Identification of a novel nucleus protein involved in the regulation of urokinase in 95D cells

Acta Biochimica et Biophysica Sinica

Volumn 37, Issue 5, 2005, Pages 303-309

  Tong, Chang ^a   Tan, Li ^a   Li, Ping ^a   Zhu, Yun Song ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

PBK1; Urokinase type plasminogen activator (uPA)

Indexed keywords

NUCLEAR PROTEIN; PLACENTA PROTEIN; RIBOSOME PROTEIN; RSL1D1 PROTEIN, HUMAN; UROKINASE;

ARTICLE; CELL FRACTIONATION; CELL NUCLEUS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; LUNG TUMOR; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

CELL LINE, TUMOR; CELL NUCLEUS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; LUNG NEOPLASMS; NUCLEAR PROTEINS; PREGNANCY PROTEINS; RIBOSOMAL PROTEINS; SUBCELLULAR FRACTIONS; URINARY PLASMINOGEN ACTIVATOR;

EID: 23844522644     PISSN: 16729145     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1745-7270.2005.00041.x     Document Type: Article

References (21)

1. Aplin JD. Implantation, trophoblast differentiation and haemochorial placentation: Mechanistic evidence in vivo and in vitro. J Cell Sci 1991, 99: 681-692
2. Liotta LA, Steeg PS, Stetler-Stevenson WG. Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation. Cell 1991, 64, 327-336
3. Teesalu T, Blasi F, Talarico D. Expression and function of the urokinase-type plasminogen activator during mouse hemochorial placental development. Dev Dyn 1998, 213: 27-38
4. Andreasen PA, Kjøller L, Christensen L, Duffy MJ. The urokinase-type plasminogen activator system in cancer metastasis: A review. Int J Cancer 1997, 72: 1-22
5. Tecimer C, Doering DL, Goldsmith LJ, Meyer JS, Abdulhay G, Wittliff JL. Clinical relevance of urokinase-type plasminogen activator, its receptor, and its inhibitor type 1 in endometrial cancer. Gynecol Oncol 2001, 80: 48-55
6. Duffy MJ, Maguire TM, McDermott EW, O'Higgins N. Urokinase plasminogen activator: A prognostic marker in multiple types of cancer. J Surg Oncol 1999, 71: 130-135
7. Cassady AI, Stacey KJ, Nimmo KA, Murphy KM, von der Ahe D, Pearson D, Botteri FM et al. Constitutive expression of the urokinase plasminogen activator gene in murine RAW264 macrophages involves distal and 5′ non-coding sequences that are conserved between mouse and pig. Nucleic Acids Res 1991, 19: 6839-6847
8. Nerlov C, Rorth P, Blasi F, Johnsen M. Essential AP-1 and PEA3 binding elements in the human urokinase enhancer display cell type-specific activity. Oncogene 1991, 6: 1583-1592
9. Gutman A, Wasylyk B. The collagenase gene promoter contains a TPA and oncogene-responsive unit encompassing the PEA3 and AP-1 binding sites. EMBO J 1990, 9: 2241-2246
10. Lee JS, von der Ahe D, Kiefer B, Nagamine Y. Cytoskeletal reorganization and TPA differently modify AP-1 to induce the urokinase-type plasminogen activator gene in LLC-PK1 cells. Nucleic Acids Res 1993, 21: 3365-3372
11. Nerlov C, de Cesare D, Pergola F, Caracciolo A, Blasi F, Johnsen M, Verde P. A regulatory element that mediates co-operation between a PEA3-AP-1 element and an AP-1 site is required for phorbol ester induction of urokinase enhancer activity in HepG2 hepatoma cells. EMBO J 1992, 11: 4573-4582
12. Berthelsen J, Vandekerkhove J, Blasi F. Purification and characterization of UEF3, a novel factor involved in the regulation of the urokinase and other AP-1 controlled promoters. J Biol Chem 1996, 271: 3822-3830
13. de Cesare D, Palazzolo M, Berthelsen J, Blasi F. Characterization of UEF-4, a DNA-binding protein required for transcriptional synergism between two AP-1 sites in the human urokinase enhancer. J Biol Chem 1997, 272: 23921-23929
14. Huch G, Hohn HP, Denker HW. Identification of differentially expressed genes in human trophoblast cells by differential-display RT-PCR. Placenta 1998, 19: 557-567
15. Zini JM, Murray SC, Graham CH, Lala PK, Kariko K, Barnathan ES, Mazar A et al. Characterization of urokinase receptor expression by human placental trophoblasts. Blood 1992, 79: 2917-2729
16. Aguirre Ghiso JA, Alonso DF, Farías EF, Gomez DE, de Kier Joffè EB. Deregulation of the signaling pathway controlling urokinase production: Its relationship with the invasive phenotype. Eur J Biochem 1999, 263: 295-304
17. D'Orazio D, Besser D, Marksitzer R, Kunz C, Hume DA, Kiefer B, Nagumine Y. Cooperation of two PEA3/AP1 sites in uPA gene induction by TPA and FGF-2. Gene 1997, 201: 179-187
18. Verde P, Boast S, Franze A, Robbiati F, Blasi F. An upstream enhancer and a negative element in the 5′ flanking region of the human urokinase plasminogen activator gene. Nucleic Acids Res 1988, 16: 10699-10716
19. de Cesare D, Palazzolo M, Blasi F. Functional characterization of COM, a DNA region required for cooperation between AP-1 sites in urokinase gene transcription. Oncogene 1996, 13: 2551-2562
20. Palazzolo M, Berthelsen J, de Cesare D, Blasi F. Oct-1 specifically binds the UEF4 site of the human AP1-regulated urokinase enhancer. Eur J Biochem 2000, 267: 5427-5437
21. Berthelsen J, Zappavigna V, Mavilio F, Blasi F. Prep1, a novel functional partner of Pbx proteins. EMBO J 1998, 17: 1423-1433