of calcineurin B is involved in both immunosuppressant-immunophilin complex docking and phosphatase activation. Cell 1994; 79:437.
-
(1994)
Cell
, vol.79
, pp. 437
-
-
Milan, D.1
Griffith, J.2
Su, M.3
Price, E.R.4
McKeon, F.5
-
15
-
-
0034721108
-
Immunophilins may limit calcineurin inhibition by cyclosporine and tacrolimus at high drug concentrations
-
Kung L, Halloran PF. Immunophilins may limit calcineurin inhibition by cyclosporine and tacrolimus at high drug concentrations. Transplantation 2000; 70:327.
-
(2000)
Transplantation
, vol.70
, pp. 327
-
-
Kung, L.1
Halloran, P.F.2
-
16
-
-
0031575750
-
Tissue distribution and abundance of human FKBP51, and FK506-binding protein that can mediate calcineurin inhibition
-
Baughman G, Wiederrecht GJ, Chang F, Martin MM, Bourgeois S. Tissue distribution and abundance of human FKBP51, and FK506-binding protein that can mediate calcineurin inhibition. Biochem Biophys Res Commun 1997; 232:437.
-
(1997)
Biochem Biophys Res Commun
, vol.232
, pp. 437
-
-
Baughman, G.1
Wiederrecht, G.J.2
Chang, F.3
Martin, M.M.4
Bourgeois, S.5
-
17
-
-
0027323876
-
Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: Roles of calcineurin binding and cellular location
-
Bram RJ, Hung DT, Martin PK, Schreiber SL, Crabtree GR. Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: roles of calcineurin binding and cellular location. Mol Cell Biol 1993; 13:4760.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 4760
-
-
Bram, R.J.1
Hung, D.T.2
Martin, P.K.3
Schreiber, S.L.4
Crabtree, G.R.5
-
18
-
-
0027267916
-
Localization of the FK506-binding protein, FKBP 13, to the lumen of the endoplasmic reticulum
-
Nigam SK, Jin YJ, Jin MJ, Bush KT, Bierer BE, Burakoff SJ. Localization of the FK506-binding protein, FKBP 13, to the lumen of the endoplasmic reticulum. Biochem J 1993; 294: 511.
-
(1993)
Biochem J
, vol.294
, pp. 511
-
-
Nigam, S.K.1
Jin, Y.J.2
Jin, M.J.3
Bush, K.T.4
Bierer, B.E.5
Burakoff, S.J.6
-
19
-
-
0027956811
-
Inhibition of calcineurin by a novel FK-506-binding protein
-
Sewell TJ, Lam E, Martin MM, et al. Inhibition of calcineurin by a novel FK-506-binding protein. J Biol Chem 1994; 269:21094.
-
(1994)
J Biol Chem
, vol.269
, pp. 21094
-
-
Sewell, T.J.1
Lam, E.2
Martin, M.M.3
-
20
-
-
0031457622
-
Signaling through scaffold, anchoring, and adaptor proteins
-
Pawson T, Scott JD. Signaling through scaffold, anchoring, and adaptor proteins. Science 1997; 278:2075.
-
(1997)
Science
, vol.278
, pp. 2075
-
-
Pawson, T.1
Scott, J.D.2
|