Influence of HLA-DRB1 alleles and HBV genotypes on interferon-α therapy for chronic hepatitis B

World Journal of Gastroenterology

Volumn 11, Issue 30, 2005, Pages 4753-4757

  Chu, Rui Hai ^a   Ma, Li Xian ^a   Wang, Gang ^a   Shao, Li Hua ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Chronic hepatitis B; HBV genotypes; HLA DRB1 alleles; Interferon therapy

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA INTERFERON; HEPATITIS B(E) ANTIBODY; HEPATITIS B(E) ANTIGEN; HLA DR ANTIGEN; VIRUS DNA;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALLELE; ARTICLE; CHI SQUARE TEST; CHINA; CONTROLLED STUDY; DRUG RESPONSE; FEMALE; GENETIC VARIABILITY; GENOTYPE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; MAJOR CLINICAL STUDY; MALE; PHARMACOGENETICS; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SEROCONVERSION;

EID: 23844439061     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i30.4753     Document Type: Article

References (25)

1. Merican I, Guan R, Amarapukaa D, Alexander MJ, Chutaputti A, Chien RN, Hasnian SS, Leung N, Lesmana L, Phiet PH, Sjalfoellah Noer HM, Sollano J, Sun HS, Xu DZ. Chronic hepatitis B virus infection in Asian countries. J Gastroenterol Hepatol 2000; 15: 1356-1361
2. Olerup O, Zetterquist H. HLADR typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 h: an alternative to serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation. Tissue Antigen 1992; 39: 225-235
3. Naito H, Hayashi S, Abe K. Rapid and specific genotyping system for hepatitis B virus corresponding to six major genotypes by PCR using type-specific primers. J Clin Microbiol 2001; 39: 362-364
4. Wong DK, Cheung AM, O'Rourke K, Naylor CD, Detsky AS, Heathcote J. Effect of alfa-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B. A metaanalysis. Ann Intern Med 1993; 119: 312-323
5. Lindh M, Hannoun C, Horal P, Krogsgaard K. Interpred Study Group. Virological response to interferon therapy of chronic hepatitis B as measured by a highly sensitive assay. J Viral Hepat 2001; 8: 349-357
6. Brunetto MR, Oliveri F, Coco B, Leandro G, Colombatto P, Gorin JM, Bonino F. Outcome of anti-HBe positive chronic hepatitis B in alpha-interferon treated and untreated patients: a long term cohort study. J Hepatol 2002; 36: 263-270
7. Carreno V, Marchllin P, Hadziyannis S, Salmeron J, Diago M, Kitis GE, Vafiadis I, Schalm SW, Zahm F, Manzarbeitia F, Jimenez FJ, Quiroga JA. Retreatment of chronic hepatitis B e antigen-positive patients with recombinant interferon alfa-2a. The european concerted action on viral hepatitis (EUROHEP). Hepatology 1999; 30: 277-282
8. Tatulli I, Francavilla R, Rizzo GL, Vinciguerra V, Ierardi E, Amoruso A, Panella C, Francavilla A. Lamivudine and alpha-interferon in combination long term for precore mutant chronic hepatitis B. J Hepatol 2001; 35: 805-810
9. Shen JJ, Ji Y, Gu XL, Huang RJ, Sun YP. The association of HLA-DRB1*10 with chronic hepatitis B in Chinese patients. Zhonghua Weishengwuxue He Mianyixue Zazhi 1999; 19: 58-59
10. Diepolder HM, Jung MC, Keller E, Schraut W, Gerlach JT, Gruner N, Zachoval R, Hoffmann RM, Schirren CA, Scholz S, Pape GR. A vigorous virus-specific CD4+ T cell response may contribute to the association of HLA-DR13 with viral clearance in hepatitis B. Clin Exp Immunol 1998; 113: 244-251
11. Okamoto H, Tsuda F, Sakugawa H, Sastrosoewignjo RI, Imai M, Miyakawa Y, Mayumi M. Typing hepatitis B virus by homology in nucleotide sequence: comparison of surface antigen subtypes. J Gen Virol 1988; 69(Pt 10): 2575-2583
12. Norder H, Courouce AM, Magnius LO. Complete genomes, phylogenetic relatedness, and structural proteins of six strains of the hepatitis B virus, four of which represent two new genotypes. Virology 1994; 198: 489-503
13. Stuyver L, De Gendt S, Van Geyt C, Zoulim F, Fried M, Schinazi RF, Rossau R. A new genotype of hepatitis B virus: complete genome and phylogenetic relatedness. J Gen Virol 2000; 81 (Pt 1): 67-74
14. Arauz-Ruiz P, Norder H, Robertson BH, Magnius LO. Genotype H: a new Amerindian genotype of hepatitis B virus revealed in Central America. J Gen Virol 2002; 83(Pt 8): 2059-2073
15. Lindh M, Gonzalez JE, Norkrans G, Horal P. Genotyping of hepatitis B virus by restriction pattern analysis of a pre-S amplicon. J Virol Methods 1998; 72: 163-174
16. Swenson PD, Van Geyt C, Alexander WR, Hagan H, Freitag-Koomtz JM, Wilson S, Norder H, Magnius LO, Stuyver L. Hepatitis B virus genotypes and HbsAg subtypes in refugees and injection drug users in the United States determined by LiPA and monoclonal EIA. J Med Virol 2001; 64: 305-311
17. Blitz L, Pujol FH, Swenson PD, Porto L, Atercio R, Araujo M, Costa L, Monsalve DC, Torres JR, Fields HA, Lambert S, Van Geyt C, Norder H, Magnius LO, Echevarria JM, Stuyver L. Antigenic diversity of hepatitis B virus strains of genotype F in Amerindians ans other population groups from Venezuela. J Clin Microbiol 1998; 36: 648-651
18. Kao JH, Chen PJ, Lai MY, Chen DS. Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B. Gastroenterology 2000; 118: 554-559
19. Erhardt A, Reineke U, Blondin D, Gerlich WH, Adams O, Heintges T, Niederau C, Haussinger D. Mutations of the core promoter and response to interferon treatment in chronic replicative hepatitis B. Hepatology 2000; 31: 716-725
20. Wai CT, Chu CJ, Hussain M, Lok AS. HBV genotype B is associated with better response to interferon therapy in HBeAg (+) chronic hepatitis than genotype C. Hepatology 2002; 36: 1425-1430
21. Kao JH, Wu NH, Chen PJ, Lai MY, Chen DS. Hepatitis B genotypes and the response to interferon therapy. J Hepatol 2000; 33: 998-1002
22. Cotrina M, Buti M, Jardi R, Rodriguez-Frias F, Campins M, Esteban R, Guardia J. Study of HLA-II antigens in chronic hepatitis C and B and in acute hepatitis B. Gastroenterol Hepatol 1997; 20: 115-118
23. Liu PB, Xu HW, Wang XL, Li H, Zhuang GH, Wu ZL, Zhang KL. Field epidemiological and experimental study on relationship between genetic factor and non-response or hyporesponse to hepatitis B vaccine. Zhonghua Yixue Zazhi 2000; 113: 547-550
24. Wang C, Tang J, Song W, Lobashevsky E, Wilson CM, Kaslow RA. HLA and cytokine gene polymorphisms are independently associated with responses to hepatitis B vaccination. Hepatology 2004; 39: 978-988
25. Qian Y, Zhang L, Liang XM, Hou JL, Lou KX. Association of immune response to hepatitis B vaccine with HLA-DRB1*02, 07, 09 genes in the population of Han nationality in Guangdong Province. Diyi Junyi Daxue Xuebao 2002; 22: 67-69