Influence of elemene on the expression of Bcl-2 family genes in rat C6 glioma cells

National Medical Journal of China

Volumn 85, Issue 24, 2005, Pages 1700-1703

  Xu, Ying Hui ^a   Dong, Bin ^a   Luo, Qi Zhong ^a   Zhuo, Hong Yu ^a   Jia, Yi Chang ^a   Yang, You Feng ^a   Wang, Yi Zheng ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Caryophyllene oxide; Genes, bcl 2; Glioma

Indexed keywords

BETA ELEMENE; ELEMENE; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL X; PROTEIN BCL XL; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL COUNT; CELL CULTURE; CONTROLLED STUDY; GENE EXPRESSION; GLIOMA CELL; NONHUMAN; PROTEIN FAMILY; PROTO ONCOGENE; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-X PROTEIN; CELL LINE, TUMOR; GENES, BCL-2; GLIOMA; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RNA, MESSENGER; SESQUITERPENES;

EID: 23844448005     PISSN: 03762491     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. LI CG, LI ML, SHU XH, et al. Effect of elemene on the phospholipid tranformation rate and membrane fluidity of human BIU-87 cells, Nat Med J China, 2004, 84:416-417.
2. Zuo YF. Experimental study on apoptosis in Hca-F25/Cl-16A3 cells induced by elemene, Pharm Clin Chin Materia Medic, 1998,14:20-22.
3. Noriaki Sakuragi, Alaa-eldin Salah-eldin, Hidemichi Watari, et al. Bax, Bcl-2, and p53 expression in endometrial cancer. Gynec Oncol, 2002,86:288-296.
4. Papa F, Scaccob S, Vergari R, et al. Expression and subcellular distribution of Bcl-2 and Bax proteins in serum-starved human keratinocytes and mouth carcinoma epidermoid cultures. Life Sciences, 2003,73:2865-2872.
5. Zhou YH, Tan F, Hess KR. et al. The expression of PAX6, PTEN, vascular endothelial growth factor, and epidermal growth factor receptor in gliomas: relationship to tumor grade and survival. Clin Cancer Res,2003,9:3369-3375.
6. Su JD, Mayo LD, Donner DB, et al. PTEN and phosphatidylinositol 3′-kinase inhibitors up-regulate p53 and block tumor-induced angiogenesis: evidence for an effect on the tumor and endothelial compartment. Cancer Res, 2003,63:3585-3592.
7. Hou Q, Cymbalyuk E, Hsu SC, et al. Apoptosis modulatory activities of transiently expressed Bcl-2: roles in cytochrome C release and Bax regulation. Apoptosis,2003,8: 617-629.
8. Prayson RA. Cyclooxygenase-2, Bcl-2, and chromosome 1p analysis in protoplasmic astrocytomas. Hum Pathol,2004,35: 317-321.
9. Oltvai ZN, Milliman CL, Korsmeyer SJ. Bcl-2 heterodimerizes in vivo with a conserved homologenous Bax, that accelerates programmed cell death. Cell,1993,74: 609-619.
10. Zhu CJ, Li YB, Wong MC. Expression of antisense Bcl-2 cDNA abolishes tumorigenicity and enhances chemosensitivity of human malignant glioma cells. J Neurosci Res,2003,74:60-66.
11. Suresh TN, Santosh V, Yasha TC, et al. Medulloblastoma with extensive nodularity: a variant occurring in the very young-clinicopathological and immunohistochemical study of four cases. Childs Nerv Syst,2004,20:55-60.
12. Jiang Z, Zheng X, Rich KM. Down-regulation of Bcl-2 and Bcl-xL expression with bispecific antisense treatment in glioblastoma cell lines induce cell death. Neurochem, 2003,84:273-281.
13. Chen GG, Chak EC, Chun YS, et al. Glioma apoptosis induced by macrophages involves both death receptor-dependent and independent pathways. J Lab Clin Med, 2003,141: 190-199.