Studies on synthesis of quaternary ammonium salt derivatives of haloperidol and their vasodilative activities

Chinese Pharmaceutical Journal

Volumn 40, Issue 12, 2005, Pages 947-951

  Zheng, Jin Hong ^a   Wang, Jin Zhi ^a   Shi, Gang Gang ^a  

^a SHANTOU UNIVERSITY   (China)

Author keywords

Haloperidol; Quaternary ammonium salt; Structure activity relationship; Synthesis; Vasodilative activities

Indexed keywords

AROMATIC COMPOUNDS; DERIVATIVES; DRUG PRODUCTS; INFRARED SPECTROSCOPY; LEAD COMPOUNDS; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE (COMPOSITION);

HALOPERIDOL; QUATERNARY AMMONIUM SALTS; STRUCTURE ACTIVITY RELATIONSHIPS; VASODILATIVE ACTIVITIES;

AMMONIUM COMPOUNDS;

BENZYL CHLORIDE; BENZYL HALOPERIDOL CHLORIDE DERIVATIVE; CARBONYL DERIVATIVE; COMPOUND F11; DRUG DERIVATIVE; F 11; HALOPERIDOL; HALOPERIDOL DERIVATIVE; HYDROHALOPERIDOL; HYDROXYL GROUP; QUATERNARY AMMONIUM DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; AORTA; ARTICLE; CHEMICAL ANALYSIS; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTRICAL PARAMETERS; ELEMENTAL ANALYSIS; IN VITRO STUDY; INFRARED SPECTROSCOPY; ISOLATED ARTERY; MASS SPECTROMETRY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RABBIT; RAT; REDUCTION; STRUCTURE ACTIVITY RELATION; VASODILATATION;

EID: 23844498706     PISSN: 10012494     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Shi GG, Fang H, Zheng JH. Quaternary ammonium salt derivative of haloperidol inhibits KCl-induced calcium increase in rat aortic smooth muscle cell[J]. Acta Pharmacol Sin, 2001,22(9):837.