Expression and regulation characteristics of the substance P receptor in human skin keratinocytes and fibroblasts

Chinese Pharmacological Bulletin

Volumn 21, Issue 6, 2005, Pages 667-670

  Liu, Ji Yong ^a   Hu, Jin Hong ^a   Zhu, Quan Gang ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Fibroblast; HaCat cell line; Human keratinocytes; Skin inflammation; Substance P receptor

Indexed keywords

CETIRIZINE; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; MESSENGER RNA; NEUROKININ 1 RECEPTOR; SPANTIDE; SUBSTANCE P RECEPTOR;

ARTICLE; CELL CULTURE; CELL MEMBRANE; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; FIBROBLAST; FLOW CYTOMETRY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; KERATINOCYTE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 23444458587     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Welss T, Basketter DA, Schroder KR. In vitro skin irritation: facts and future. State of the art review of mechanisms and models[J]. Toxicol In Vitro, 2004,18(3):231-43.
2. Luger TA. Neuromediators-a crucial component of the skin immune system[J]. J Dermatol Sci, 2002,30(2):87-93
3. O'Sullivan RL, Lipper G, Lerner EA. The neuro-immuno-cutaneous-endocrine network: Relationship of mind and skin[J]. Arch Dermatol, 1998,134(11):1431-5.
4. Reibiger I, Aust G, Tscheudschilsuren G et al. The expression of substance P and its neurokinin-1 receptor mRNA in the bovine corpus luteum of early developmental stage[J]. Neurosci Lett, 2001, 299(1):49-52.
5. Lai JP, Zhang GX, Campbell DE et al. Detection of substance P and its receptor in human fetal microglia[J]. Neuroscience, 2000, 101(6):1137-44.
6. Kim KH, Park KC, Chung JH, Choi HR. The effect of substance P on peripheral blood mononuclear cells in patients with atopic dermatitis[J]. J Dermatol Sci, 2003,32(2):115-24.
7. Seiffert K, Granstein RD. Neuropeptides and neuroendocrine hormones in ultraviolet radiation-induced immunosuppression[J]. Methods, 2002,28(1):97-103.
8. Park YM, Kim CW. The effects of substance P and vasoactive intestinal peptide on interleukin-6 synthesis in cultured human keratinocytes[J]. J Dermatol Sci, 1999,22(1):17-23.
9. Zwirner NW, Dole K, Stastny P. Differential surface expression of MICA by endothelial cells, fibroblasts, keratinocytes, and monocytes[J]. Hum Immunol, 1999,60(4):323-30.
10. Borici-Mazi R, Kouridakis S, Kontou-Fili K. Cutaneous responses to substance P and calcitonin gene-related peptide in chronic urticaria; the effect of cetirizine and dimethindene[J]. Allergy, 1999, 54(1):46-56.