Immunohistostaining of hepatitis C virus non-structural protein 4 in ependymocytes of uninfected mice: An antigenic mimicry?

Scandinavian Journal of Gastroenterology

Volumn 40, Issue 8, 2005, Pages 992-994

  Francavilla, Ruggiero ^a   Margiotta, Marcella ^a   Marangi, Stefania ^a   Burattini, Osvaldo ^a   Francavilla, Antonio ^a   Panella, Carmine ^b   Ierardi, Enzo ^b  

^a UNIVERSITY OF BARI   (Italy)

^b UNIVERSITY OF FOGGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS PROTEIN;

ANIMAL CELL; ANTIGENICITY; ARTICLE; BRAIN SIZE; CONTROLLED STUDY; CYTOPLASM; EPENDYMA CELL; HEPATITIS C VIRUS; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LIVER BIOPSY; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANTIBODIES, MONOCLONAL; CYTOPLASM; EPENDYMA; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED BALB C; MOLECULAR MIMICRY; VIRAL NONSTRUCTURAL PROTEINS;

EID: 23644447179     PISSN: 00365521     EISSN: None     Source Type: Journal    
DOI: 10.1080/00365520510023486     Document Type: Article

References (14)

1. Forton DM, Taylor-Robinson SD, Thomas HC. Cerebral dysfunction in chronic hepatitis C infection. J Viral Hepat 2003;10:81-6.
2. Kramer L, Bauer E, Funk G, Hofer H, Jessner W, Steindl-Munda P, et al. Subclinical impairment of brain function in chronic hepatitis C infection. J Hepatol 2002;37:349-54.
3. Main J, Foster GR, Thomas HC, Taylor-Robinson SD. Evidence for a cerebral effect of the hepatitis C virus. Lancet 2001;358:38-9.
4. Laskus T, Radkowski M, Bednarska A, Wilkinson J, Adair D, Nowicki M, et al. Detection and analysis of hepatitis C virus sequences in cerebrospinal fluid. J Virol 2002;76:10064-8.
5. Vargas HE, Laskus T, Radkowski M, Wilkinson J, Balan V, Douglas DD, et al. Detection of hepatitis C virus sequences in brain tissue obtained in recurrent hepatitis C after liver transplantation. Liver Transpl 2002;8:1014-9.
6. Wucherpfenning KW, Strominger JL. Molecular mimicry in T cell mediated autoimmunity viral peptides activates human T-cell clones for myelin basic protein. Cell 1995;80:695-705.
7. Strassburg CP, Vogel A, Manns MP. Autoimmunity and hepatitis C. In: "Autoimmunity reviews 2". Elsevier: Science Direct; 2003. pp 322-31.
8. Gale M Jr, Beard MR. Molecular clones of hepatitis C virus: applications to animal models. ILAR J 2001;42:139-51.
9. Francavilla A, Ierardi E, Francavilla R, Principi M, Gentile A, Margiotta M, et al. Immunohistochemical detection of Helicobacter pylori vacuolating cytotoxin in the hepatocytes of patients with isolated hypertransaminasaemia. Ital J Gastroterol Hepatol 1999;31:669-74.
10. Pow CS. In: Ward JM, Mahler JF, Maronpot RR, Sundberg JP, editors. Pathology of genetically engineered mice. Iowa, USA: Iowa State University Press; 2000. pp 23-32.
11. Nayak NC, Sathar SA. Immunohistochemical detection of hepatitis C virus antigen in paraffin embedded liver biopsies from patients with chronic liver disease. Acta Histochem 1999;101:409-19.
12. Laudin M, Monne M, Widell A, Von Heijne G, Persson MA. Topology of the membrane associated hepatitis C virus protein NS4B. J Virol 2003;77:5428-38.
13. Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci USA 2002;99:16899-903.
14. Nacher J, Ramirez C, Palop JJ, Molowny A, Luis de la Iglesia JA, Lopez-Garcia C. Radial glia and cell debris removal during lesion-regeneration of the lizard medial cortex. Histol Histopathol 1999;14:89-101.