Mutations in the desat1 gene reduces the production of courtship stimulatory pheromones through a marked effect on fatty acids in Drosophila melanogaster

Insect Biochemistry and Molecular Biology

Volumn 35, Issue 8, 2005, Pages 911-920

  Ueyama, Morio ^a   Chertemps, Thomas ^a   Labeur, Carole ^a   Wicker Thomas, Claude ^a  

^a CNRS   (France)

Author keywords

Courtship; Desat1; Drosophila; Fatty acids; Hydrocarbons; mRNA quantification

Indexed keywords

DROSOPHILA MELANOGASTER; VERTEBRATA;

ACYL COENZYME A DESATURASE; DROSOPHILA PROTEIN; FATTY ACID; SEX PHEROMONE;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL LINE; COURTSHIP; DROSOPHILA MELANOGASTER; FEMALE; GENETICS; MALE; METABOLISM; MUTATION; PHYSIOLOGY;

ANIMALS; CELL LINE; COURTSHIP; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FATTY ACID DESATURASES; FATTY ACIDS; FEMALE; MALE; MUTATION; SEX ATTRACTANTS;

EID: 23844528580     PISSN: 09651748     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ibmb.2005.03.007     Document Type: Article

References (32)

1. Antony, C., Davis, T.L., Carlson, D.A., Péchiné, J.M., Jallon, J.M., 1985. Compared behavioral responses of male Drosophila melanogaster (Canton S) to natural and synthetic aphrodisiacs. J. Chem. Ecol. 11, 1617-1629.
2. Bartelt, R.J., Schaner, A.M., Jackson, L.L., 1985. Cis-vaccenyl acetate as an aggregation pheromone in Drosophila melanogaster. J. Chem. Ecol. 11, 1744-1756.
3. Buser, H.R., Arn, H., Guerin, P., Rauscher, S., 1983. Determination of double bond position in mono-unsaturated acetates by mass spectrometry of dimethyl disulfide adducts. Anal. Chem. 55, 818-822.
4. Butterworth, F.M., 1969. Lipids of Drosophila; a new detected lipid in the male. Science 163, 1256-1257.
5. Dallerac, R., Labeur, C., Jallon, J.M., Knipple, D.C., Roelofs, W.L., Wicker-Thomas, C., 2000. A Δ9 desaturase gene with a different substrate specificity is responsible for the cuticular diene hydrocarbon polymorphism in Drosophila melanogaster. Proc. Nat. Acad. Sci. USA 97, 9449-9454.
6. Dunkelblum, E., Tan, S.H., Silk, P.J., 1985. Double-bond location in monounsaturated fatty acids by dimethyl disulfide derivatization and mass spectrometry: application to analysis of fatty acids in pheromone glands of four lepidoptera. J. Chem. Ecol. 11, 265-277.
7. Ferveur, J.F., Sureau, G., 1996. Simultaneous influence on male courtship of stimulatory and inhibitory pheromones produced by live sex mosaic Drosophila melanogaster. Proc. Roy. Soc. London B 263, 967-973.
8. Geer, B.W., Perille, T.J., 1977. Effects of dietary sucrose and environmental temperature on fatty acid synthesis in Drosophila melanogaster. Insect Biochem. 7, 371-379.
9. Gilliland, G., Perrin, S., Blanchard, K., Bunn, H.F., 1990. Analysis of cytokine mRNA and DNA: detection and quantitation by competitive polymerase chain reaction. Proc. Nat. Acad. Sci. USA 87, 2725-2759.
10. Jallon, J.M., Hotta, Y., 1979. Genetic and behavioral studies of female sex appeal in Drosophila. Behavior Genet. 9, 257-275.
11. Jallon, J.M., Wicker-Thomas, C., 2003. Genetic studies on pheromone production in Drosophila. In: Blomquist, G.J., Vogt, G. (Eds.), Insect Pheromone Biochemistry and Molecular Biology. Part 1. Biochemistry and Molecular Biology of Pheromone Production. Elsevier Academic Press, New York, pp. 253-281.
12. Jallon, J.M., Antony, C., Benamar, O., 1981. Un anti-aphrodisiaque produit par les mâles de Drosophila melanogaster et transfé ré aux femelles lors de la copulation. CR Acad. Sci. Paris 292, 1147-1149.
13. Keith, A.D., 1966. Analysis of lipids in Drosophila melanogaster. Comparative Biochem. Physiol. 17, 1127-1136.
14. Kotake, S., Schumacher Jr., H.R., Wilder, R.L., 1996. A simple nested RT-PCR method for quantitation of the relative amounts of miltiple cytokine mRNAs in small tissue samples. J. Immunol. Methods 199, 193-203.
15. Labeur, C., Dallerac, R., Wicker-Thomas, C., 2002. Involvement of desat1 gene in the control of Drosophila melanogaster pheromone biosynthesis. Genetica 114, 269-274.
16. Miyazaki, M., Dobrzyn, A., Sampath, H., Lee, S.H., Man, W.C., Chu, K., Peters, J.M., Gonzalez, F.J., Ntambi, J.M., 2004. Reduced adiposity and liver steatosis by stearoyl-CoA desaturase Deficiency are independent of peroxisome proliferator-activated receptor-{alpha}. J. Biochem. Chem. 279, 35017-35024.
17. Ntambi, J.M., Miyazaki, M., Stoehr, J.P., Lan, H., Kendziorski, C.M., Yandell, B.S., Song, Y., Cohen, P., Friedman, J.M., Attie, A.D., 2002. Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity. Proc. Nat. Acad. Sci.USA 99, 11482-11486.
18. Pennanec'h, M., Ferveur, J.F., Pho, D.B., Jallon, J.M., 1991. Insect fatty acid related pheromones: a review of their biosynthesis, hormonal regulation and genetic control. Ann. Soc. Entomol. France 27, 245-263.
19. Pennanec'h, M., Bricard, L., Kunesh, G., Jallon, J.M., 1997. Incorporation of fatty acids into cuticular hydrocarbons of male and female Drosophila melanogaster. J. Insect Physiol. 43, 1111-1116.
20. de Renobales, M., Blomquist, G.J., 1984. Biosynthesis of medium chain fatty acids in Drosophila melanogaster. Arch. Biochem. Biophys. 228, 407-414.
21. de Renobales, M., Woodin, T.S., Blomquist, G.J., 1986. Drosophila melanogaster fatty acid synthetase. Characteristics and effect of protease inhibitors. Insect Biochem. 16, 887-894.
22. Santagati, S., Garnier, M., Carlo, P., Violani, E., Picotti, G.B., Maggi, A., 1997. Quantitation of low abundance mRNA in glial cells using different PCR-based methods. Brain Res. Protocols 1, 217-223.
23. Sessler, A.M., Kaur, N., Palta, J.P., Ntambi, J.M., 1996. Regulation of stearoyl-CoA desaturase 1 mRNA stability by polyunsaturated fatty acids in 3T3-L1 adipocytes. J. Biol. Chem. 271, 29854-29858.
24. Sorensen, J.G., Loeschcke, V., 2001. Larval crowding in Drosophila melanogaster induces Hsp70 expression, and leads to increased adult longevity and adult thermal stress resistance. J. Insect Physiol. 47, 1301-1307.
25. Stark, W.S., Lin, T.N., Brackhahn, D., Christianson, J.S., Sun, G.Y., 1993. Fatty acids in the lipids of Drosophila heads: effects of visual mutants, carotenoid deprivation and dietary fatty acids. Lipids 28, 345-350.
26. Toba, G., Ohsako, T., Miyata, N., Ohtsuka, T., Seong, K.H., Aigaki, T., 1999. The gene search system. A method for efficient detection and rapid molecular identification of genes in Drosophila melanogaster. Genetics 151, 725-737.
27. Venard, D., Jallon, J.M., 1980. Evidence for an aphrodisiac pheromone of female Drosophila. Experientia 36, 211-212.
28. Wicker, C., Jallon, J.M., 1995. Hormonal control of sex pheromone biosynthesis in Drosophila melanogaster. J. Insect Physiol. 41, 65-70.
29. Wicker-Thomas, C., Henriet, C., Dallerac, R., 1997. Partial characterization of a fatty acid desaturase gene in Drosophila melanogaster. Insect Biochem. Mol. Biol. 27, 963-972.
30. Wodarz, A., Hinz, U., Engelbert, M., Knust, E., 1995. Expression of crumbs confers apical character on plasma membrane domains of ectodermal epithelia of Drosophila. Cell 82, 67-76.
31. Yin, H., Norris, D.E., Lanzaro, G.C., 2000. Sibling species in the Lutzomyia longipalpis complex differ in levels of mRNA expression for the salivary peptide, maxadilan. Insect Mol. Biol. 9, 309-314.
32. Zhou, G., Myers, R., Li, Y., Chen, Y., Shen, X., Fenyk-Melody, J., Wu, M., Ventre, J., Doebber, T., Fujii, N., Musi, N., Hirshman, M.F., Goodyear, L..J., Moller, D.E., 2001. Role of AMP-activated protein kinase in mechanism of metformin action. Clin. Invest. 108, 1167-1174.