Is cardiac troponin T serum level an accurate surrogate for acute doxorubicin-related myocardial injury? [5]

Annals of Oncology

Volumn 16, Issue 8, 2005, Pages 1403-1404

  Ferretti, Gia ^a   Mandala M ^b   Bria, E ^a   Papaldo, P ^a   Carlini, P ^a   Fabi, A ^a   Milella, M ^a   Ruggeri, E M ^a   Nistico C ^a   Cognetti, F ^a  

^a REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^b TREVIGLIO HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 PROPANEDIAMINE N,N' DIACETAMIDE N,N' DIACETIC ACID; DOXORUBICIN; RAZOXANE; TROPONIN T;

CANCER; CARDIOMYOPATHY; CARDIOTOXICITY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DISEASE MARKER; DRUG MECHANISM; EARLY DIAGNOSIS; HEART FUNCTION; HEART MUSCLE INJURY; HISTOPATHOLOGY; HUMAN; LETTER; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PREDICTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN SECRETION;

ANTIBIOTICS, ANTINEOPLASTIC; BIOLOGICAL MARKERS; DOXORUBICIN; HEART; HUMANS; MYOCARDIAL INFARCTION; PROGNOSIS; TROPONIN T;

EID: 23844485577     PISSN: 09237534     EISSN: None     Source Type: Journal    
DOI: 10.1093/annonc/mdi203     Document Type: Letter

References (5)

1. Lipshultz SE, Rifai N, Dalton VM et al. The effect of dexrazoxane on myocardial injury in doxorubicin-treated children with acute lymphoblastic leukemia. N Engl J Med 2004; 351: 145-153.
2. Herman EH, Zhang J, Lipshultz SE et al. Correlation between serum levels of cardiac troponin-T and the severity of the chronic cardiomyopathy induced by doxorubicin. J Clin Oncol 1999; 17: 2237-2243.
3. Herman EH, Zhang J, Rifai N et al. The use of serum levels of cardiac troponin T to compare the protective activity of dexrazoxane against doxorubicin- and mitoxantrone-induced cardiotoxicity. Cancer Chemother Pharmacol 2001; 48: 297-304.
4. Lim CC, Zuppinger C, Guo X, Kuster GM, Helmes M, Eppenberger HM, Suter TM, Liao R, Sawyer DB. Anthracyclines induce calpaindependent titin proteolysis and necrosis in cardiomyocytes. J Biol Chem 2004; 279: 8290-8299.
5. Minotti G, Menna P, Salvatorelli E et al. Anthracyclines: Molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev 2004; 56: 185-229.