A randomized trial comparing 1 mg of oral vitamin K with no treatment in the management of warfarin-associated coagulopathy in patients with mechanical heart valves [2]

Journal of the American College of Cardiology

Volumn 46, Issue 4, 2005, Pages 732-733

  Ageno, Walter ^a   Garcia, David ^b   Silingardi, Mauro ^b   Galli, Matteo ^b   Crowther, Mark ^b  

^a OSPEDALE DI CIRCOLO   (Italy)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

PHYTOMENADIONE; WARFARIN;

ADULT; AGED; ANTICOAGULANT THERAPY; BLEEDING; BLOOD CLOTTING DISORDER; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG SAFETY; FEMALE; HEART VALVE PROSTHESIS; HUMAN; INTERNATIONAL NORMALIZED RATIO; LETTER; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; THROMBOEMBOLISM; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; ANTICOAGULANTS; BLOOD COAGULATION DISORDERS; FEMALE; HEART VALVE PROSTHESIS; HUMANS; INTERNATIONAL NORMALIZED RATIO; MALE; MIDDLE AGED; VITAMIN K; WARFARIN;

EID: 23644461917     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2005.05.022     Document Type: Letter

References (5)

1. E.M. Hylek, Y.C. Chang, S.J. Skates, R.A. Hughes, D.E. Singer Prospective study of the outcomes of ambulatory patients with excessive warfarin anticoagulation Arch Intern Med 160 2000 1612 1617
2. F.J.M. van der Meer, F.R. Rosendaal, J.P. Vandenbroucke, E. Briet Bleeding complications in oral anticoagulant therapy An analysis of risk factors Arch Intern Med 153 1995 1557 1562
3. V. Pengo, A. Banzato, E. Garelli, A. Zasso, A. Biasiolo Reversal of excessive effect of regular anticoagulation: low oral dose of phytonadione (vitamin K1) compared with warfarin discontinuation Blood Coag Fibrinol 4 1993 739 741
4. M.A. Crowther, J. Julian, J.D. Douketis Treatment of warfarin-associated coagulopathy with oral vitamin K: a randomized clinical trial Lancet 356 2000 1551 1553
5. M.A. Crowther, D. Donovan, L. Harrison, J. McGinnis, J. Ginsberg Low-dose oral vitamin K reliably reverses over-anticoagulation due to warfarin Thromb Haemost 79 1998 1116 1118