Differential expression of the LGI and SLIT families of genes in human cancer cells

Gene

Volumn 356, Issue 1-2, 2005, Pages 85-90

  Rossi, Michael R ^a   Huntoon, Kristin ^a   Cowell, John K ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

Glioma; Neuroblastoma; Tumor; Tumorigenesis

Indexed keywords

ARTICLE; CANCER CELL; CARCINOGENESIS; CELL LINE; CELL TYPE; CONTROLLED STUDY; GENE; GENE EXPRESSION; GENE FUNCTION; GENE INACTIVATION; HUMAN; HUMAN CELL; LEUCINE RICH GLIOMA INACTIVATED 1; PRIORITY JOURNAL; SLIT GENE;

BREAST NEOPLASMS; CELL LINE, TUMOR; CPG ISLANDS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HUMANS; MELANOMA; NEOPLASMS; NERVE TISSUE PROTEINS; NEUROBLASTOMA; PROMOTER REGIONS (GENETICS); PROTEIN ISOFORMS; PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, NEOPLASM;

EID: 23844472049     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2005.04.018     Document Type: Article

References (24)

1. A. Bagri Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain Neuron 33 2002 233 248
2. R. Battye, A. Stevens, R.L. Perry, and J.R. Jacobs Repellent signaling by Slit requires the leucine-rich repeats J. Neurosci. 21 2001 4290 4298
3. R. Besleaga, M. Montesinos-Rongen, J. Perez-Tur, R. Siebert, and M. Deckert Expression of the LGI1 gene product in astrocytic gliomas: downregulation with malignant progression Virchows Arch. 443 2003 561 564
4. O.B. Chernova, R.P. Somerville, and J.K. Cowell A novel gene, LGI1, from 10q24 is rearranged and downregulated in malignant brain tumors Oncogene 17 1998 2873 2881
5. J.K. Cowell, and T.R. Rupniak Chromosome analysis of human neuroblastoma cell line TR 14 showing double minutes and an abnormality involving chromosome 1 Cancer Genet. Cytogenet. 9 1983 273 280
6. J.K. Cowell Application of bacterial artificial chromosome array-based comparative genomic hybridization and spectral karyotyping to the analysis of glioblastoma multiforme Cancer Genet. Cytogenet. 151 1 2004 36 51
7. A. Dallol SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers Cancer Res. 62 2002 5874 5880
8. A. Dallol, D. Krez, L. Hesson, C. Eng, E.R. Maher, and F. Latif Frequent epigenetic inactivation of the SLIT2 gene in gliomas Oncogene 17 2003 4611 4616
9. A. Dallol, D. Morton, E.R. Maher, and F. Latif SLIT2 axon guidance molecule is frequently inactivated in colorectal cancer and suppresses growth of colorectal carcinoma cells Cancer Res. 63 2003 1054 1058
10. W. Gu, E. Brodtkorb, and O.K. Steinlein LGI1 is mutated in familial temporal lobe epilepsy characterized by aphasic seizures Ann. Neurol. 52 2002 364 367
11. W. Gu The LGI1 gene involved in lateral temporal lobe epilepsy belongs to a new subfamily of leucine-rich repeat proteins FEBS Lett. 519 2002 71 76
12. S. Kalachikov Mutations in LGI1 cause autosomal-dominant partial epilepsy with auditory features Nat. Genet. 30 2002 335 341
13. P. Kleihues W.K. Cavenee Pathology and Genetics of Tumors of the Nervous System 2000 IARC Press Lyon, France
14. D. Krex, B. Mohr, M. Hauses, G. Ehninger, H.K. Schackert, and G. Schackert Identification of uncommon chromosomal aberrations in the neuroglioma cell line H4 by spectral karyotyping P. Kunapuli K.S. Chitta J.K. Cowell Suppression of the Cell Proliferation and Invasion Phenotypes in Glioma Cells by the LGI1 Gene J. Neuro-oncol. 52 2001 119 128
15. P. Kunapuli, K. Chitta, and J.K. Cowell Suppression of the cell proliferation and invasion phenotypes in glioma cells by the LGI1 gene Oncogene 22 2003 3985 3991
16. P. Kunapuli, C. Kasyapa, L. Hawthorn, and J.K. Cowell LGI1, a putative tumor metastasis suppressor gene, controls in vitro invasiveness and expression of matrix metalloproteinases in glioma cells through the Erk1/2 pathway J. Biol. Chem. 279 2004 23151 23157
17. A. Latil Quantification of expression of netrins, slits and their receptors in human prostate tumors Int. J. Cancer 103 2003 306 315
18. A.K. McAllister Conserved cues for axon and dendrite growth in the developing cortex Neuron 33 2002 2 4
19. R. Ottman Localization of a gene for partial epilepsy to chromosome 10q Nat. Genet. 10 1995 56 60
20. A.S. Plumb Slit1 and Slit2 cooperate to prevent premature midline crossing of retinal axons in the mouse visual system Neuron 33 2002 219 232
21. H.D. Soule Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10 Cancer Res. 50 1990 6075 6086
22. E. Staub The novel EPTP repeat defines a superfamily of proteins implicated in epileptic disorders Trends Biochem. Sci. 27 2002 441 444
23. K.J. Sweadner, and E. Rael The FXYD gene family of small ion transport regulators or channels: cDNA sequence, protein signature sequence, and expression Genomics 68 2000 41 56
24. A. Szklarczyk, J. Lapinska, M. Rylski, R.D. McKay, and L. Kaczmarek Matrix metalloproteinase-9 undergoes expression and activation during dendritic remodeling in adult hippocampus J. Neurosci. 22 2002 920 930