-
1
-
-
0031001720
-
Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study
-
Murray, C.J. and Lopez, A.D. (1997) Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. Lancet 349, 1498-1504
-
(1997)
Lancet
, vol.349
, pp. 1498-1504
-
-
Murray, C.J.1
Lopez, A.D.2
-
2
-
-
0032696013
-
Effect of high dose inhaled steroid on cells, cytokines, and proteases in induced sputum in chronic obstructive pulmonary disease
-
Culpitt, S.V. et al. (1999) Effect of high dose inhaled steroid on cells, cytokines, and proteases in induced sputum in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 160, 1635-1639
-
(1999)
Am. J. Respir. Crit. Care Med.
, vol.160
, pp. 1635-1639
-
-
Culpitt, S.V.1
-
3
-
-
85030742208
-
An in vitro model of full-thickness human airway epithelium (EpiAirway-FT) for study of epithelium/matrix interactions
-
Hayden, P.J. et al. (2004) An in vitro model of full-thickness human airway epithelium (EpiAirway-FT) for study of epithelium/matrix interactions. Am. J. Respir. Crit. Care Med. 169, A671
-
(2004)
Am. J. Respir. Crit. Care Med.
, vol.169
-
-
Hayden, P.J.1
-
4
-
-
1942504217
-
Macrophage phagocytosis of apoptotic neutrophils is compromised by matrix proteins modified by cigarette smoke and lipid peroxidation products
-
Kirkham, P.A. et al. (2004) Macrophage phagocytosis of apoptotic neutrophils is compromised by matrix proteins modified by cigarette smoke and lipid peroxidation products. Biochem. Biophys. Res. Commun. 318, 32-37
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.318
, pp. 32-37
-
-
Kirkham, P.A.1
-
5
-
-
0242441578
-
Inhibition by red wine extract, resveratrol, of cytokine release by alveolar macrophages in COPD
-
Culpitt, S.V. et al. (2003) Inhibition by red wine extract, resveratrol, of cytokine release by alveolar macrophages in COPD. Thorax 58, 942-946
-
(2003)
Thorax
, vol.58
, pp. 942-946
-
-
Culpitt, S.V.1
-
6
-
-
2942752051
-
Smoke induced changes in epithelial cell gene expression: Development of an in vitro model for COPD
-
Puljic, R. and Pahl, A. (2004) Smoke induced changes in epithelial cell gene expression: development of an in vitro model for COPD. ALTEX 21, 3-7
-
(2004)
ALTEX
, vol.21
, pp. 3-7
-
-
Puljic, R.1
Pahl, A.2
-
7
-
-
0033785188
-
Effect of cigarette smoke on the permeability and IL-1 beta and sICAM-1 release from cultured human bronchial epithelial cells of never-smokers, smokers, and patients with chronic obstructive pulmonary disease
-
Rusznak, C. et al. (2000) Effect of cigarette smoke on the permeability and IL-1 beta and sICAM-1 release from cultured human bronchial epithelial cells of never-smokers, smokers, and patients with chronic obstructive pulmonary disease. Am. J. Respir. Cell Mol. Biol. 23, 530-536
-
(2000)
Am. J. Respir. Cell Mol. Biol.
, vol.23
, pp. 530-536
-
-
Rusznak, C.1
-
8
-
-
0036070510
-
Glutathione prevents inhibition of fibroblast-mediated collagen gel contraction by cigarette smoke
-
Kim, H.J. et al. (2002) Glutathione prevents inhibition of fibroblast-mediated collagen gel contraction by cigarette smoke. Am. J. Physiol. Lung Cell Mol. Physiol. 283, L409-L417
-
(2002)
Am. J. Physiol. Lung Cell Mol. Physiol.
, vol.283
-
-
Kim, H.J.1
-
9
-
-
0002982441
-
Experimental emphysema: Its production with papain in normal and silicotic rats
-
Gross, P. et al. (1965) Experimental emphysema: its production with papain in normal and silicotic rats. Arch. Environ. Health 11, 50-58
-
(1965)
Arch. Environ. Health
, vol.11
, pp. 50-58
-
-
Gross, P.1
-
10
-
-
84907041622
-
The electrophoretic alpha-globulin pattern of serum in alpha-1-antitrypsin deficiency
-
Laurell, C.B. and Erikkson, S. (1963) The electrophoretic alpha-globulin pattern of serum in alpha-1-antitrypsin deficiency. Scand. J. Clin. Invest. 15, 132-140
-
(1963)
Scand. J. Clin. Invest.
, vol.15
, pp. 132-140
-
-
Laurell, C.B.1
Erikkson, S.2
-
11
-
-
0015903352
-
The induction of emphysema with elastase. I. The evolution of the lesion and the influence of serum
-
Kaplan, P.D. et al. (1973) The induction of emphysema with elastase. I. The evolution of the lesion and the influence of serum. J. Lab. Clin. Med. 82, 349-356
-
(1973)
J. Lab. Clin. Med.
, vol.82
, pp. 349-356
-
-
Kaplan, P.D.1
-
12
-
-
0036141863
-
Severity of elastase-induced emphysema is decreased in tumor necrosis factor-alpha and interleukin-1 beta receptor-deficient mice
-
Lucey, E.C. et al. (2002) Severity of elastase-induced emphysema is decreased in tumor necrosis factor-alpha and interleukin-1 beta receptor-deficient mice. Lab. Invest. 82, 79-85
-
(2002)
Lab. Invest.
, vol.82
, pp. 79-85
-
-
Lucey, E.C.1
-
13
-
-
15544388126
-
Oral N-acetylcysteine attenuates elastase-induced pulmonary emphysema in rats
-
Rubio, M.L. et al. (2004) Oral N-acetylcysteine attenuates elastase-induced pulmonary emphysema in rats. Chest 125, 1500-1506
-
(2004)
Chest
, vol.125
, pp. 1500-1506
-
-
Rubio, M.L.1
-
14
-
-
23644433723
-
Nrf2 is important for protection against elastase-induced pulmonary inflammation and subsequent emphysema
-
Ishii, Y. et al. (2004) Nrf2 is important for protection against elastase-induced pulmonary inflammation and subsequent emphysema. Am. J. Respir. Crit. Care Med. 169, A831
-
(2004)
Am. J. Respir. Crit. Care Med.
, vol.169
-
-
Ishii, Y.1
-
15
-
-
4344675775
-
Glucocorticoid resistant inflammation and enhanced emphysema in a rat elastase model
-
Birrell, M.A. et al. (2004) Glucocorticoid resistant inflammation and enhanced emphysema in a rat elastase model. Am. J. Respir. Crit. Care Med. 169, A68
-
(2004)
Am. J. Respir. Crit. Care Med.
, vol.169
-
-
Birrell, M.A.1
-
16
-
-
16944366965
-
Retinoic acid treatment abrogates elastase-induced pulmonary emphysema in rats
-
Massaro, G.D. and Massaro, D. (1997) Retinoic acid treatment abrogates elastase-induced pulmonary emphysema in rats. Nat. Med. 3, 675-677
-
(1997)
Nat. Med.
, vol.3
, pp. 675-677
-
-
Massaro, G.D.1
Massaro, D.2
-
17
-
-
0346094380
-
Bone marrow-derived cells contribute to lung regeneration after elastase-induced pulmonary emphysema
-
Ishizawa, K. et al. (2004) Bone marrow-derived cells contribute to lung regeneration after elastase-induced pulmonary emphysema. FEBS Lett. 556, 249-252
-
(2004)
FEBS Lett.
, vol.556
, pp. 249-252
-
-
Ishizawa, K.1
-
18
-
-
85030745462
-
Repair of pulmonary alveolus by bone marrow-derived stem cells for emphysema model in rabbits
-
Yuugetsu, H. et al. (2004) Repair of pulmonary alveolus by bone marrow-derived stem cells for emphysema model in rabbits. Am. J. Respir. Crit. Care Med. 169, A277
-
(2004)
Am. J. Respir. Crit. Care Med.
, vol.169
-
-
Yuugetsu, H.1
-
19
-
-
33645178218
-
Efficacy of the PDE 4 inhibitor, BAY 19-8004, in a smoke-induced model of pulmonary inflammation in the guinea pig
-
Fitzgerald, M.F. et al. (2001) Efficacy of the PDE 4 inhibitor, BAY 19-8004, in a smoke-induced model of pulmonary inflammation in the guinea pig. Am. J. Respir. Crit. Care Med. 163, A905
-
(2001)
Am. J. Respir. Crit. Care Med.
, vol.163
-
-
Fitzgerald, M.F.1
-
20
-
-
23644444834
-
Efficacy of the PDE4 inhibitor, BAY 19-8004 and a steroid in tobacco smoke-induced models of pulmonary inflammation in the mouse
-
Fitzgerald, M.F. et al. (2003) Efficacy of the PDE4 inhibitor, BAY 19-8004 and a steroid in tobacco smoke-induced models of pulmonary inflammation in the mouse. Am. J. Respir. Crit. Care Med. 167, A91
-
(2003)
Am. J. Respir. Crit. Care Med.
, vol.167
-
-
Fitzgerald, M.F.1
-
21
-
-
0034117111
-
Acute cigarette smoke-induced connective tissue breakdown is mediated by neutrophils and prevented by alpha 1-antitrypsin
-
Dhami, R. et al. (2000) Acute cigarette smoke-induced connective tissue breakdown is mediated by neutrophils and prevented by alpha 1-antitrypsin. Am. J. Respir. Cell Mol. Biol. 22, 244-252
-
(2000)
Am. J. Respir. Cell Mol. Biol.
, vol.22
, pp. 244-252
-
-
Dhami, R.1
-
22
-
-
0036727064
-
Acute cigarette smoke-induced connective tissue breakdown requires both neutrophils and macrophage metalloelastase in mice
-
Churg, A. et al. (2002) Acute cigarette smoke-induced connective tissue breakdown requires both neutrophils and macrophage metalloelastase in mice. Am. J. Respir. Cell Mol. Biol. 27, 368-374
-
(2002)
Am. J. Respir. Cell Mol. Biol.
, vol.27
, pp. 368-374
-
-
Churg, A.1
-
23
-
-
0037106511
-
Tumor necrosis factor-alpha is central to acute cigarette smoke-induced inflammation and connective tissue breakdown
-
Churg, A. et al. (2002) Tumor necrosis factor-alpha is central to acute cigarette smoke-induced inflammation and connective tissue breakdown. Am. J. Respir. Crit. Care Med. 166, 849-854
-
(2002)
Am. J. Respir. Crit. Care Med.
, vol.166
, pp. 849-854
-
-
Churg, A.1
-
24
-
-
0037447184
-
Macrophage metalloelastase mediates acute cigarette smoke-induced inflammation via tumor necrosis factor-alpha release
-
Churg, A. et al. (2003) Macrophage metalloelastase mediates acute cigarette smoke-induced inflammation via tumor necrosis factor-alpha release. Am. J. Respir. Crit. Care Med. 167, 1083-1089
-
(2003)
Am. J. Respir. Crit. Care Med.
, vol.167
, pp. 1083-1089
-
-
Churg, A.1
-
25
-
-
0141458218
-
Immunohistochemical evaluation of oxidative stress in murine lungs after cigarette smoke exposure
-
Aoshiba, K. et al. (2003) Immunohistochemical evaluation of oxidative stress in murine lungs after cigarette smoke exposure. Inhal. Toxicol. 15, 1029-1038
-
(2003)
Inhal. Toxicol.
, vol.15
, pp. 1029-1038
-
-
Aoshiba, K.1
-
26
-
-
23644436736
-
Efficacy of the PDE4 inhibitor, BAY 19-8004, in tobacco smoke models of COPD in the guinea pig
-
Fox, J.C. et al. (2003) Efficacy of the PDE4 inhibitor, BAY 19-8004, in tobacco smoke models of COPD in the guinea pig. Am. J. Respir. Crit. Care Med. 167, A91
-
(2003)
Am. J. Respir. Crit. Care Med.
, vol.167
-
-
Fox, J.C.1
-
27
-
-
11144311493
-
Cigarette smoke increases inflammation and lung virus titres caused by influenza infection in a mouse model of COPD exacerbation
-
Gualano, R.C. et al. (2004) Cigarette smoke increases inflammation and lung virus titres caused by influenza infection in a mouse model of COPD exacerbation. Am. J. Respir. Crit. Care Med. 169, A207
-
(2004)
Am. J. Respir. Crit. Care Med.
, vol.169
-
-
Gualano, R.C.1
-
28
-
-
85030745989
-
Development of an obstructive lung injury murine model induced by short-term cigarette smoke exposure
-
Fukuchi, K. et al. (2004) Development of an obstructive lung injury murine model induced by short-term cigarette smoke exposure. Am. J. Respir. Crit. Care Med. 169, A67
-
(2004)
Am. J. Respir. Crit. Care Med.
, vol.169
-
-
Fukuchi, K.1
-
29
-
-
0035446905
-
Effects of cigarette smoke in mice with different levels of alpha(1)-proteinase inhibitor and sensitivity to oxidants
-
Cavarra, E. et al. (2001) Effects of cigarette smoke in mice with different levels of alpha(1)-proteinase inhibitor and sensitivity to oxidants. Am. J. Respir. Crit. Care Med. 164, 886-890
-
(2001)
Am. J. Respir. Crit. Care Med.
, vol.164
, pp. 886-890
-
-
Cavarra, E.1
-
30
-
-
4243282859
-
Effect of acute and chronic exposures to cigarette smoke in two strains of mice: Efficacy of a matrix metalloproteinase (MMP) Inhibitor, BAY 15-7496, on emphysema development
-
Fitzgerald, M.F. et al. (2002) Effect of acute and chronic exposures to cigarette smoke in two strains of mice: Efficacy of a matrix metalloproteinase (MMP) Inhibitor, BAY 15-7496, on emphysema development. Am. J. Respir. Crit. Care Med. 165, A824
-
(2002)
Am. J. Respir. Crit. Care Med.
, vol.165
-
-
Fitzgerald, M.F.1
-
31
-
-
0030823772
-
Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice
-
Hautamaki, R.D. et al. (2002) Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science 277, 2002-2004
-
(2002)
Science
, vol.277
, pp. 2002-2004
-
-
Hautamaki, R.D.1
-
32
-
-
0036800045
-
Synthetic serine elastase inhibitor reduces cigarette smoke-induced emphysema in guinea pigs
-
Wright, J.L. et al. (2002) Synthetic serine elastase inhibitor reduces cigarette smoke-induced emphysema in guinea pigs. Am. J. Respir. Crit. Care Med. 166, 954-960
-
(2002)
Am. J. Respir. Crit. Care Med.
, vol.166
, pp. 954-960
-
-
Wright, J.L.1
-
33
-
-
0042031488
-
Alpha-1-antitrypsin ameliorates cigarette smoke-induced emphysema in the mouse
-
Churg, A. et al. (2003) Alpha-1-antitrypsin ameliorates cigarette smoke-induced emphysema in the mouse. Am. J. Respir. Crit. Care Med. 168, 199-207
-
(2003)
Am. J. Respir. Crit. Care Med.
, vol.168
, pp. 199-207
-
-
Churg, A.1
-
34
-
-
4444322565
-
Tumor necrosis factor-alpha drives 70% of cigarette smoke-induced emphysema in the mouse
-
June 7 (Epub ahead of print)
-
Churg, A. et al. (2004) Tumor necrosis factor-alpha drives 70% of cigarette smoke-induced emphysema in the mouse. Am. J. Respir. Crit. Care Med. June 7 (Epub ahead of print)
-
(2004)
Am. J. Respir. Crit. Care Med.
-
-
Churg, A.1
-
35
-
-
85030740635
-
Role of TNFa-R1 and TNFa-R2 in smoke-induced lung inflammation in mice
-
D'Hulst, A.I. and Pauwels, R.A. (2004) Role of TNFa-R1 and TNFa-R2 in smoke-induced lung inflammation in mice. Am. J. Respir. Crit. Care Med. 169, A830
-
(2004)
Am. J. Respir. Crit. Care Med.
, vol.169
-
-
D'Hulst, A.I.1
Pauwels, R.A.2
-
36
-
-
0036006795
-
Emphysematous lung destruction by cigarette smoke. The effects of latent adenoviral infection on the lung inflammatory response
-
Meshi, B. et al. (2002) Emphysematous lung destruction by cigarette smoke. The effects of latent adenoviral infection on the lung inflammatory response. Am. J. Respir. Cell Mol. Biol. 26, 52-57
-
(2002)
Am. J. Respir. Cell Mol. Biol.
, vol.26
, pp. 52-57
-
-
Meshi, B.1
-
37
-
-
9644273804
-
Impact of cigarette smoke on clearance and inflammation following Pseudomonas aeruginosa infection
-
August 18 (Epub ahead of print)
-
Drannik, A.G. et al. (2004) Impact of cigarette smoke on clearance and inflammation following Pseudomonas aeruginosa infection. Am. J. Respir. Crit. Care Med. August 18 (Epub ahead of print)
-
(2004)
Am. J. Respir. Crit. Care Med.
-
-
Drannik, A.G.1
-
38
-
-
0030781142
-
Regulated overexpression of interleukin 11 in the lung. Use to dissociate development-dependent and -independent phenotypes
-
Ray, P. et al. (1997) Regulated overexpression of interleukin 11 in the lung. Use to dissociate development-dependent and -independent phenotypes. J. Clin. Invest. 100, 2501-2511
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 2501-2511
-
-
Ray, P.1
-
39
-
-
0033660171
-
Inhibition of VEGF receptors causes lung cell apoptosis and emphysema
-
Kasahara, Y et al. (2000) Inhibition of VEGF receptors causes lung cell apoptosis and emphysema. J. Clin. Invest. 106, 1311-1319
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 1311-1319
-
-
Kasahara, Y.1
-
40
-
-
0038465920
-
Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade
-
Tuder, R.M. et al. (2003) Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade. Am. J. Respir. Cell Mol. Biol. 29, 88-97
-
(2003)
Am. J. Respir. Cell Mol. Biol.
, vol.29
, pp. 88-97
-
-
Tuder, R.M.1
-
41
-
-
84889615777
-
Ceramide upregulation is necessary for the development of rat emphysema induced by inhibition of the vascular endothelial growth factor receptors (VEGF-R)
-
Petrache, I. et al. (2004) Ceramide upregulation is necessary for the development of rat emphysema induced by inhibition of the vascular endothelial growth factor receptors (VEGF-R). Am. J. Respir. Crit. Care Med. 169, A206
-
(2004)
Am. J. Respir. Crit. Care Med.
, vol.169
-
-
Petrache, I.1
-
42
-
-
0038070219
-
Alveolar wall apoptosis causes lung destruction and emphysematous changes
-
Aoshiba, K. et al. (2003) Alveolar wall apoptosis causes lung destruction and emphysematous changes. Am. J. Respir. Cell Mol. Biol. 28, 555-562
-
(2003)
Am. J. Respir. Cell Mol. Biol.
, vol.28
, pp. 555-562
-
-
Aoshiba, K.1
-
43
-
-
0035077330
-
Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema
-
Kasahara, Y. et al. (2001) Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema. Am. J. Respir. Crit. Care Med. 163, 737-744
-
(2001)
Am. J. Respir. Crit. Care Med.
, vol.163
, pp. 737-744
-
-
Kasahara, Y.1
-
44
-
-
0034617999
-
New insights into the assembly of extracellular microfibrils from the analysis of the fibrillin 1 mutation in the tight skin mouse
-
Gayraud, B. et al. (2000) New insights into the assembly of extracellular microfibrils from the analysis of the fibrillin 1 mutation in the tight skin mouse. J. Cell Biol. 150, 667-680
-
(2000)
J. Cell Biol.
, vol.150
, pp. 667-680
-
-
Gayraud, B.1
-
45
-
-
0030052501
-
A scanning electron microscopic investigation of genetic emphysema in tight-skin, pallid, and beige mice, three different C57 BL/6J mutants
-
Keil, M. et al. (1996) A scanning electron microscopic investigation of genetic emphysema in tight-skin, pallid, and beige mice, three different C57 BL/6J mutants. Lab. Invest. 74, 353-362
-
(1996)
Lab. Invest.
, vol.74
, pp. 353-362
-
-
Keil, M.1
-
46
-
-
15844397403
-
Identification of the homologous beige and Chediak-Higashi syndrome genes
-
Barbosa, M.D. et al. (1996) Identification of the homologous beige and Chediak-Higashi syndrome genes. Nature 382, 262-265
-
(1996)
Nature
, vol.382
, pp. 262-265
-
-
Barbosa, M.D.1
-
47
-
-
0024374227
-
The beige mouse: Role of neutrophil elastase in the development of pulmonary emphysema
-
Starcher, B. and Williams, I. (1989) The beige mouse: role of neutrophil elastase in the development of pulmonary emphysema. Exp. Lung Res. 15, 785-800
-
(1989)
Exp. Lung Res.
, vol.15
, pp. 785-800
-
-
Starcher, B.1
Williams, I.2
-
48
-
-
0028246694
-
Mutations in the murine homologue of the Menkes gene in dappled and blotchy mice
-
Mercer, J.F. et al. (1994) Mutations in the murine homologue of the Menkes gene in dappled and blotchy mice. Nat. Genet. 6, 374-378
-
(1994)
Nat. Genet.
, vol.6
, pp. 374-378
-
-
Mercer, J.F.1
-
49
-
-
0017170881
-
Emphysema-like changes in the lungs of the blotchy mouse
-
Fisk, D.E. and Kuhn, C. (1976) Emphysema-like changes in the lungs of the blotchy mouse. Am. Rev. Respir. Dis. 113, 787-797
-
(1976)
Am. Rev. Respir. Dis.
, vol.113
, pp. 787-797
-
-
Fisk, D.E.1
Kuhn, C.2
-
50
-
-
0033836437
-
Mice bearing deletions of retinoic acid receptors demonstrate reduced lung elastin and alveolar numbers
-
McGowan, S. et al. (2000) Mice bearing deletions of retinoic acid receptors demonstrate reduced lung elastin and alveolar numbers. Am. J. Respir. Cell Mol. Biol. 23, 162-167
-
(2000)
Am. J. Respir. Cell Mol. Biol.
, vol.23
, pp. 162-167
-
-
McGowan, S.1
-
51
-
-
0030730837
-
Alveogenesis failure in PDGF-A-deficient mice is coupled to lack of distal spreading of alveolar smooth muscle cell progenitors during lung development
-
Lindahl, P. et al. (1997) Alveogenesis failure in PDGF-A-deficient mice is coupled to lack of distal spreading of alveolar smooth muscle cell progenitors during lung development. Development 124, 3943-3953
-
(1997)
Development
, vol.124
, pp. 3943-3953
-
-
Lindahl, P.1
-
52
-
-
0033056231
-
Emphysematous lesions, inflammation, and fibrosis in the lungs of transgenic mice overexpressing platelet-derived growth factor
-
Hoyle, G.W. et al. (1999) Emphysematous lesions, inflammation, and fibrosis in the lungs of transgenic mice overexpressing platelet-derived growth factor. Am. J. Pathol. 154, 1763-1775
-
(1999)
Am. J. Pathol.
, vol.154
, pp. 1763-1775
-
-
Hoyle, G.W.1
-
53
-
-
0031700905
-
FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung
-
Weinstein, M. et al. (1998) FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung. Development 125, 3615-3623
-
(1998)
Development
, vol.125
, pp. 3615-3623
-
-
Weinstein, M.1
-
54
-
-
0037050030
-
Fibulin-5/DANCE is essential for elastogenesis in vivo
-
Nakamura, T. et al. (2002) Fibulin-5/DANCE is essential for elastogenesis in vivo. Nature 415, 171-175
-
(2002)
Nature
, vol.415
, pp. 171-175
-
-
Nakamura, T.1
-
55
-
-
0033823643
-
Impaired distal airway development in mice lacking elastin
-
Wendel, D.P. et al. (2000) Impaired distal airway development in mice lacking elastin. Am. J. Respir. Cell Mol. Biol. 23, 320-326
-
(2000)
Am. J. Respir. Cell Mol. Biol.
, vol.23
, pp. 320-326
-
-
Wendel, D.P.1
-
56
-
-
0035879135
-
Defects in pulmonary vasculature and perinatal lung hemorrhage in mice heterozygous null for the forkhead box f1 transcription factor
-
Kalinichenko, V.V. et al. (2001) Defects in pulmonary vasculature and perinatal lung hemorrhage in mice heterozygous null for the forkhead box f1 transcription factor. Dev. Biol. 235, 489-506
-
(2001)
Dev. Biol.
, vol.235
, pp. 489-506
-
-
Kalinichenko, V.V.1
-
57
-
-
0035313164
-
Pulmonary hypoplasia in mice lacking tumor necrosis factor-alpha converting enzyme indicates an indispensable role for cell surface protein shedding during embryonic lung branching morphogenesis
-
Zhao, J. et al. (2001) Pulmonary hypoplasia in mice lacking tumor necrosis factor-alpha converting enzyme indicates an indispensable role for cell surface protein shedding during embryonic lung branching morphogenesis. Dev. Biol. 232, 204-218
-
(2001)
Dev. Biol.
, vol.232
, pp. 204-218
-
-
Zhao, J.1
-
58
-
-
0033393087
-
The basic-helix-loop-helix protein pod1 is critically important for kidney and lung organogenesis
-
Quaggin, S.E. et al. (1999) The basic-helix-loop-helix protein pod1 is critically important for kidney and lung organogenesis. Development 126, 5771-5783
-
(1999)
Development
, vol.126
, pp. 5771-5783
-
-
Quaggin, S.E.1
-
59
-
-
0034679559
-
Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction
-
Blackburn, M.R. et al. (2000) Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction. J. Exp. Med. 192, 159-170
-
(2000)
J. Exp. Med.
, vol.192
, pp. 159-170
-
-
Blackburn, M.R.1
-
60
-
-
0344064891
-
Inhibition of alveolarization and altered pulmonary mechanics in mice expressing GATA-6
-
Liu, C. et al. (2003) Inhibition of alveolarization and altered pulmonary mechanics in mice expressing GATA-6. Am. J. Physiol. Lung Cell Mol. Physiol. 285, 1246-1254
-
(2003)
Am. J. Physiol. Lung Cell Mol. Physiol.
, vol.285
, pp. 1246-1254
-
-
Liu, C.1
-
61
-
-
33645186478
-
Epithelial cell PPAR gamma is necessary for lung maturation
-
Mariani, T.J. et al. (2004) Epithelial cell PPAR gamma is necessary for lung maturation. Am. J. Respir. Crit. Care Med. 169, 790
-
(2004)
Am. J. Respir. Crit. Care Med.
, vol.169
, pp. 790
-
-
Mariani, T.J.1
-
62
-
-
33645186806
-
Impaired lung alveolization in PECAM-1-null mice
-
Cao, G. et al. (2004) Impaired lung alveolization in PECAM-1-null mice. Am. J. Respir. Crit. Care Med. 169, 790
-
(2004)
Am. J. Respir. Crit. Care Med.
, vol.169
, pp. 790
-
-
Cao, G.1
-
63
-
-
0037373277
-
Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome
-
Neptune, E.R. et al. (2003) Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome. Nat. Genet. 33, 407-411
-
(2003)
Nat. Genet.
, vol.33
, pp. 407-411
-
-
Neptune, E.R.1
-
64
-
-
0032743997
-
The pallid gene encodes a novel, syntaxin 13-interacting protein involved in platelet storage pool deficiency
-
Huang, L. et al. (1999) The pallid gene encodes a novel, syntaxin 13-interacting protein involved in platelet storage pool deficiency. Nat. Genet. 23, 329-332
-
(1999)
Nat. Genet.
, vol.23
, pp. 329-332
-
-
Huang, L.1
-
65
-
-
0035525745
-
Alveolar macrophage deficiency in osteopetrotic mice deficient in macrophage colony-stimulating factor is spontaneously corrected with age and associated with matrix metalloproteinase expression and emphysema
-
Shibata, Y. et al. (2001) Alveolar macrophage deficiency in osteopetrotic mice deficient in macrophage colony-stimulating factor is spontaneously corrected with age and associated with matrix metalloproteinase expression and emphysema. Blood 98, 2845-2852
-
(2001)
Blood
, vol.98
, pp. 2845-2852
-
-
Shibata, Y.1
-
66
-
-
0034833362
-
Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3)
-
Leco, K.J. et al. (2001) Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3). J. Clin. Invest. 108, 817-829
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 817-829
-
-
Leco, K.J.1
-
67
-
-
0034705208
-
Increased metalloproteinase activity, oxidant production, and emphysema in surfactant protein D gene-inactivated mice
-
Wert, S.E. et al. (2000) Increased metalloproteinase activity, oxidant production, and emphysema in surfactant protein D gene-inactivated mice. Proc. Natl. Acad. Sci. USA 97, 5972-5977
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5972-5977
-
-
Wert, S.E.1
-
68
-
-
1642379630
-
Lysosomal acid lipase deficiency causes respiratory inflammation and destruction in the lung
-
Lian, X. et al. (2003) Lysosomal acid lipase deficiency causes respiratory inflammation and destruction in the lung. Am. J. Physiol. Lung Cell Mol. Physiol. 286, L801-L807
-
(2003)
Am. J. Physiol. Lung Cell Mol. Physiol.
, vol.286
-
-
Lian, X.1
-
69
-
-
0030724491
-
Mutation of the mouse klotho gene leads to a syndrome resembling ageing
-
Kuro-o, M. et al. (1997) Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature 390, 45-51
-
(1997)
Nature
, vol.390
, pp. 45-51
-
-
Kuro-O, M.1
-
70
-
-
0037435009
-
Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp 12-dependent emphysema
-
Morris, D.G. et al. (2003) Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp 12-dependent emphysema. Nature 422, 169-173
-
(2003)
Nature
, vol.422
, pp. 169-173
-
-
Morris, D.G.1
-
71
-
-
0037216547
-
Emphysematous changes are caused by degradation of type III collagen in transgenic mice expressing MMP-1
-
Shiomi, T. et al. (2003) Emphysematous changes are caused by degradation of type III collagen in transgenic mice expressing MMP-1. Exp. Lung Res. 29, 1-15
-
(2003)
Exp. Lung Res.
, vol.29
, pp. 1-15
-
-
Shiomi, T.1
-
72
-
-
10744226927
-
Overexpression of placenta growth factor contributes to the pathogenesis of pulmonary emphysema
-
Tsao, P.N. et al. (2004) Overexpression of placenta growth factor contributes to the pathogenesis of pulmonary emphysema. Am. J. Respir. Crit. Care Med. 169, 505-511
-
(2004)
Am. J. Respir. Crit. Care Med.
, vol.169
, pp. 505-511
-
-
Tsao, P.N.1
-
73
-
-
0033761127
-
Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema
-
Zheng, T et al. (2000) Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema. J. Clin. Invest. 106, 1081-1093
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 1081-1093
-
-
Zheng, T.1
-
74
-
-
0034606218
-
Interferon gamma induction of pulmonary emphysema in the adult murine lung
-
Wang, Z. et al. (2000) Interferon gamma induction of pulmonary emphysema in the adult murine lung. J. Exp. Med. 192, 1587-1600
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1587-1600
-
-
Wang, Z.1
-
75
-
-
1842504010
-
Lymphoid tissue and emphysema in the lungs of transgenic mice inducibly expressing tumor necrosis factor-alpha
-
Vuillemenot, B.R. et al. (2004) Lymphoid tissue and emphysema in the lungs of transgenic mice inducibly expressing tumor necrosis factor-alpha. Am. J. Respir. Cell Mol. Biol. 30, 438-448
-
(2004)
Am. J. Respir. Cell Mol. Biol.
, vol.30
, pp. 438-448
-
-
Vuillemenot, B.R.1
|