Serum adenosine deaminase and procalcitonin concentrations in neutropenic febrile children with acute lymphoblastic leukaemia

Clinical and Experimental Medicine

Volumn 5, Issue 2, 2005, Pages 60-65

  Hitoglou Hatzi, S ^a   Hatzistilianou, M ^a   Gougoustamou, D ^a   Rekliti, A ^a   Agguridaki, Ch ^a   Athanassiadou, F ^a   Frydas, S ^a   Kotsis, A ^a   Catriu, D ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

ALL; Isoenzymes of ada; Neutropenia; PCT; tADA

Indexed keywords

ADENOSINE DEAMINASE; ADENOSINE DEAMINASE 1; ADENOSINE DEAMINASE 2; C REACTIVE PROTEIN; ISOENZYME; MARKER; PROCALCITONIN; UNCLASSIFIED DRUG;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ANTIMICROBIAL THERAPY; ARTICLE; BLOOD CULTURE; BLOOD SAMPLING; CANCER CHEMOTHERAPY; CHILD; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; FEBRILE NEUTROPENIA; FEMALE; FEVER; HEMOCONCENTRATION; HOSPITAL ADMISSION; HUMAN; INFECTION; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN ANALYSIS; SEROLOGY;

ADENOSINE DEAMINASE; ADOLESCENT; CALCITONIN; CHILD; CHILD, PRESCHOOL; FEMALE; FEVER; HUMANS; INFANT; LEUKEMIA, LYMPHOCYTIC, ACUTE, L1; MALE; NEUTROPENIA; PROTEIN PRECURSORS;

EID: 23844455201     PISSN: 15918890     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10238-005-0067-2     Document Type: Article

References (31)

1. Finberg RW, Talcott JA (1999) Fever and neutropenia - how to use a new treatment strategy. N Engl J Med 341:362-363
2. Hughes WT, Armstrong D, Bodey GP, Brown AE, Edwards JE, Feld R, Pizzo PA, Rolston KVI, Shenep JL, Young LS (1997) Guidelines for the use of antimicrobial agents in neutropenic patients with unexplained fever. Clin Infect Dis 25:551-573
3. Hubel K, Hegener K, Schnell R, Mansmann G, Oberhauser F, Staib P, Diehl V, Engert A (1999) Suppressed neutrophil function as a risk factor for severe infection after cytotoxic chemotherapy in patients with acute nonlymphocytic leukemia. Hematology 78:73-77
4. Schimpff SC (1995) Infections in the cancer patients - diagnosis, prevention and treatment. In: Mandell GL, Douglas RG, Bennet JE (eds) Principles and practice of infectious diseases. Churchill Livingstone, New York, pp 2666-2275
5. Christ-Crain M, Jaccard-Stolz D, Bingisser R, Gencay M, Huber P, Tamm M, Muller B (2004) Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: cluster-randomised, single-blinded intervention trial. Lancet 363:600-607
6. The Immunocompromised Host Society (1990) The design, analysis, and reporting of clinical trials on the empirical antibiotic management of the neutropenic patient. J Infect Dis 161:397-401
7. Lehrnbecher T, Venzon D, de Haas M, Chanock SJ, Kuel J (1999) Assessment of measuring circulating levels of interleukin-6, interleukin-8, C-reactive protein, soluble Fc gamma receptor type III, and mannose-binding protein in febrile children with cancer and neutropenia. Clin Infect Dis 29:414-419
8. Manian FA (1995) A prospective study of daily measurement of C-reactive protein in serum of adults with neutropenia. Clin Infect Dis 21:114-121
9. Hansson LO, Lindquist L (1997) C-reactive protein: its role in the diagnosis and follow-up of infectious diseases. Curr Opin Infect Dis 10:196-201
10. Gendel D, Bohuon C (1997) Procalcitonin a marker of bacterial infection. Infection 25:133-134
11. Ruokonen E, Nousiainen T, Pulkki K, Takala J (1999) Procalcitonin concentrations in patients with neutropenic fever. Eur J Clin Microbiol Infect Dis 18:283-285
12. Hatzistilianou M, Hitoglou S, Gougoustamou D, Rekliti A, Tzouvelekis G, Nanas C, Catriu D, Kotsis A (2002) Serum procalcitonin, adenosine deaminase and its isoenzymes in the aetiological diagnosis of pneumonia in children. Int J Immunopathol Pharmacol 15:119-127
13. Whang KT, Steinwald PM, White JC (1998) Serum calcitonin precursors in sepsis and systemic inflammation. J Clin Endocrinol Metab 83:3296-3301
14. Bernard L, Ferriere F, Casassus P, Malas E, Leveque S, Guillevin L (1998) Procalcitonin as an early marker of bacterial infection in severely neutropenic febrile adults. Clin Infect Dis 27:914-915
15. Conway EJ, Cooke R (1929) The deaminase of adenosine and adenylic acid in blood and tissues. Biochem J 33:479-492
16. Adams A, Harkness RA (1976) Adenosine deaminase activity in thymus and other human tissues. Clin Exp Immunol 26:649-649
17. Hitoglou S, Hatzistilianou M, Gougoustamou D, Athanassiadou F, Kotsis A, Catriu D (1998) Adenosine deaminase activity and isozyme levels in serum and peripheral blood lymphocytes in childhood acute lymphoblastic leukemia. Molecul Immunol 35:754
18. Hirschorn R, Ratech H (1980) Isozymes of adenosine deaminase. In: Ratazzi MC, Scandalia JG, White GS (eds) Current topics in biological and medical research, Vol 1. Alan R. Liss, New York, pp 132-157
19. Conlon BA, Law WR (2004) Macrophages are a source of extracellular adenosine deaminase-2 during inflammatory responses. Clin Exp Immunol 138:14-20
20. Gakis C (1996) Adenosine deaminase (ADA) isoenzymes ADA1 and ADA2: diagnostic and biological role. Eur Respir J 9:632-633
21. Giusti G (1974) Adenosine deaminase. In: Bergmayer HU (ed) Methods of enzymatic analysis, Vol 2, 2nd edn, Academic Press, New York, pp 1092-1099
22. Muraoka T, Katsuramaki T, Shiraishi H, Yokoyama MM (1990) Automated enzymatic measurement of adenosine deaminase isoenzyme activities in serum. Anal Biochem 187:268-272
23. Crokaert F (2000) Febrile neutropenia in children. Int J Antimicrob Agents 16:173-176
24. Alexander SW, Pizzo PA (1999) Current considerations in the management of fever and neutropenia. In: Remington JS, Swartz MN (eds) Current clinical topics in infectious diseases. Blackwell Science, pp 160-180
25. Von Lilienfeld-Toal M, Dietrich MP, Glasmacher A, Lehmann L, Breig P, Hahn C, Schmidt-Wolf IGH, Marklein G, Schroeder S, Stuber F (2004) Markers of bacteremia in febrile neutropenic patients with hematological malignancies: procalcitonin and IL-6 are more reliable than C-reactive protein. Eur J Clin Macrobiol Infect Dis 23:539-544
26. Person L, Engervall P, Magnuson A, Vikerfors T, Soderquist B, Hansson L, Tidefelt U (2004) Use of inflammatory markers for early detection of bacteraemia in patients with febrile neutropenia. Scand J Infect Dis 36:365-371
27. Ciaccio M, Fugardi G, Titone L, Romano A, Giordano S, Bivona G, Scarlata F, Vocca L, Di Gangi M (2004) Procalcitonin levels in plasma in oncohaematologic patients with and without bacterial infections. Clin Chim Acta 340:149-152
28. Penel N, Foyrnier C, Clisant S, N'Guyen M (2004) Causes of fever and value of C-reactive protein and procalcitonin in differentiating infections from paraneoplastic fever. Support Care Cancer 12:593-598
29. Hatzistilianou M, Athanassiadou F, Catriu D, Makedou A, Hitoglou S, Papaeconomou A (1996) Prognostic significance of adenosine deaminase in children with malignancies. Pediatr Hemat Oncol 13:339-347
30. Gourine AV, Dale N, Gourine VN, Spyer KM (2004) Fever in systemic inflammation: roles of purines. Front Biosci 9:1011-1022
31. Cronstein BD (1997) The mechanism of action of methotrexate. Rheum Dis Clin North Am 23:735-755