Detection of K-ras mutated at codon 12 with a modified PCR-RFLP technique

Progress in Biochemistry and Biophysics

Volumn 24, Issue 4, 1997, Pages 378-

  Xiao, Shangxi ^a   Wu, Lin ^a   Wang, Daobin ^a   Hu, Jiegui ^a   Liu, Huaping ^a   Zheng, Bing ^a   Zhang, Jun ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Mutation; Polymerase chain reaction; Ras gene

Indexed keywords

EID: 23744464844     PISSN: 10003282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

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2. Sidransky D, Tokino T, Hamilton S R et al. Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors. Science, 1992, 256 (5053): 102-105
3. Kondo H, Sugano K, Fukayama N et al. Detection of point mutations in the K-ras oncogene at codon 12 in pure pancreatic juice for diagnosis of pancreatic carcinoma. Cancer, 1994, 73 (6): 1589-1594
4. Levi S, Urban-Ispizua A, Gill R et al. Multiple K-ras codon 12 mutations in chologangiocarcinomas demonstrated with a sensitive polymerase chain reaction technique. Cancer Res, 1991, 51: 3497-3502
5. Kashii T, Mizushina Y, Monno S et al. Gene analysis of K-, H-ras, p53, and retinoblastoma susceptibility genes in human lung cancer cell lines by the polymerase reaction/single-strand conformation polymorphism method. J Cancer Res, Clin Oncol, 1994, 120: 143-148
6. Rodenhuis S, Slebos R J. Clinical significance of ras oncogene activation in human lung cancer. Cancer Res, 1992, 52: 2665s-2669s