The burden of Staphylococcus aureus infections on hospitals in the United States: An analysis of the 2000 and 2001 Nationwide Inpatient Sample database

Archives of Internal Medicine

Volumn 165, Issue 15, 2005, Pages 1756-1761

  Noskin, Gary A ^a,g   Rubin, Robert J ^b   Schentag, Jerome J ^c   Kluytmans, Jan ^d   Hedblom, Edwin C ^e   Smulders, Maartje ^f   Lapetina, Elizabeth ^f   Gemmen, Eric ^f  

^a NORTHWESTERN UNIVERSITY   (United States)

^b GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY AT BUFFALO   (United States)

^d AMPHIA HOSPITAL   (Netherlands)

^e 3M COMPANY   (United States)

^f IQVIA   (United States)

^g NORTHWESTERN MEMORIAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGE DISTRIBUTION; ARTICLE; COMORBIDITY; CONTROLLED STUDY; DATA BASE; FEMALE; HOSPITAL CARE; HOSPITAL CHARGE; HOSPITAL DISCHARGE; HOSPITAL PATIENT; HUMAN; LENGTH OF STAY; MALE; MORTALITY; PRIORITY JOURNAL; RACE DIFFERENCE; RETROSPECTIVE STUDY; RISK FACTOR; SEX DIFFERENCE; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; UNITED STATES;

AGE FACTORS; COST OF ILLNESS; FEMALE; HOSPITAL CHARGES; HOSPITAL MORTALITY; HUMANS; LENGTH OF STAY; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; STAPHYLOCOCCAL INFECTIONS; UNITED STATES;

EID: 23744476740     PISSN: 00039926     EISSN: None     Source Type: Journal    
DOI: 10.1001/archinte.165.15.1756     Document Type: Article

References (31)

1. National Nosocomial Infections Surveillance System. National Nosocomial Infections Surveillance (NNIS) System Report, Data Summary From October 1986-April 1998. Atlanta, Ga: US Dept of Health and Human Services; 1998:10.
2. Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR. Guideline for prevention of surgical site infection, 1999: Hospital Infection Control Practices Advisory Committee. Infect Control Hosp Epidemiol. 1999;20:250-278.
3. National Nosocomial Infections Surveillance System. National Nosocomial Infections Surveillance (NNIS) System report, data summary from January 1992 through June 2003, issued August 2003. Am J Infect Control. 2003;31:481-498.
4. Rubin RJ, Harrington CA, Poon A, Dietrich K, Greene JA, Moiduddin A. The economic impact of Staphylococcus aureus infection in New York City hospitals. Emerg Infect Dis. 1999;5:9-17.
5. Green JW, Wenzel RP. Postoperative wound infection: a controlled study of the increased duration of hospital stay and direct cost of hospitalization. Ann Surg. 1977;185:264-268.
6. Nelson RM, Dries DJ. The economic implications of infection in cardiac surgery. Ann Thorac Surg. 1986;42:240-246.
7. Orsi GB, Di Stefano L, Noah N. Hospital-acquired, laboratory-confirmed bloodstream infection: increased hospital stay and direct costs. Infect Control Hosp Epidemiol. 2002;23:190-197.
8. Whitehouse JD, Friedman ND, Kirkland KB, Richardson WJ, Sexton DJ. The impact of surgical-site infections following orthopedic surgery at a community hospital and a university hospital: adverse quality of life, excess length of stay, and extra cost. Infect Control Hosp Epidemiol. 2002;23:183-189.
9. Boyce JM, Potter-Bynoe G, Dziobek L. Hospital reimbursement patterns among patients with surgical wound infections following open heart surgery. Infect Control Hosp Epidemiol. 1990;11:89-93.
10. Kirkland KB, Briggs JP, Trivette SL, Wilkinson WE, Sexton DJ. The impact of surgical-site infections in the 1990s: attributable mortality, excess length of hospitalization, and extra costs. Infect Control Hosp Epidemiol. 1999;20:725-730.
11. McGarry SA, Engemann JJ, Schmader K, Sextom DJ, Kaye KS. Surgical-site infection due to Staphylococcus aureus among elderly patients: mortality, duration of hospitalization, and cost. Infect Control Hosp Epidemiol. 2004;25:461-467.
12. Agency for Healthcare Research and Quality. Overview of the Nationwide Inpatient Sample (NIS). Available at www.hcup-us.ahrq.gov/nisoverview.jsp. Accessed May 16, 2005.
13. Healthcare Cost and Utilization Project. Overview of the HCUP Nationwide Inpatient Sample (NIS) 2001. Rockville, MD: Agency for Healthcare Research and Quality; 2001:6.
14. Frazier CB, Ericson B, Miller S, Spetsas J, Turner K, eds. International Classification of Diseases, 9th Revision, Clinical Modification. Vol 1. 6th ed. Salt Lake City, Utah: Medicode; 2000:3-327.
15. Leske MC, Sorenson AA, Zimmer JG. Discrepancies between admission and discharge diagnoses in a university hospital. Med Care. 1978;16:740-748.
16. Gujarati DN. Basic Econometrics. 4th ed. Boston, Mass: McGraw-Hill Higher Education; 2003:248-333, 335-504.
17. Little R, Milliken G, Stroup W, Wolfinger R. SAS System for Mixed Models. Cary, NC: SAS Institute Inc; 1996.
18. Zhan C, Miller MR. Excess length of stay, charges, and mortality attributable to medical injuries during hospitalization. JAMA. 2003;290:1868-1874.
19. US Bureau of the Census. Statistical Abstract of the United States: 2003. 123rd ed. Washington, DC: US Bureau of the Census; 2003:477. Table 715.
20. Perl TM, Cullen JJ, Wenzel RP, et al. Intranasal mupirocin to prevent postoperative S aureus infections. N Engl J Med. 2002;346:1871-1877.
21. Simborg DW. DRG creep: a new hospital-acquired disease. N Engl J Med. 1981;304:1602-1604.
22. Hsia D, Krushat WM, Fagan AB, Tebbutt JA, Kusserow RP. Accuracy of diagnosis coding for Medicare patients under the Prospective Payment System. N Engl J Med. 1988;318:352-355.
23. Kaye KS, Engemann JJ, Mozaffari E, Carmeli Y. Reference group choice and antibiotic resistance outcomes. Emerg Infect Dis. 2004;10:1125-1128.
24. Sharma M, Berriel-Cass D, Baran J. Sternal surgical-site infection following coronary artery bypass graft: prevalence, microbiology, and complications. Infect Control Hosp Epidemiol. 2004;25:468-471.
25. Boelaert JR, De Baere YA, Geernaert MA, Godard CA, Van Landuyt HW. The use of nasal mupirocin ointment to prevent Staphylococcus aureus bacteraemias in haemodialysis patients: an analysis of cost-effectiveness. J Hosp Infect. 1991;19(suppl B):41-46.
26. Kluytmans JA, Mouton JW, VandenBergh MF, et al. Reduction of surgical-site infections in cardiothoracic surgery by elimination of nasal carriage of Staphylococcus aureus. Infect Control Hosp Epidemiol. 1996;17:780-785.
27. Kluytmans JA, Manders MJ, van Bommel E, Verbrugh H. Elimination of nasal carriage of Staphylococcus aureus in hemodialysis patients. Infect Control Hosp Epidemiol. 1996;17:793-797.
28. Yano M, Doki Y, Inoue M, Tsujinaka T, Shiozaki H, Monden M. Preoperative intranasal mupirocin ointment significantly reduces postoperative infection with Staphylococcus aureus in patients undergoing upper gastrointestinal surgery. Surg Today. 2000;30:16-21.
29. Cimochowski GE, Harostock MD, Brown R, Bernardi M, Alonzo N, Coyle K. Intranasal mupirocin reduces sternal wound infection after open heart surgery in diabetics and nondiabetics. Ann Thorac Surg. 2001;71:1572-1579.
30. Kluytmans J, van Belkum A, Verbugh H. Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks. Clin Microbiol Rev. 1997;10:505-520.
31. Boelaert JR, Van Landuyt HW, Godard CA, Daneels RF, Shurgers ML, Matthys EG. Nasal mupirocin ointment decreases the incidence of Staphylococcus aureus bacteraemias in haemodialysis patients. Nephrol Dial Transplant. 1993;8:235-239.