Relaxin as an additional protective substance in preserving and reperfusion solution for liver transplantation, shown in a model of isolated perfused rat liver

Annals of the New York Academy of Sciences

Volumn 1041, Issue , 2005, Pages 434-440

  Boehnert, Markus U ^a   Hilbig, Heidegard ^b   Armbruster, Franz P ^c  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c IMMUNDIAGNOSTIK AG   (Germany)

Author keywords

Ischemia; Liver; Relaxin; Reperfusion injury; Transplantation

Indexed keywords

HUMAN RELAXIN 2; MALONALDEHYDE; MYELOPEROXIDASE; RELAXIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CELL DAMAGE; CONFERENCE PAPER; CONTROLLED STUDY; DISEASE SIMULATION; ENZYME ACTIVITY; IMMUNOHISTOCHEMISTRY; ISOLATED LIVER; LIVER PERFUSION; LIVER PRESERVATION; LIVER PROTECTION; LIVER TRANSPLANTATION; MALE; NONHUMAN; QUANTITATIVE ANALYSIS; RAT; REPERFUSION INJURY; VASODILATATION;

EID: 23644454431     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1282.065     Document Type: Conference Paper

References (11)

1. PEGG et al. 1982. Organ Preservation: basic and applied aspects. In Boston, Lancaster, the Hague, MTP Pressing Limited;
2. HOCHACHKA, P.W. 1986. Defense strategies against hypoxia and hypothermia. Science 231: 234-241.
3. BELZER, F.O. & J.H. SOUTHARD. 1988. Principles of solid-organ preservation by cold storage. Transplantation 45: 673-676.
4. SINGER, D. & H.J. BRETSCHNEIDER. 1990. Metabolic reduction in hypothermia: pathophysiological problems and natural examples. Part 1. Thorac. Cardiovasc. Surg. 38: 205-211.
5. STARZL, T.E. et al. 1963. Surg. Gynecol. Obstet. 117: 659-676.
6. PIENAAR, B.H., G.N. STAPLETON, M. BRACHER, et al. 1991. Six-hour porcine liver storage without flushing or perfusion. Transplantation 52: 38-43.
7. Belzer, P.O. & J.H. Southard. 1988. Principles of solid-organ preservation by cold storage. Transplantation 45: 673-676.
8. JAMIESON, N.V. et al. 1989. Eur. J. Gastroenterol. Hepatol. 1: 83-86.
9. GUBERNATIS, G., R. PICHLMAYR, P. LAMESCH, et al. 1990. HTK-solution (Bretschneider) for human liver transplantation. First clinical experiences. Langenbecks Arch. Chir. 375: 66-70.
10. ERHARD, J., R. LANGE, R. SCHERER, et al. 1994. Comparison of histidine-tryptophan-ketoglutarate (HTK) solution versus University of Wisconsin (UW) solution for organ preservation in human liver transplantation. A prospective, randomized study. Transpl. Int. 7: 177-181.
11. BANI, D., E. MASINI, M.G. BELL, et al. 1998. Relaxin protects against myocardial injury caused by ischemia and reperfusion in rat heart. Am. J. Pathol. 152: 1367-1376.