Long-term remission after 1 course of 12 weeks of alefacept therapy - A case report

Dermatology

Volumn 211, Issue 2, 2005, Pages 165-166

  Vitéz, Lilla ^a   Heese, Elisabeth ^a   Wozel, Gottfried ^a  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

Author keywords

Alefacept; Biologic agents; Immunomodulation; Psoriasis; Systemic therapy

Indexed keywords

ALEFACEPT; CALCIPOTRIOL;

ADULT; CASE REPORT; CLINICAL FEATURE; DISEASE COURSE; FEMALE; FOLLOW UP; HUMAN; LABORATORY TEST; LETTER; PHYSICAL EXAMINATION; PRIORITY JOURNAL; PSORIASIS; REMISSION;

DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; FOLLOW-UP STUDIES; HUMANS; INJECTIONS, INTRAMUSCULAR; MIDDLE AGED; PATIENT SATISFACTION; PSORIASIS; RECOMBINANT FUSION PROTEINS; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 23844548664     PISSN: 10188665     EISSN: None     Source Type: Journal    
DOI: 10.1159/000086451     Document Type: Letter

References (6)

1. Ellis CN, Krueger G: Treatment of chronic plaque psoriasis by selective targeting of memory effector T lymphocytes. N Engl J Med 2001;345:248-255.
2. Krueger GG, Callis KP: Development and use of alefacept to treat psoriasis. J Am Acad Dermatol 2003;49(suppl 2):S87-S97.
3. Krueger GG, Papp KA, Stough DB, Loven KH, Gulliver WP, Ellis CN: A randomized, double-blind, placebo-controlled phase III study evaluating efficacy and tolerability of 2 courses of alefacept in patients with chronic plaque psoriasis. J Am Acad Dermatol 2002;47:821-833.
4. Lebwohl M, Christophers E, Langley R, Ortonne JP, Roberts J, Griffiths CE, Alefacept Clinical Study Group: An international, randomized, double-blind, placebo-controlled phase 3 trial of intramuscular alefacept in patients with chronic plaque psoriasis. Arch Dermatol 2003;139:719-727.
5. Gordon KB, Langley RG: Remittive effects of intramuscular alefacept in psoriasis. J Drugs Dermatol 2003;2:624-628.
6. Gordon KB, Vaishnaw AK, O'Gorman J, Haney J, Menter A, Alefacept Clinical Study Group: Treatment of psoriasis with alefacept: Correlation of clinical improvement with reductions of memory T-cell counts. Arch Dermatol 2003;139:1563-1570.