Cardiovascular phenotypes and functional parameters in the general population - Results of the MONICA/KORA studies

Gesundheitswesen

Volumn 67, Issue SUPPL. 1, 2005, Pages

  Schunkert, H ^a   Doring A ^b   Kuch, B ^c   Holmer, S ^d   Luchner, A ^d   Muscholl, M ^d   Fischer, M ^d   Hengstenberg, C ^d   Riegger, G A J ^d   Hense, H W ^e  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c KLINIKUM AUGSBURG   (Germany)

^d UNIVERSITY HOSPITAL REGENSBURG   (Germany)

^e UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Genetics; Heart failure; Left ventricular hypertrophy; Obesity

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; NATRIURETIC FACTOR; BRAIN NATRIURETIC PEPTIDE; NEUROHORMONE;

BLOOD PRESSURE; BODY COMPOSITION; BODY FAT; BODY MASS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR FUNCTION; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAM; GENETIC MARKER; GENETICS; GERMANY; HEALTH SURVEY; HEART FAILURE; HEART LEFT VENTRICLE CONTRACTION; HEART LEFT VENTRICLE FILLING; HEART LEFT VENTRICLE HYPERTROPHY; HUMAN; HYPERTENSION; MUSCLE MASS; OBESITY; PHENOTYPE; POPULATION; PREVALENCE; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REVIEW; SEROLOGY; CARDIOVASCULAR RISK; CLINICAL FEATURE; DRUG EFFECT; DRUG MECHANISM; ELECTROCARDIOGRAPHY; HEART FUNCTION; MEDICAL RESEARCH;

ADULT; CARDIOVASCULAR DISEASES; COHORT STUDIES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GERMANY; HUMANS; INCIDENCE; MALE; MIDDLE AGED; PHENOTYPE; POPULATION SURVEILLANCE; REGISTRIES; RISK ASSESSMENT; RISK FACTORS; WORLD HEALTH ORGANIZATION;

EID: 23844445450     PISSN: 09413790     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-858247     Document Type: Review

References (41)

1. Schunkert H, Ingelfinger JR, Hirsch AT et al. Evidence for tissue specific activation of renal angiotensinogen mRNA expression in chronic stable experimental heart failure. J Clin Invest 1992; 90: 1523-1529
2. Schunkert H, Jackson B, Tang SS et al. Distribution and functional significance of cardiac angiotensin converting enzyme in hypertrophied rat hearts. Circulation 1993; 87: 1328-1339
3. Schunkert H, Hense HW, Holmer SR et al. Association between a deletion polymorphism of the angiotensin-converting-enzyme gene and left ventricular hypertrophy. New Engl J Med 1994; 330: 1634-1638
4. Danser AH, Schalekamp MA, Bax WA et al. Angiotensin-converting enzyme in the human heart. Effect of the deletion/insertion polymorphism. Circulation 1995; 92 (6): 1387-1388
5. Muscholl MW, Schunkert H, Muders F et al. Neurohormonal activity and left ventricular geometry in patients with essential arterial hypertension. Am Heart J 1998; 135: 58-66
6. Schunkert H, Hense HW, Muscholl M et al. Associations between circulating components of the renin-angiotensin-aldosterone system and left ventricular mass. Heart 1997; 77: 24-31
7. Schunkert H, Hense HW. Molekulare Genetik kardiovaskulärer Erkrankungen. Dtsch med Wschr 1995; 120: 533-539
8. Lindholm LH, Ibsen H, Dahlof B et al. Cardiovascular morbidity and mortality in patients with diabetes in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol. Lancet 2002; 359 (9311): 1004-1010
9. Muscholl MW, Hense HW, Brockel U et al. Changes in left ventricular structure and function in patients with white coat hypertension: cross sectional survey. BMJ 1998; 317: 565-570
10. Kuch B, Muscholl M, Luchner A et al. Geschlechtsunterschiede in der Beziehung zwischen Übergewicht und Hypertonie mit linksventrikulärer Masse und Hypertrophie. Z Kardiol 1996; 85: 334-342
11. Hense HW, Gneiting B, Muscholl M et al. The associations of body size and body composition with left ventricular mass: impact for indexation in adults. J Am Coll Cardiol 1998; 32: 451-457
12. Kuch B, Hense HW, Gneiting B et al. Body composition and prevalence of left ventricular hypertrophy. Circulation 2000; 102: 405-410
13. Kuch B, Gneiting B, Döring A et al. Indexation of left ventricular mass in adults with a novel approximation for fat free mass. J Hypertens 2001; 19: 135-142
14. Kuch B, Muscholl M, Luchner A et al. Gender specific differences in left ventricular adaptation to obesity and hypertension. J Hum Hypertens 1998; 12: 685-691
15. Hense HW, Schunkert H. Relations of left ventricular mass to fat-free and adipose body mass. Circulation 1999; 100: e145 [electronic pages]
16. Schunkert H, Hense HW, Muscholl M et al. Association of angiotensin converting enzyme activity and arterial blood pressure in a population-based sample. J Hypertens 1996; 14: 571-575
17. Schunkert H, Hense HW, Andus T et al. Relation between dehydroepiandrosterone sulfate and blood pressure levels in a population-based sample. Am J Hypertens 1999; 12 (11 Pt 1): 1140-1143
18. Luchner A, Burnett JC Jr, Jougasaki M et al. Evaluation of brain natriuretic peptide as marker of left ventricular dysfunction and hypertrophy in the population. J Hypertens 2000; 18: 1121-1128
19. Luchner A, Brocket U, Muscholl M et al. Gender-specific differences of cardiac remodeling in subjects with left ventricular dysfunction: a population-based study. Cardiovasc Res 2002; 53: 720-727
20. Luchner A, Hengstenberg C, Lowel H et al. N-terminal pro-brain natriuretic peptide after myocardial infarction: a marker of cardio-renal function. Hypertension 2002; 39(1): 99-104
21. Schunkert H, Danser AH, Hense HW et al. Effects of estrogen replacement therapy on the renin angiotensin system in postmenopausal women. Circulation 1997; 95: 39-45
22. Frohlich M, Schunkert H, Hense HW et al. Effects of hormone replacement therapies on fibrinogen and plasma viscosity in postmenopausal women. Br J Haematol 1998; 100: 577-581
23. Holmer SR, Hense HW, Danser AH et al. Beta-adrenergic blockers lower renin in patients treated with ACE inhibitors and diuretics. Heart 1998; 80: 45-48
24. Luchner A, Burnett JC Jr, Jougasaki M et al. Augmentation of the cardiac natriuretic peptides by beta-receptor antagonism: evidence from a population-based study. J Am Coll Cardiol 1998; 32: 1839-1844
25. Schunkert H, Hense HW, Brockel U et al. Differential effects of antihypertensive drugs on neurohormonal activation: insights from a population-based sample. J Int Med 1998; 244: 109-119
26. Straub RH, Hense HW, Andus T et al. Hormone replacement therapy and interrelation between serum interleukin 6 and body mass index in postmenopausal women: a population-based study. J Clin Endocrinol Metab 2000; 85: 1340-1344
27. Schunkert H, Hense HW, Gimenez-Roqueplo AP et al. The angiotensinogen T235 variant and the use of antihypertensive drugs in a population-based cohort. Hypertension 1997; 29: 628-633
28. Hengstenberg C, Schunkert H, Mayer B et al. Association between a polymorphism in the G protein beta3 subunit gene (GNB3) with arterial hypertension but not with myocardial infarction. Cardiovasc Res 2001; 49: 820-827
29. Jamshidi Y, Montgomery HE, Hense HW et al. Peroxisome proliferator - activated receptor alpha gene regulates left ventricular growth in response to exercise and hypertension. Circulation 2002; 105: 950-955
30. Schunkert H, Hense HW, Döring A et al. Association between a polymorphism in the G protein beta3 subunit gene and lower renin and elevated diastolic blood pressure levels. Hypertension 1998; 32: 510-513
31. Danser AH, Derkx FH, Hense HW et al. Angiotensinogen (M235T) and angiotensinogen-converting enzyme (I/D) polymorphisms in association with plasma renin and prorenin levels. J Hypertens 1998; 16: 1879-1883
32. Schunkert H, Hengstenberg C, Holmer SR et al. Lack of association between a polymorphism of the aldosterone synthase gene and left ventricular structure. Circulation 1999; 99: 2255-2260
33. Hengstenberg C, Holmer SR, Mayer B et al. Evaluation of the aldosterone synthase (CYP11B2) gene polymorphism in patients with myocardial infarction. Hypertension 2000; 35: 704-709
34. Zhang X, Erdmann J, Regitz-Zagrosek V et al. Evaluation of three polymorphisms in the promoter region of the angiotensin II type I receptor gene. J Hypertens 2000; 18: 267-272
35. Sedlacek K, Fischer M, Erdmann J et al. Relation of the G protein beta3-subunit polymorphism with left ventricle structure and function. Hypertension 2002; 40: 162-167
36. Schunkert H, Brockel U, Hengstenberg C et al. Familial predisposition of left ventricular hypertrophy. J Am Coll Cardiol 1999; 33: 1685-1691
37. Schunkert H, Broeckel U, Hense HW et al. Left-ventricular dysfunction. Lancet 1998; 351: 372 [letter]
38. Fischer M, Baessler A, Holmer SR et al. Epidemiology of left ventricular systolic dysfunction in the general population of Germany: results of an echocardiographic study of a large population-based sample. Z Kardiol 2003; 92: 294-302
39. Fischer M, Baessler A, Hense HW et al. Prevalence of left ventricular diastolic dysfunction in the community: Results from a Doppler echocardiographic-based survey of a population sample. Eur Heart J 2003; 24: 320-328
40. Schunkert H, Hense HW. A heart price to pay for anaemia. Nephrol Dial Transplant 2001; 16: 445-448 (editorial)
41. Schunkert H, Koenig W, Brockel U et al. Haematocrit profoundly affects left ventricular diastolic filling as assessed by Doppler echocardiography. J Hypertens 2000; 18: 1483-1488