Possible role of mechano-sensors and the change of relative location of cell organelles in microgravity effects on cells

Advances in the Astronautical Sciences

Volumn 117, Issue , 2004, Pages 845-849

  Zhuang, Fengyuan ^a  

^a BEIHANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BONE; CELLS; EARTH (PLANET); FUNCTIONS; MICROGRAVITY PROCESSING; PHYSIOLOGICAL MODELS;

DIRECT SENSING; MECHANO-SENSORS; ORGANELLES; OSTEOCYTE;

CHEMICAL SENSORS;

EID: 23744473442     PISSN: 00653438     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (7)

1. S. C. Cowin "On Mechanosensation in Bone Under Microgravity", Bone Vol. 22, No.5, Supplement. 119S-125S.
2. G. Carmeliet, G. Nys, and R. Bouillon "Differentiation of human osteoblastic cell (MG-63) in vitro is decreased under microgravity condition", Proceedings of the Sixth European Symposium on life Sciences Research in Space. ESA SP-390: 279-282; 1996.
3. Y. Kumei, H. Shimokawa, H. Katano, E. Hara, H. Akiyama, M. Hirano, C. Mukai, S. Nagaoka, P. A. Whitson, and C. F. Sams "Microgravity induces prostaglandin E2 and interleukin-6 production in normal rat osteoblasts: Role in bone demineralization", J Biotechnol Vol. 47, 1996, 313-324.
4. E. H. Burger and J. Klein-Nulend "Microgravity and Bone Cell Mechanosensitivity", Bone Vol. 22, No.5 Supplement 1998, 127S-130S.
5. S. Chien "Roles of Flow Mechanics in Vascular Cell Biology in Health and Disease" Introduction to Bioengineering, Edited by Y. C. Fung, World Scientific Publishing Co., 1-12, 2001.
6. S. E. Chesla, P. Selvaraj, and C. Zhu, "Measuring Two-Dimension Receptor-Ligand Binding Kinetics by Micropipette", Biophys. J., Vol. 75, 1998, 1553-1572.
7. J. Tabony and D. Job, "Gravitational Symmetry Breaking in Microtubular Dissipative Structures", Proc Natl Acad Sci USA Vol. 89, 1992, 6948-6952.