Zebrafish penner/lethal giant larvae 2 functions in hemidesmosome formation, maintenance of cellular morphology and growth regulation in the developing basal epidermis

Development

Volumn 132, Issue 14, 2005, Pages 3255-3265

  Sonawane, Mahendra ^a   Carpio, Yamila ^a,b   Geisler, Robert ^a   Schwarz, Heinz ^a   Maischein, Hans Martin ^a   Nuesslain Volhard, Christiane ^a  

^a MAX PLANCK INSTITUTE FOR DEVELOPMENTAL BIOLOGY   (Germany)

^b CENTER FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Cuba)

Author keywords

Cell proliferation; Epidermis; Hemidesmosomes; penner lgl2; Zebrafish

Indexed keywords

DROSOPHILA PROTEIN; LETHAL GIANT LARVAE 2 PROTEIN; PROTEIN LGL2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BASAL CELL; CELL MATURATION; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; GROWTH REGULATION; HEMIDESMOSOME; LARVAL DEVELOPMENT; MOLECULAR GENETICS; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; ORGANOGENESIS; ORTHOLOGY; PRIORITY JOURNAL; PROTEIN FUNCTION; TISSUE STRUCTURE; TUMOR SUPPRESSOR GENE; VERTEBRATE; ZEBRA FISH;

AMINO ACID SEQUENCE; ANIMALS; DROSOPHILA PROTEINS; EPIDERMIS; GENES, LETHAL; HEMIDESMOSOMES; MICROSCOPY, INTERFERENCE; MOLECULAR SEQUENCE DATA; TUMOR SUPPRESSOR PROTEINS; ZEBRAFISH; ZEBRAFISH PROTEINS;

ANIMALIA; DANIO RERIO; VERTEBRATA;

EID: 23844484860     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.01904     Document Type: Article

References (36)

1. Bergstraesser, L. M., Srinivasan, G., Jones, J. C., Stahl, S. and Weitzman, S. A. (1995). Expression of hemidesmosomes and component proteins is lost by invasive breast cancer cells. Am. J. Pathol. 147, 1823-1839.
2. Betschinger, J., Mechtler, K. and Knoblich, J. A. (2003). The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl. Nature 422, 326-330.
3. Bilder, D. (2004). Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors. Genes Dev. 18, 1909-1925.
4. Bilder, D. and Perrimon, N. (2000). Localisation of apical epithelial determinants by the basolateral PDZ protein Scribble. Nature 403, 676-680.
5. Bilder, D., Li, M. and Perrimon, N. (2000). Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors. Science 289, 113-116.
6. Bilder, D., Schober, M. and Perrimon, N. (2003). Integrated activity of PDZ protein complexes regulates epithelial polarity. Nat. Cell Biol. 5, 53-58.
7. Borradori, L. and Sonnenberg, A. (1996). Hemidesmosomes: roles in adhesion, signaling and human diseases. Curr. Opin. Cell Biol. 8, 647-656.
8. Chalmers, A. D., Pambos, M., Mason, J., Lang, S., Wylie, C. and Papalopulu, N. (2005). aPKC, Crumbs3 and Lgl2 control apicobasal polarity in early vertebrate development. Development 132, 977-986.
9. Fuchs, E. and Raghavan, S. (2002). Getting under the skin of epidermal morphogenesis. Nat. Rev. Genet. 3, 199-209.
10. Gateff, E. (1978). Malignant neoplasms of genetic origin in Drosophila melanogaster. Science 200, 1448-1459.
11. Geisler, R. (2002). Zebrafish: A practical approach. Oxford: Oxford University Press.
12. Grifoni, D., Garoia, F., Schimanski, C. C., Schmitz, G., Laurenti, E., Galle, P. R., Pession, A., Cavicchi, S. and Strand, D. (2004). The human protein Hugl-1 substitutes for Drosophila Lethal giant larvae tumour suppressor function in vivo. Oncogene 23, 8688-8694.
13. Herold-Mende, C., Kartenbeck, J., Tomakidi, P. and Bosch, F. X. (2001). Metastatic growth of squamous cell carcinomas is correlated with upregulation and redistribution of hemidesmosomal components. Cell Tissue Res. 306, 399-408.
14. Humbert, P., Russell, S. and Richardson, H. (2003). Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer. BioEssays 25, 542-553.
15. Kagami, M., Toh-e, A. and Matsui, Y. (1998). Sro7p, a Saccharomyces cerevisiae counterpart of the tumor suppressor l(2)gl protein, is related to myosins in function. Genetics 149, 1717-1727.
16. Kiernan, J. A. (2001). Histological and Histochemical Methods: Theory and Practice. London: Arnold.
17. Klezovitch, O., Fernandez, T. E., Tapscott, S. J. and Vasioukhin, V. (2004). Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice. Genes Dev. 18, 559-571.
18. Manfruelli, P., Arquier, N., Hanratty, W. P. and Semeriva, M. (1996). The tumor suppressor gene, lethal(2)giant larvae (l(2)gl), is required for cell shape change of epithelial cells during Drosophila development. Development 122, 2283-2294.
19. Mariotti, A., Kedeshian, P. A., Dans, M., Curatola, A. M., Gagnoux-Palacios, L. and Giancotti, F. G. (2001). EGF-R signaling through Fyn kinase disrupts the function of integrin alpha6beta4 at hemidesmosomes: role in epithelial cell migration and carcinoma invasion. J. Cell Biol. 155, 447-458.
20. Musch, A., Cohen, D., Yeaman, C., Nelson, W. J., Rodriguez-Boulan, E. and Brennwald, P. J. (2002). Mammalian homolog of Drosophila tumor suppressor lethal (2) giant larvae interacts with basolateral exocytic machinery in Madin-Darby canine kidney cells. Mol. Biol. Cell 13, 158-168.
21. Ohshiro, T., Yagami, T., Zhang, C. and Matsuzaki, F. (2000). Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast. Nature 408, 593-596.
22. Pagliarini, R. A. and Xu, T. (2003). A genetic screen in Drosophila for metastatic behaviour. Science 302, 1227-1231.
23. Peng, C. Y., Manning, L., Albertson, R. and Doe, C. Q. (2000). The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila reuroblasts. Nature 408, 596-600.
24. Plant, P. J., Fawcett, J. P., Lin, D. C., Holdorf, A. D., Binns, K., Kulkarni, S. and Pawson, T. (2003). A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl. Nat. Cell Biol. 5, 301-308.
25. Pulkkinen, L. and Uitto, J. (1999). Mutation analysis and molecular genetics of epidermolysis bullosa. Matrix Biol. 18, 29-42.
26. Rabinovitz, I., Toker, A. and Mercurio, A. M. (1999). Protein kinase C-dependent mobilization of the alpha6beta4 integrin from hemidesmosomes and its association with actin-rich cell protrusions drive the chemotactic migration of carcinoma cells. J. Cell Biol. 146, 1147-1160.
27. Schenk, P. (1979). The fate of hemidesmosomes in laryngeal carcinoma. Arch. Otorhinolaryngol. 222, 187-198.
28. Schulte-Merker, S. (2002). Zebrafish: A Practical Approach. Oxford, UK: Oxford University Press.
29. Shimoda, N., Knapik, E. W., Ziniti, J., Sim, C., Yamada, E., Kaplan, S., Jackson, D., de Sauvage, F., Jacob, H. and Fishman, M. C. (1999). Zebrafish genetic map with 2000 microsatellite markers. Genomics 58, 219-232.
30. Strand, D., Raska, I. and Mechler, B. M. (1994). The Drosophila lethal(2)giant larvae tumor suppressor protein is a component of the cytoskeleton. J. Cell Biol. 127, 1345-1360.
31. Strand, D., Unger, S., Corvi, R., Hartenstein, K., Schenkel, H., Kalmes, A., Merdes, G., Neumann, B., Krieg-Schneider, F., Coy, J. F. et al. (1995). A human homologue of the Drosophila tumour suppressor gene l(2)gl maps to 17p11.2-12 and codes for a cytoskeletal protein that associates with nonmuscle myosin II heavy chain. Oncogene 11, 291-301.
32. Tanentzapf, G. and Tepass, U. (2003). Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization. Nat. Cell Biol. 5, 46-52.
33. van Eeden, F. J., Granato, M., Schach, U., Brand, M., Furutani-Seiki, M., Haffter, P., Hammerschmidt, M., Heisenberg, C. P., Jiang, Y. J., Kane, D. A. et al. (1996). Genetic analysis of fin formation in the zebrafish, Danio rerio. Development 123, 255-262.
34. Woods, D. F., Hough, C., Peel, D., Callaini, G. and Bryant, P. J. (1996). Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia. J. Cell Biol. 134, 1469-1482.
35. Woods, D. F., Wu, J. W. and Bryant, P. J. (1997). Localization of proteins to the apico-lateral junctions of Drosophila epithelia. Dev. Genet. 20, 111-118.
36. Yamanaka, T., Horikoshi, Y., Sugiyama, Y., Ishiyama, C., Suzuki, A., Hirose, T., Iwamatsu, A., Shinohara, A. and Ohno, S. (2003). Mammalian Lgl forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity. Curr. Biol. 13, 734-743.