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Volumn 1041, Issue , 2005, Pages 1-7

Relaxin research in the postgenomic era

Author keywords

INSL3; LGR7; LGR8; Oocyte maturation; Relaxin; Testicular spermatogenesis

Indexed keywords

CYCLIC AMP; FOLLITROPIN RECEPTOR; G PROTEIN COUPLED RECEPTOR; GONADOTROPIN; LEUCINE RICH REPEAT CONTAINING G PROTEIN COUPLED RECEPTOR 7; LEUCINE RICH REPEAT CONTAINING G PROTEIN COUPLED RECEPTOR 8; LIGAND; LUTEINIZING HORMONE; LUTEINIZING HORMONE RECEPTOR; PEPTIDE HORMONE; PROTEIN INSL3; RELAXIN; RELAXIN 3; THYROTROPIN RECEPTOR; UNCLASSIFIED DRUG;

EID: 23644444471     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1282.001     Document Type: Conference Paper
Times cited : (13)

References (32)
  • 1
    • 0034463310 scopus 로고    scopus 로고
    • Discovering new hormones, receptors, and signaling mediators in the genomic era
    • HSU, S.Y. & A.J. HSUEH. 2000. Discovering new hormones, receptors, and signaling mediators in the genomic era. Mol. Endocrinol. 14: 594-604.
    • (2000) Mol. Endocrinol. , vol.14 , pp. 594-604
    • Hsu, S.Y.1    Hsueh, A.J.2
  • 2
    • 0033310863 scopus 로고    scopus 로고
    • Cloning of two novel mammalian paralogs of relaxin/insulin family proteins and their expression in testis and kidney
    • HSU, S.Y. 1999. Cloning of two novel mammalian paralogs of relaxin/insulin family proteins and their expression in testis and kidney. Mol. Endocrinol. 13: 2163-2174.
    • (1999) Mol. Endocrinol. , vol.13 , pp. 2163-2174
    • Hsu, S.Y.1
  • 3
    • 0037059750 scopus 로고    scopus 로고
    • Human relaxin gene 3 (H3) and the equivalent mouse relaxin (M3) gene. Novel members of the relaxin peptide family
    • BATHGATE, R.A., C.S. SAMUEL, T.C. BURAZIN, et al. 2002. Human relaxin gene 3 (H3) and the equivalent mouse relaxin (M3) gene. Novel members of the relaxin peptide family. J. Biol. Chem. 277: 1148-1157.
    • (2002) J. Biol. Chem. , vol.277 , pp. 1148-1157
    • Bathgate, R.A.1    Samuel, C.S.2    Burazin, T.C.3
  • 4
    • 0000437998 scopus 로고    scopus 로고
    • Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seven-transmembrane region
    • HSU, S.Y., S.G. LIANG & A.J. HSUEH. 1998. Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seven-transmembrane region. Mol. Endocrinol. 12: 1830-1845.
    • (1998) Mol. Endocrinol. , vol.12 , pp. 1830-1845
    • Hsu, S.Y.1    Liang, S.G.2    Hsueh, A.J.3
  • 5
    • 0034464024 scopus 로고    scopus 로고
    • The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): Identification of LGR6 and LGR7 and the signaling mechanism for LGR7
    • HSU, S.Y., M. KUDO, T. CHEN, et al. 2000. The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7. Mol. Endocrinol. 14: 1257-1271.
    • (2000) Mol. Endocrinol. , vol.14 , pp. 1257-1271
    • Hsu, S.Y.1    Kudo, M.2    Chen, T.3
  • 6
    • 0033304740 scopus 로고    scopus 로고
    • Targeted disruption of the Ins13 gene causes bilateral cryptorchidism
    • ZIMMERMANN, S., G. STEDING, J.M. EMMEN, et al. 1999. Targeted disruption of the Ins13 gene causes bilateral cryptorchidism. Mol. Endocrinol. 13: 681-691.
    • (1999) Mol. Endocrinol. , vol.13 , pp. 681-691
    • Zimmermann, S.1    Steding, G.2    Emmen, J.M.3
  • 7
    • 0032989104 scopus 로고    scopus 로고
    • Cryptorchidism in mice mutant for Ins13
    • NEF, S. & L.F. PARADA. 1999. Cryptorchidism in mice mutant for Ins13. Nat. Genet. 22: 295-299.
    • (1999) Nat. Genet. , vol.22 , pp. 295-299
    • Nef, S.1    Parada, L.F.2
  • 8
    • 0035019760 scopus 로고    scopus 로고
    • A transgenic insertion causing cryptorchidism in mice
    • OVERBEEK, P.A., I.P. GORLOV, R.W. SUTHERLAND, et al. 2001. A transgenic insertion causing cryptorchidism in mice. Genesis 30: 26-35.
    • (2001) Genesis , vol.30 , pp. 26-35
    • Overbeek, P.A.1    Gorlov, I.P.2    Sutherland, R.W.3
  • 9
    • 0037169071 scopus 로고    scopus 로고
    • Activation of orphan receptors by the hormone relaxin
    • HSU, S.Y., K. NAKABAYASHI, S. NISHI, et al. 2002. Activation of orphan receptors by the hormone relaxin. Science 295: 671-674.
    • (2002) Science , vol.295 , pp. 671-674
    • Hsu, S.Y.1    Nakabayashi, K.2    Nishi, S.3
  • 10
    • 0037200034 scopus 로고    scopus 로고
    • INSL3/Leydig insulin-like peptide activates the LGR8 receptor important in testis descent
    • KUMAGAI, J., S.Y. HSU, H. MATSUMI, et al. 2002. INSL3/Leydig insulin-like peptide activates the LGR8 receptor important in testis descent. J. Biol. Chem. 277: 31283-31286.
    • (2002) J. Biol. Chem. , vol.277 , pp. 31283-31286
    • Kumagai, J.1    Hsu, S.Y.2    Matsumi, H.3
  • 11
    • 0037424265 scopus 로고    scopus 로고
    • H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2
    • SUDO, S., J. KUMAGAI, S. NISHI, et al. 2003. H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2. J. Biol. Chem. 278: 7855-7862.
    • (2003) J. Biol. Chem. , vol.278 , pp. 7855-7862
    • Sudo, S.1    Kumagai, J.2    Nishi, S.3
  • 12
    • 0030852475 scopus 로고    scopus 로고
    • Derivation of functional antagonists using N-terminal extracellular domain of gonadotropin and thyrotropin receptors
    • OSUGA, Y., M. KUDO, A. KAIPIA, et al. 1997. Derivation of functional antagonists using N-terminal extracellular domain of gonadotropin and thyrotropin receptors. Mol. Endocrinol. 11: 1659-1668.
    • (1997) Mol. Endocrinol. , vol.11 , pp. 1659-1668
    • Osuga, Y.1    Kudo, M.2    Kaipia, A.3
  • 13
    • 0042836864 scopus 로고    scopus 로고
    • New insights into the evolution of the relaxin-LGR signaling system
    • HSU, S.Y. 2003. New insights into the evolution of the relaxin-LGR signaling system. Trends Endocrinol. Metab. 14: 303-309.
    • (2003) Trends Endocrinol. Metab. , vol.14 , pp. 303-309
    • Hsu, S.Y.1
  • 14
    • 10744224962 scopus 로고    scopus 로고
    • Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein-coupled receptor GPCR135
    • LIU, C., E. ERISTE, S. SUTTON, et al. 2003. Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein-coupled receptor GPCR135. J. Biol. Chem. 278: 50754-50764.
    • (2003) J. Biol. Chem. , vol.278 , pp. 50754-50764
    • Liu, C.1    Eriste, E.2    Sutton, S.3
  • 15
    • 0346118862 scopus 로고    scopus 로고
    • Identification of relaxin-3/INSL7 as a ligand for GPCR142
    • LIU, C., J. CHEN, S. SUTTON, et al. 2003. Identification of relaxin-3/INSL7 as a ligand for GPCR142. J. Biol. Chem. 278: 50765-50770.
    • (2003) J. Biol. Chem. , vol.278 , pp. 50765-50770
    • Liu, C.1    Chen, J.2    Sutton, S.3
  • 16
    • 0344873145 scopus 로고    scopus 로고
    • Identification and characterisation of GPR100 as a novel human G-protein-coupled bradykinin receptor
    • BOELS, K. & H.C. SCHALLER. 2003. Identification and characterisation of GPR100 as a novel human G-protein-coupled bradykinin receptor. Br. J. Pharmacol. 140: 932-938.
    • (2003) Br. J. Pharmacol. , vol.140 , pp. 932-938
    • Boels, K.1    Schaller, H.C.2
  • 17
    • 0027365039 scopus 로고
    • Cloning of a cDNA for a novel insulin-like peptide of the testicular Leydig cells
    • ADHAM, I.M., E. BURKHARDT, M. BENAHMED, et al. 1993. Cloning of a cDNA for a novel insulin-like peptide of the testicular Leydig cells. J. Biol. Chem. 268: 26668-26672.
    • (1993) J. Biol. Chem. , vol.268 , pp. 26668-26672
    • Adham, I.M.1    Burkhardt, E.2    Benahmed, M.3
  • 18
  • 19
    • 0032726383 scopus 로고    scopus 로고
    • Structure and expression of the rat relaxin-like factor (RLF) gene
    • SPIESS, A.N., M. BALVERS, M. TENA-SEMPERE, et al. 1999. Structure and expression of the rat relaxin-like factor (RLF) gene. Mol. Reprod. Dev. 54: 319-325.
    • (1999) Mol. Reprod. Dev. , vol.54 , pp. 319-325
    • Spiess, A.N.1    Balvers, M.2    Tena-Sempere, M.3
  • 20
    • 0029908314 scopus 로고    scopus 로고
    • Relaxin-like factor gene is highly expressed in the bovine ovary of the cycle and pregnancy: Sequence and messenger ribonucleic acid analysis
    • BATHGATE, R., M. BALVERS, N. HUNT, et al. 1996. Relaxin-like factor gene is highly expressed in the bovine ovary of the cycle and pregnancy: sequence and messenger ribonucleic acid analysis. Biol. Reprod. 55: 1452-1457.
    • (1996) Biol. Reprod. , vol.55 , pp. 1452-1457
    • Bathgate, R.1    Balvers, M.2    Hunt, N.3
  • 21
    • 0036200191 scopus 로고    scopus 로고
    • Ovulation: New dimensions and new regulators of the inflammatory-like response
    • RICHARDS, J.S., D.L. RUSSELL. S. OCHSNER, et al. 2002. Ovulation: new dimensions and new regulators of the inflammatory-like response. Annu. Rev. Physiol. 64: 69-92.
    • (2002) Annu. Rev. Physiol. , vol.64 , pp. 69-92
    • Richards, J.S.1    Russell, D.L.2    Ochsner, S.3
  • 22
    • 0034453103 scopus 로고    scopus 로고
    • Initial and cyclic recruitment of ovarian follicles
    • MCGEE, E.A. & A.J. HSUEH. 2000. Initial and cyclic recruitment of ovarian follicles. Endocr. Rev. 21: 200-214.
    • (2000) Endocr. Rev. , vol.21 , pp. 200-214
    • McGee, E.A.1    Hsueh, A.J.2
  • 23
    • 0020503375 scopus 로고
    • Gonadotrophin receptors: Correlates with normal and pathological functions of the human ovary and testis
    • HUHTANIEMI, I.T. 1983. Gonadotrophin receptors: correlates with normal and pathological functions of the human ovary and testis. Clin. Endocrinol. Metab. 12: 117-132.
    • (1983) Clin. Endocrinol. Metab. , vol.12 , pp. 117-132
    • Huhtaniemi, I.T.1
  • 24
    • 0036377906 scopus 로고    scopus 로고
    • The expression of the follicle-stimulating hormone receptor in spermatogenesis
    • HECKERT, L.L. & M.D. GRISWOLD. 2002. The expression of the follicle-stimulating hormone receptor in spermatogenesis. Recent Prog. Horm. Res. 57: 129-148.
    • (2002) Recent Prog. Horm. Res. , vol.57 , pp. 129-148
    • Heckert, L.L.1    Griswold, M.D.2
  • 27
    • 0018222043 scopus 로고
    • Morphological and quantitative analysis of spermatogonia in mouse testes using whole mounted seminiferous tubules. I. The normal testes
    • HUCKINS, C. & E.F. OAKBERG. 1978. Morphological and quantitative analysis of spermatogonia in mouse testes using whole mounted seminiferous tubules. I. The normal testes. Anat. Rec. 192: 519-528.
    • (1978) Anat. Rec. , vol.192 , pp. 519-528
    • Huckins, C.1    Oakberg, E.F.2
  • 28
    • 0027173161 scopus 로고
    • Hormonal control of apoptotic cell death in the testis: Gonadotropins and androgens as testicular cell survival factors
    • TAPANAINEN, J.S., J.L. TILLY, K.K. VIHKO, et al. 1993. Hormonal control of apoptotic cell death in the testis: gonadotropins and androgens as testicular cell survival factors. Mol. Endocrinol. 7: 643-650.
    • (1993) Mol. Endocrinol. , vol.7 , pp. 643-650
    • Tapanainen, J.S.1    Tilly, J.L.2    Vihko, K.K.3
  • 29
    • 0023110032 scopus 로고
    • The effect of hypoxanthine on mouse oocyte growth and development in vitro: Maintenance of meiotic arrest and gonadotropin-induced oocyte maturation
    • EPPIG, J.J. & S.M. DOWNS. 1987. The effect of hypoxanthine on mouse oocyte growth and development in vitro: maintenance of meiotic arrest and gonadotropin-induced oocyte maturation. Dev. Biol. 119: 313-321.
    • (1987) Dev. Biol. , vol.119 , pp. 313-321
    • Eppig, J.J.1    Downs, S.M.2
  • 30
    • 0028945656 scopus 로고
    • Chemical structure of sterols that activate oocyte meiosis
    • BYSKOV, A.G., C.Y. ANDERSEN, L. NORDHOLM, et al. 1995. Chemical structure of sterols that activate oocyte meiosis. Nature 374: 559-562.
    • (1995) Nature , vol.374 , pp. 559-562
    • Byskov, A.G.1    Andersen, C.Y.2    Nordholm, L.3
  • 31
    • 0028843116 scopus 로고
    • Interactions between germ cells and Sertoli cells in the testis
    • GRISWOLD, M.D. 1995. Interactions between germ cells and Sertoli cells in the testis. Biol. Reprod. 52: 211-216.
    • (1995) Biol. Reprod. , vol.52 , pp. 211-216
    • Griswold, M.D.1
  • 32
    • 2442485845 scopus 로고    scopus 로고
    • Paracrine regulation of mammalian oocyte maturation and male germ cell survival
    • KAWAMURA, K., J. KUMAGAI, S. SUDO, et al. 2004. Paracrine regulation of mammalian oocyte maturation and male germ cell survival. Proc. Natl. Acad. Sci. USA 101: 7323-7328.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 7323-7328
    • Kawamura, K.1    Kumagai, J.2    Sudo, S.3


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