Mediastinal germ cell tumor associated with histiocytic sarcoma of spleen: Case report of an unusual association

International Journal of Surgical Pathology

Volumn 13, Issue 3, 2005, Pages 299-303

  Song, Sang Yong ^a,b   Ko, Young Hyeh ^a   Ahn, Geunghwan ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Samsung Medical Center   (South Korea)

Author keywords

Angiosarcoma; Germ cell tumor; Malignant lymphoma; Mediastinum; Spleen

Indexed keywords

CD31 ANTIGEN; CD4 ANTIGEN; CD68 ANTIGEN;

ADOLESCENT; ANGIOSARCOMA; ARTICLE; CARCINOGENESIS; CASE REPORT; CELL NUCLEUS MEMBRANE; CHROMOSOME 5; CLINICAL FEATURE; CYTOGENETICS; CYTOPLASM; DISEASE COURSE; ECHOGRAPHY; EMBRYONAL CARCINOMA; GERM CELL TUMOR; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; LEUKEMIA; MALE; MEDIASTINUM TUMOR; PRIORITY JOURNAL; SARCOMA; SEMINOMA; SPLEEN CANCER; SPLENOMEGALY; TERATOMA; TRISOMY 8; YOLK SAC TUMOR;

ADOLESCENT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BLEOMYCIN; CHEMOTHERAPY, ADJUVANT; CISPLATIN; ETOPOSIDE; HEMANGIOSARCOMA; HISTIOCYTOSIS, MALIGNANT; HUMANS; MALE; MEDIASTINAL NEOPLASMS; NEOPLASMS, MULTIPLE PRIMARY; SEMINOMA; SPLENIC NEOPLASMS; SPLENOMEGALY; TREATMENT OUTCOME;

EID: 23644442562     PISSN: 10668969     EISSN: None     Source Type: Journal    
DOI: 10.1177/106689690501300314     Document Type: Article

References (15)

1. Nichols CR, Hoffman R, Einhorn LH, Williams SD, Wheeler LA, Garnick MB. Hematologic malignancies associated with primary mediastinal germ-cell tumors. Ann Intern Med 102:603-609, 1985
2. DeMent SH, Eggleston JC, Spivak JL. Association between mediastinal germ cell tumors and hematologic malignancies. Report of two cases and review of the literature. Am J Surg Pathol 9:23-30, 1985
3. Saito A, Watanabe K, Kusakabe T, Abe M, Suzuki T. Mediastinal mature teratoma with coexistence of angiosarcoma, granulocytic sarcoma and a hematopoietic region in the tumor: A rare case of association between hematological malignancy and mediastinal germ cell tumor. Pathol Int 48:749-753, 1998
4. Nichols CR, Roth BJ, Heerema N, Griep J, Tricot G. Hematologic neoplasia associated with primary mediastinal germ-cell tumors. N Engl J Med 322:1425-1429, 1990
5. Hartmann JT, Nichols CR, Droz JP, Horwich A, Gerl A, Fossa SD, Beyer J, Pont J, Fizazi K, Einhorn L, Kanz L, Bokemeyer C. Hematologic disorders associated with primary mediastinal nonseminomatous germ cell tumors. J Natl Cancer Inst 92:54-61, 2000
6. Ladanyi M, Samaniego F, Reuter VE, Motzer RJ, Jhanwar SC, Bosl GJ, Chaganti RS. Cytogenetic and immunohistochemical evidence for the germ cell origin of a subset of acute leukemias associated with mediastinal germ cell tumors. J Natl Cancer Inst 82:221-227, 1990
7. Orazi A, Neiman RS, Ulbright TM, Heerema NA, John K, Nichols CR. Hematopoietic precursor cells within the yolk sac tumor component are the source of secondary hematopoietic malignancies in patients with mediastinal germ cell tumors. Cancer 71:3873-3881, 1993
8. Third MIC Cooperative Study Group. Recommendations for a morphologic, immunologic, and cytogenetic (MIC) working classification of the primary and therapy-related myelodysplastic disorders. Cancer Genet Cytogenet 32:1-10, 1988
9. Weiss LM, Grogan TM, Muller-Hermelink HK, Stein H, Dura T, Favara B, Paulli M, Feller AC (eds). Histiocytic sarcoma. In Jaffe ES, Harris NL, Stein H, Vardiman JW (eds): Pathology and genetics of tumours of haematopoietic and lymphoid tissues. IARC Press, Lyon, pp. 278-279, 2001
10. Pileri SA, Grogan TM, Harris NL, Banks P, Campo E, Chan JK, Favera RD, Delsol G, De Wolf-Peeters C, Falini B, Gascoyne RD, Gaulard P, Gatter KC, Isaacson PG, Jaffe ES, Kluin P, Knowles DM, Mason DY, Mori S, Muller-Hermelink HK, Piris MA, Ralfkiaer E, Stein H, Su IJ, Warnke RA, Weiss LM. Tumours of histiocytes and accessory dendritic cells: An immunohistochemical approach to classification from the International Lymphoma Study Group based on 61 cases. Histopathology 41:1-29, 2002
11. Copie-Bergman C, Wotherspoon AC, Norton AJ, Diss TC, Isaacson PG. True histiocytic lymphoma: A morphologic, immunohistochemical, and molecular genetic study of 13 cases. Am J Surg Pathol 22:1386-1392, 1998
12. Hornick JL, Jaffe ES, Fletcher CD. Extranodal histiocytic sarcoma: Clinicopathologic analysis of 14 cases of a rare epithelioid malignancy. Am J Surg Pathol 28:1133-1144, 2004
13. Audouin J, Vercelli-Retta J, Le Tourneau A, Adida C, Camilleri-Broet S, Molina T, Diebold J. Primary histiocytic sarcoma of the spleen associated with erythrophagocytic histiocytosis. Pathol Res Pract 199:107-112, 2003
14. Kimura H, Nasu K, Sakai C, Shiga Y, Miyamoto E, Shintaku M, Wakatsuki S, Tominaga K, Abe M, Maruyama Y. Histiocytic sarcoma of the spleen associated with hypoalbuminemia, hypogamma-globulinemia and thrombocytopenia as a possibly unique clinical entity-report of three cases. Leuk Lymphoma 31:217-224, 1998
15. Franchino C, Reich C, Distenfeld A, Ubriaco A, Knowles DM. A clinicopathologically distinctive primary splenic histiocytic neoplasm. Demonstration of its histiocyte derivation by immunophenotypic and molecular genetic analysis. Am J Surg Pathol 12:398-404, 1988