Patch clamped single pancreatic zymogen granules: Direct measurements of ion channel activities at the granule membrane

Pancreatology

Volumn 5, Issue 4-5, 2005, Pages 443-449

  Kelly, Marie L ^a   Abu Hamdah, Rania ^a   Jeremic, Aleksandar ^a   Cho, Sang Joon ^a   Ilie, Alina Elena ^a   Jena, Bhanu P ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Ion channels; Patch clamp; Single secretory vesicle

Indexed keywords

4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; CHLORIDE CHANNEL; GLIBENCLAMIDE; ION CHANNEL; POTASSIUM CHANNEL; QUININE; ZYMOGEN GRANULE;

ACINAR CELL; ANIMAL CELL; ARTICLE; CELL MEMBRANE; ELECTRIC CURRENT; MALE; MEMBRANE CHANNEL; MEMBRANE CURRENT; NONHUMAN; PANCREAS; PRIORITY JOURNAL; RAT; SECRETORY VESICLE;

EID: 23844544778     PISSN: 14243903     EISSN: 14243911     Source Type: Journal    
DOI: 10.1159/000086556     Document Type: Article

References (28)

1. Jena BP: Discovery of the porosome: Revealing the molecular mechanism of secretion and membrane fusion in cells. J Cell Molec Med 2004;8:1-21.
2. Jena BP, Schneider SW, Geibel JP, Webster P, Oberleithner H, Sritharan KC: Gi regulation of secretory vesicle swelling examined by atomic force microscopy. Proc Natl Acad Sci USA 1997;94:13317-13322.
3. Cho S J, Sattar AK, Jeong EH, Satchi M, Cho JA, Dash S, Mayes MS, Stromer MH, Jena BP: Aquaporin 1 regulates GTP-induced rapid gating of water in secretory vesicles. Proc Natl Acad Sci USA 2002;99:4720-4724.
4. Abu-Hamdah R, Cho WJ, Cho SJ, Jeremic A, Kelly M, Ilie AE, Jena BP: Regulation of the water channel aquaporin-1: Isolation and reconstruction of the regulatory complex. Cell Biol Int 2004;28:7-17.
5. El Far O, Betz H: Synaptophysins: Vesicular cation channels? J Physiol 2002;1:539(Pt 2): 332.
6. Thevenod F: Ion channels in secretory granules of the pancreas and their role in exocytosis and release of secretory proteins. Am J Physiol Cell Physiol 2002;283:C651-C672.
7. - channel activation in secretory cells. Ann Rev Physiol 2000;62:493-513.
8. Thevenod F, Braun M, Roussa E, Fuller CM: Molecular characterisation of pancreatic zymogen granule ion channel and regulator proteins involved in exocytosis. J Korean Med Sci 2000;15(suppl):S51-S52.
9. +-selective conductance. Mol Pharmacol 2000;57:308-316.
10. Thevenod F, Hildebrandt JP, Striessnig J, de Jonge HR, Schulz I: Chloride and potassium conductances of mouse pancreatic zymogen granules are inversely regulated by a approx 80-kDa mdrla gene product. J Biol Chem 1996;271:3300-3305.
11. Kicinska A, Debska G, Szewczyk A: Intracellular ion channels: Properties, function and experimental methodology (in Polish). Postepy Hig Med Dosw 2000;54:307-316.
12. Cho SJ, Kelly M, Rognlien KT, Cho J-A, Horber JKH, Jena BP: SNAREs in opposing bilayers interact in a circular array to form conducting pores. Biophys J 2002;23:2522-2527.
13. Rahamimoff R, Butkevich A, Duridanova D, Ahdut R, Harari E, Kachalsky SG: Multitude of ion channels in the regulation of transmitter release. Phil Trans R Soc London B 1999;354:281-288.
14. Kelly ML, Woodbury DJ: Ion channels from synaptic vesicle membrane fragments reconstituted into lipid bilayers. Biophys J 1996;70:2593-2599.
15. Woodbury DJ: Evaluation of the evidence for ion channels in synaptic vesicles. Mol Memb Biol 1995;12:165-171.
16. Yakir N, Rahamimoff R: The non-specific ion channel in Torpedo ocellata fused synaptic vesicles. J Physiol 1995;485(Pt 3):683-697.
17. Kopelman H, Gauthier C: Cyclic AMP-sensitive chloride efflux in rabbit pancreatic acini. Pediatric Res 1999;29:529-533.
18. Spruce AE, Breckenridge LJ, Lee AK, Almers W: Properties of the fusion pore that forms during exocytosis of a mast cell secretory vesicle. Neuron 1990;4:643-654.
19. Rahamimoff R, Deriemer SA, Ginsburg S, Kaiserman I, Sakmann B, Shapira R, Stadler H, Yakir N: Ionic channels in synaptic vesicles: Are they involved in transmitter release? J Exp Physiol 1989;74:1019-1031.
20. Stanley EF, Ehrenstein G, Russell GT: Evidence for anion channels in secretory vesicles. Neuroscience 1988;25:1035-1039.
21. Horber JKH, Mosbacher J, Haberle W, Ruppersberg JP, Sakmann B: A look at membrane patches with a scanning force microscope. Biophys J 1995;68:1687-1693.
22. Anthony TL, Brooks HL, Boassa D, Leonov S, Yanochko G, Regan JW, Yool AJ: Cloned Human Aquaporin-1 Is a Cyclic GMP-Gated Ion Channel. Mol Pharmacol 2000;57:576-588.
23. Brooks HL, Regan JW, Yool AJ: Inhibition of aquaporin-1 water permeability by tetraethyl-ammonium: Involvement of the loop E pore region. Mol Pharmacol 2000;57:1021-1026.
24. Saparov SM, Kozono D, Rothe U, Agre P, Pohl P: Water and ion permeation of aquaporin-1 in planar lipid bilayers. J Biol Chem 2001;276:31515-31520.
25. Yool AJ, Weinstein AM: New roles for old holes: Ion channel function in aquaporin-1. News Physiol Sci 2002;17:68-72.
26. Carew MAC, Thorn P: Identification of CLC-2 like chloride currents in pig pancreatic acinar cells. Pflugers Archiv 1996;433:84-90.
27. Al-Awqati Q: Chloride channels of intracellular organelles. Curr Opin Cell Biol 1995;7:504-508.
28. Szewczyk A: The intracellular potassium and chloride channels: Properties, pharmacology and function. Mol Memb Biol 1998;15:49-58.