Porphyria cutanea tarda in a Swedish population: Risk factors and complications

Acta Dermato-Venereologica

Volumn 85, Issue 4, 2005, Pages 337-341

  Rossmann Ringdahl, Ingrid ^a   Olsson, Rolf ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Diabetes mellitus; Haemochromatosis; Hepatitis; Life expectancy; Porphyria cutanea tarda

Indexed keywords

ESTROGEN; FERRITIN; PORPHYRIN; TRANSFERRIN; VIRUS ANTIBODY;

ADULT; AGED; ALCOHOL ABUSE; DIABETES MELLITUS; FEMALE; GENE MUTATION; HEMOCHROMATOSIS; HEPATITIS; HEPATITIS C VIRUS; HIGH RISK POPULATION; HUMAN; IMPAIRED GLUCOSE TOLERANCE; LIFE EXPECTANCY; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; ORAL GLUCOSE TOLERANCE TEST; PORPHYRIA CUTANEA TARDA; PREVALENCE; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SWEDEN;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHILD; FEMALE; FERRITINS; GENETIC PREDISPOSITION TO DISEASE; HEMOCHROMATOSIS; HUMANS; LIVER FUNCTION TESTS; MALE; MIDDLE AGED; PORPHYRIA CUTANEA TARDA; PORPHYRINS; PREVALENCE; RETROSPECTIVE STUDIES; RISK FACTORS; SWEDEN;

EID: 23444455257     PISSN: 00015555     EISSN: None     Source Type: Journal    
DOI: 10.1080/00015550510033688     Document Type: Review

References (37)

1. Kushner JP, Barbuto AJ, Lee GR. An inherited enzymatic defect in porphyria cutanea tarda: decreased uroporphyrinogen decarboxylase activity. J Clin Invest 1976; 58: 1089-1097.
2. Christiansen L, Bygum A, Jensen A, Brandrup F, Thomsen K, Horder M, et al. Uroporphyrinogen decarboxylase gene mutations in Danish patients with porphyria cutanea tarda. Scand J Clin Lab Invest 2000; 60: 611-615.
3. Elder GH. Porphyria cutanea tarda. Semin Liver Dis 1998; 18: 67-75.
4. Thunell S, Harper P. Porphyrins, porphyrin metabolism, porphyrias. III. Diagnosis, care and monitoring in porphyria cutanea tarda - suggestions for a handling programme. Scand J Clin Lab Invest 2000; 60: 561-579.
5. Bulaj ZJ, Phillips JD, Ajioka RS, Franklin MR, Griffen LM, Guinee DJ, et al. Hemochromatosis genes and other factors contributing to the pathogenesis of porphyria cutanea tarda. Blood 2000; 95: 1565-1571.
6. Herrero C, Vicente A, Bruguera M, Ercilla MG, Barrera JM, Vidal J, et al. Is hepatitis C virus infection a trigger of porphyria cutanea tarda? Lancet 1993; 341: 788-789.
7. Fargion S, Piperno A, Cappellini MD, Sampietro M, Fracanzani AL, Romano R, et al. Hepatitis C virus and porphyria cutanea tarda: evidence of a strong association. Hepatology 1992; 16: 1322-1326.
8. Tsukazaki N, Watanabe M, Irifune H. Porphyria cutanea tarda and hepatitis C virus infection. Br J Dermatol 1998; 138: 1015-1017.
9. Bonkovsky HL, Poh-Fitzpatrick M, Pimstone N, Obando J, Di Bisceglie A, Tattrie C, et al. Porphyria cutanea tarda, hepatitis C, and HFE gene mutations in North America. Hepatology 1998; 27: 1661-1669.
10. Lamoril J, Andant C, Bogard C, Puy H, Gouya L, Pawlotsky JM, et al. Epidemiology of hepatitis C and G in sporadic and familial porphyria cutanea tarda. Hepatology 1998; 27: 848-852.
11. Stolzel U, Kostler E, Koszka C, Stoffler-Meilicke M, Schuppan D, Somasundaram R, et al. Low prevalence of hepatitis C virus infection in porphyria cutanea tarda in Germany. Hepatology 1995; 21: 1500-1503.
12. Malina L, Stransky J, Zdarsky E. Geographical differences in prevalence of hepatitis C virus infection in PCT (porphyria cutanea tarda). Br J Dermatol 1997; 136: 291-292.
13. Salmon P, Oakley A, Rademaker M, Duffill M. Hepatitis C virus infection and porphyria cutanea tarda in Australasia. Arch Dermatol 1996; 132: 91.
14. Linet MS, Gridley G, Nyren O, Mellemkjaer L, Olsen JH, Keehn S, et al. Primary liver cancer, other malignancies, and mortality risks following porphyria: a cohort study in Denmark and Sweden. Am J Epidemiol 1999; 149: 1010-1015.
15. Siersema PD, ten Kate FJ, Mulder PG, Wilson JH. Hepatocellular carcinoma in porphyria cutanea tarda: frequency and factors related to its occurrence. Liver 1992; 12: 56-61.
16. Fracanzani AL, Taioli E, Sampietro M, Fatta E, Bertelli C, Fiorelli G, et al. Liver cancer risk is increased in patients with porphyria cutanea tarda in comparison to matched control patients with chronic liver disease. J Hepatol 2001; 35: 498-503.
17. Cram DL, Epstein JH, Tuffanelli DL. Lupus erythematosus and porphyria. Coexistence in seven patients. Arch Dermatol 1973; 108: 779-784.
18. Clemmensen O, Thomsen K. Porphyria cutanea tarda and systemic lupus erythematosus. Arch Dermatol 1982; 118: 160-162.
19. Griso D, Macri A, Biolcati G, Topi G. Does an association exist between PCT and SLE? Results of a study on autoantibodies in 159 patients affected with PCT. Arch Dermatol Res 1989; 281: 291-292.
20. Adams P, Brissot P, Powell LW. EASL International Consensus Conference on Haemochromatosis. J Hepatol 2000; 33: 485-504.
21. Santos JL, Grandal M, Fontanellas A, Moran MJ, Enriquez de Salamanca R. [Prevalence of porphyria cutanea tarda in Madrid and relationship between urine porphyrin and ethanol intake in a multiple linear regression model.] Med Clin (Barc) 1996; 107: 614-616 [in Spanish].
22. Bygum A, Christiansen L, Petersen NE, Horder M, Thomsen K, Brandrup F. Familial and sporadic porphyria cutanea tarda: clinical, biochemical and genetic features with emphasis on iron status. Acta Derm Venereol 2003; 83: 115-120.
23. Held JL, Sassa S, Kappas A, Harber LC. Erythrocyte uroporphyrinogen decarboxylase activity in porphyria cutanea tarda: a study of 40 consecutive patients. J Invest Dermatol 1989; 93: 332-334.
24. Gisbert JP, Garcia-Buey L, Pajares JM, Moreno-Otero R. Prevalence of hepatitis C virus infection in porphyria cutanea tarda: systematic review and meta-analysis. J Hepatol 2003; 39: 620-627.
25. Hoffmann G, Berglund G, Elmstahl S, Eriksson S, Verbaan H, Widell A, et al. Prevalence and clinical spectrum of chronic viral hepatitis in a middle-aged Swedish general urban population. Scand J Gastroenterol 2000; 35: 861-865.
26. Bellentani S, Miglioli L, Masutti F, Saccoccio G, Tiribelli C. Epidemiology of hepatitis C virus infection in Italy: the slowly unraveling mystery. Microbes Infect 2000; 2: 1757-1763.
27. Tannapfel A, Stolzel U, Kostler E, Melz S, Richter M, Keim V, et al. C282Y and H63D mutation of the hemochromatosis gene in German porphyria cutanea tarda patients. Virchows Arch 2001; 439: 1-5.
28. Beckman LE, Sjoberg K, Eriksson S, Beckman L. Haemochromatosis gene mutations in Finns, Swedes and Swedish Saamis. Hum Hered 2001; 52: 110-112.
29. Phatak PD, Ryan DH, Cappuccio J, Oakes D, Braggins C, Provenzano K, et al. Prevalence and penetrance of HFE mutations in 4865 unselected primary care patients. Blood Cells Mol Dis 2002; 29: 41-47.
30. Cullen LM, Summerville L, Glassick TV, Crawford DH, Powell LW, Jazwinska EC. Neonatal screening for the hemochromatosis defect. Blood 1997; 90: 4236-4237.
31. Furuyama K, Kondo M, Hirata K, Fujita H, Sassa S. Extremely rare association of HFE mutations with porphyria cutanea tarda in Japanese patients. Hepatology 1999; 30: 1532-1533.
32. Roberts AG, Whatley SD, Morgan RR, Worwood M, Elder GH. Increased frequency of the haemochromatosis Cys282Tyr mutation in sporadic porphyria cutanea tarda. Lancet 1997; 349: 321-323.
33. Sampietro M, Piperno A, Lupica L, Arosio C, Vergani A, Corbetta N, et al. High prevalence of the His63Asp HFE mutation in Italian patients with porphyria cutanea tarda. Hepatology 1998; 27: 181-184.
34. Kostler E. [Porphyria cutanea tarda and diabetes mellitus.] Dermatol Monatsschr 1986; 172: 481-484 [in German].
35. Grossman ME, Bickers DR, Poh-Fitzpatrick MB, Deleo VA, Harber LC. Porphyria cutanea tarda. Clinical features and laboratory findings in 40 patients. Am J Med 1979; 67: 277-286.
36. Harmsen P, Berglund G, Larsson O, Tibblin G, Wilhelmsen L. Stroke registration in Goteborg, Sweden, 1970-75. Incidence and fatality rates. Acta Med Scand 1979; 206: 337-344.
37. Njajou OT, Hollander M, Koudstaal PJ, Hofman A, Witteman JC, Breteler MM, et al. Mutations in the hemochromatosis gene (HFE) and stroke. Stroke 2002; 33: 2363-2366.