A multi-center randomized trial of buprenorphine-naloxone versus clonidine for opioid detoxification: Findings from the National Institute on Drug Abuse Clinical Trials Network

Addiction

Volumn 100, Issue 8, 2005, Pages 1090-1100

  Ling, Walter ^a,l   Amass, Leslie ^b   Shoptaw, Steve ^a   Annon, Jeffrey J ^a   Hillhouse, Maureen ^a   Babcock, Dean ^c   Brigham, Greg ^d   Harrer, Judy ^e   Reid, Malcolm ^f   Muir, Joan ^g   Buchan, Betty ^h   Orr, Debbie ⁱ   Woody, George ^j   Krejci, Jonathan ^k   Ziedonis, Douglas ^l  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b FRIENDS RESEARCH INSTITUTE   (United States)

^c Midtown Mental Health Center   (United States)

^d Maryhaven   (United States)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

^f NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF MIAMI   (United States)

^h Center for Drug Free Living ^*

ⁱ UNIVERSITY OF PENNSYLVANIA   (United States)

^j Mercer Trenton Addiction Science Center   (United States)

^k RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^l UNIVERSITY OF CALIFORNIA   (United States)

more..

Author keywords

Buprenorphine; Clonidine; Detoxification; Opiate dependence; Treatment

Indexed keywords

ATROPINE; BUP NX; BUPRENORPHINE; BUPRENORPHINE PLUS NALOXONE; CLONIDINE; DIPHENHYDRAMINE; DOXEPIN; HYDROXYZINE; IBUPROFEN; LOPERAMIDE; LORAZEPAM; METHOCARBAMOL; NALOXONE; OPIATE; OXAZEPAM; PARACETAMOL; PHENOBARBITAL; SCOPOLAMINE BROMIDE; TRAZODONE; TRIMETHOBENZAMIDE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL ENDOCARDITIS; BLISTER PACK; CELLULITIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; DRUG ABUSE; DRUG DEPENDENCE TREATMENT; DRUG DETOXIFICATION; DRUG EFFICACY; DRUG PACKAGING; DRUG URINE LEVEL; DRUG WITHDRAWAL; HOSPITAL PATIENT; HUMAN; MAJOR CLINICAL STUDY; MULTICENTER STUDY; NAUSEA; NEPHROLITHIASIS; OPIATE ADDICTION; OUTPATIENT; PATIENT COUNSELING; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY FAILURE; SELF HELP; SIDE EFFECT; SUICIDAL BEHAVIOR; TREATMENT OUTCOME; VOMITING;

ADULT; BUPRENORPHINE; CLONIDINE; FEMALE; HUMANS; MALE; METABOLIC DETOXICATION, DRUG; NALOXONE; NARCOTIC ANTAGONISTS; OPIOID-RELATED DISORDERS;

EID: 23444446372     PISSN: 09652140     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1360-0443.2005.01154.x     Document Type: Article

References (27)

1. Amass, L., Bickel, W. K., Higgins, S. T. & Hughes, J. R. (1994) A preliminary investigation of outcome following gradual or rapid buprenorphine detoxification. Journal of Addictive Diseases, 13, 33-45.
2. Amass, L., Kamien, J. B. & Mikulich, S. K. (2000) Efficacy of daily and alternate-day dosing regimens with the combination buprenorphine-naloxone tablet. Drug and Alcohol Dependence, 58, 143-152.
3. Amass, L., Ling, W., Freese, T. E., Reiber, C., Annon, J. J., Cohen, A. J. et al. (2004) Bringing buprenorphine-naloxone detoxification to community treatment providers: the NIDA Clinical Trials Network field Experience. American Journal on Addictions, 13, S42-S66.
4. American Psychiatric Association (1994) Diagnostic and Statistical Manual of Mental Disorders, 4th edn. Washington, DC: Author.
5. Becker, A. B., Strain, E. C., Bigelow, G. E., Stitzer, M. L. & Johnson, R. E. (2001) Gradual dose taper following chronic buprenorphine. American Journal on Addictions, 10, 111-121.
6. Bickel, W. K. & Amass, L. (1995) Buprenorphine treatment of opiate dependence: a review. Experimental and Clinical Psychopharmology, 3, 477-489.
7. Bickel, W. K., Amass, L., Higgins, S. T., Badger, G. J. & Esch, R. A. (1997) Effects of adding behavioral treatment to opiate detoxification with buprenorphine. Journal of Consulting and Clinical Psychology, 65, 803-810.
8. Bickel, W. K., Stitzer, M. I., Bigelow, G. E., Liebson, I. A., Jasinski, D. R. & Johnson, R. E. (1988a) A clinical trial of buprenorphine: comparison with methadone in the detoxification of heroin addicts. Clinical Pharmacology and Therapeutics, 43, 72-78.
9. Bickel, W. K., Stitzer, M. I., Bigelow, G. E., Liebson, I. A., Jasinski, D. R. & Johnson, R. E. (1988b) Buprenorphine: dose-related blockade of opioid challenge effects in opioid dependent humans. Journal of Pharmacology and Experimental Therapeutics, 247, 47-53.
10. Boatwright, D. E. (2002) Buprenorphine and addiction: challenges for the pharmacist. Journal of American Pharmacological Association, 42, 432-438.
11. Cheskin, L. J., Fudala, P. J. & Johnson, R. E. (1994) A controlled comparison of buprenorphine and clonidine for acute detoxification from opioids. Drug and Alcohol Dependence, 36, 115-121.
12. Childress, A. R., McLellan, A. T. & O'Brien, C. P. (1986) Conditioned responses in a methadone population: a comparison of laboratory, clinic, and nature settings. Journal of Substance Abuse Treatment, 3, 173-179.
13. Cohen, J. (1988) Statistical power analysis for the behavioral sciences. Hillsdale, NJ: Lawrence Erlbaum.
14. Elashoff, J. (2002) nQuery Advisor (Version 5.0) [Computer software]. Los Angeles, CA.
15. Fingerhood, M. I., Thompson, M. R. & Jasinski, D. R. (2001) A comparison of clonidine and buprenorphine in the outpatient treatment of opiate withdrawal. Substance Abuse, 22, 193-199.
16. Gowing, L., Farrell, M., Ali, R. & White, J. (2003) Alpha 2 adrenergic agonists for the management of opioid withdrawal. Cochrane Database Systemic Review, CD 002024.
17. Hser, Y. I., Hoffman, V., Grella, C. E. & Anglin, M. D. (2001) A 33-year follow-up of narcotic addicts. Archives of General Psychiatry, 58, 503-508.
18. Johnson, R. E., Strain, E. & Amass, L. (2003) Buprenorphine: how to use it right. Drug and Alcohol Dependence, 70, S59-S77.
19. Kaplan, R. F., Cooney, N. L., Baker, L. H., Gillespie, R. A., Meyer, R. E. & Pomerlau, O. F. (1985) Reactivity to alcohol-related cues: Physiological and subjective responses in alcoholics and non-problem drinkers. Journal of Studies on Alcohol, 46, 267-272.
20. Lamb, S., Greenlick, M. R. & McCarty, D. (1998) Bridging the Gap Between Practice and Research: Forging Partnerships with Community-Based Drug and Alcohol Treatment. Washington, DC: Institute of Medicine.
21. Ling, W. & Obert, J. L. (2000) Handbook for Recovery from Opiate Dependence Adapted from the Matrix Model, Version 1. (11/16/00). Available from the senior author upon request.
22. Lintzeris, N., Bell, J., Bammer, G., Jolley, D. J. & Rushworth, L. (2002) A randomized controlled trial of buprenorphine in the management of short-term ambulatory heroin withdrawal. Addiction, 97, 1395-1404.
23. McLellan, A. T., Kushner, H., Metzger, D., Peters, R., Smith, I., Grissom, G. et al. (1992) The fifth edition of the Addiction Severity Index. Journal of Substance Abuse Treatment, 9, 199-213.
24. Nigam, A. K., Ray, R. & Tripathy, B. M. (1993) Buprenorphine in opiate withdrawal: A comparison with clonidine. Journal of Substance Abuse Treatment, 10, 391-394.
25. Rawson, R. A., McCann, M. J., Shoptaw, S., Miotta, K., Frosch, D. L., Obert, J. L. et al. (2001) Naltrexone for opiate addiction: the evaluation of a manualized psychosocial protocol to enhance treatment response. Drug and Alcohol Review, 20, 69-80.
26. Wesson, D., R. & Ling, W. (2003) The Clinical Opiate Withdrawal Scale (COWS). Journal of Psychoactive Drugs, 35, 253-259.
27. Wesson, D., Ling, W. & Jara, G. (1999) Buprenorphine in pharmacotherapy of opioid addiction: implementation in office-based medical practice. Translating the experience of clinical trials into clinical practice. Newsletter of the California Society of Addiction Medicine, 25.