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Volumn 120, Issue 9, 1994, Pages 771-783

Selected treatment strategies for septic shock based on proposed mechanisms of pathogenesis

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; CENTOXIN; INTERLEUKIN 1; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY E5; NITRIC OXIDE; POLYCLONAL ANTIBODY; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

EID: 23444446083     PISSN: 00034819     EISSN: None     Source Type: Journal    
DOI: 10.7326/0003-4819-120-9-199405010-00009     Document Type: Conference Paper
Times cited : (418)

References (151)
  • 3
    • 0024575208 scopus 로고
    • Role of endotoxemia in cardiovascular dysfunction and mortality. Escherichia coli and Staphylococcus aureus challenges in a canine model of human septic shock
    • Natanson C, Danner RL, Elin RJ, Hosseini JM, Peart KW, Banks SM, et al. Role of endotoxemia in cardiovascular dysfunction and mortality. Escherichia coli and Staphylococcus aureus challenges in a canine model of human septic shock. J Clin Invest. 1989;83: 243-51.
    • (1989) J Clin Invest , vol.83 , pp. 243-251
    • Natanson, C.1    Danner, R.L.2    Elin, R.J.3    Hosseini, J.M.4    Peart, K.W.5    Banks, S.M.6
  • 4
    • 0026710191 scopus 로고
    • Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
    • The ACCP/SCCM Consensus Conference Committee
    • Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. Chest. 1992;101:1644-55.
    • (1992) Chest , vol.101 , pp. 1644-1655
    • Bone, R.C.1    Balk, R.A.2    Cerra, F.B.3    Dellinger, R.P.4    Fein, A.M.5    Knaus, W.A.6
  • 5
    • 0027916179 scopus 로고
    • The role of interleukin-1 in disease
    • Dinarello CA, Wolff SM. The role of interleukin-1 in disease. N Engl J Med. 1993;328:106-13.
    • (1993) N Engl J Med , vol.328 , pp. 106-113
    • Dinarello, C.A.1    Wolff, S.M.2
  • 6
    • 0025719982 scopus 로고
    • Cytokines in context
    • Nathan C, Sporn M. Cytokines in context. J Cell Biol. 1991;113: 981-6.
    • (1991) J Cell Biol , vol.113 , pp. 981-986
    • Nathan, C.1    Sporn, M.2
  • 7
    • 0023491364 scopus 로고
    • Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia
    • Tracey KJ, Fong Y, Hesse DG, Manogue KR, Lee AT, Kuo GC, et al. Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia. Nature. 1987;330:662-4.
    • (1987) Nature , vol.330 , pp. 662-664
    • Tracey, K.J.1    Fong, Y.2    Hesse, D.G.3    Manogue, K.R.4    Lee, A.T.5    Kuo, G.C.6
  • 8
    • 0019906260 scopus 로고
    • Treatment of gram-negative bacteremia and shock with human antiserum to a mutant Escherichia coli
    • Ziegler EJ, McCutchan JA, Fierer J, Glauser MP, Sadoff JC, Douglas H, et al. Treatment of gram-negative bacteremia and shock with human antiserum to a mutant Escherichia coli. N Engl J Med. 1982;307:1225-30.
    • (1982) N Engl J Med , vol.307 , pp. 1225-1230
    • Ziegler, E.J.1    McCutchan, J.A.2    Fierer, J.3    Glauser, M.P.4    Sadoff, J.C.5    Douglas, H.6
  • 10
    • 0026016470 scopus 로고
    • Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomized, double-blind, placebo-controlled trial
    • The HA-1A Sepsis Study Group
    • Ziegler EJ, Fisher CJ Jr, Sprung CL, Straube RC, Sadoff JC, Foulke GE, et al. Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomized, double-blind, placebo-controlled trial. The HA-1A Sepsis Study Group. N Engl J Med. 1991:324:429-36.
    • (1991) N Engl J Med , vol.324 , pp. 429-436
    • Ziegler, E.J.1    Fisher Jr., C.J.2    Sprung, C.L.3    Straube, R.C.4    Sadoff, J.C.5    Foulke, G.E.6
  • 11
    • 84989452188 scopus 로고
    • Efficacy of P.A.F. antagonist (BN 52021) in reducing mortality of patients with severe gram-negative sepsis
    • Tenaillon A, Dhainaut JF, Letulzo Y, Schlemmer B, Solet JP, Wolff M, et al. Efficacy of P.A.F. antagonist (BN 52021) in reducing mortality of patients with severe gram-negative sepsis [Abstract]. Am Rev Respir Dis. 1993;147:A196.
    • (1993) Am Rev Respir Dis , vol.147
    • Tenaillon, A.1    Dhainaut, J.F.2    Letulzo, Y.3    Schlemmer, B.4    Solet, J.P.5    Wolff, M.6
  • 12
    • 0023239471 scopus 로고
    • Effect of high-dose glucocorticoid therapy on mortality in patients with clinical signs of systemic sepsis
    • The Veterans Administration Systemic Sepsis Cooperative Study Group. Effect of high-dose glucocorticoid therapy on mortality in patients with clinical signs of systemic sepsis. N Engl J Med. 1987;317:659-65.
    • (1987) N Engl J Med , vol.317 , pp. 659-665
  • 13
    • 0025710312 scopus 로고
    • Increase in national hospital discharge survey rates for septicemia - United States, 1979-1987
    • Increase in national hospital discharge survey rates for septicemia - United States, 1979-1987. MMWR Morb Mortal Wkly Rep. 1990;39:31-4.
    • (1990) MMWR Morb Mortal Wkly Rep , vol.39 , pp. 31-34
  • 14
    • 0020652640 scopus 로고
    • Chemistry and immunochemistry of bacterial lipopolysaccharide as cell wall antigens and endotoxins
    • Westphal O, Jann K, Himmelspach K. Chemistry and immunochemistry of bacterial lipopolysaccharide as cell wall antigens and endotoxins. Prog Allergy. 1983;33:9-39.
    • (1983) Prog Allergy , vol.33 , pp. 9-39
    • Westphal, O.1    Jann, K.2    Himmelspach, K.3
  • 15
    • 0024520830 scopus 로고
    • Endotoxin and tumor necrosis factor challenges in dogs simulate the cardiovascular profile of human septic shock
    • Natanson C, Eichenholz PW, Danner RL, Eichacker PQ, Hoffman WD, Kuo GC, et al. Endotoxin and tumor necrosis factor challenges in dogs simulate the cardiovascular profile of human septic shock. J Exp Med. 1989;169:823-32.
    • (1989) J Exp Med , vol.169 , pp. 823-832
    • Natanson, C.1    Eichenholz, P.W.2    Danner, R.L.3    Eichacker, P.Q.4    Hoffman, W.D.5    Kuo, G.C.6
  • 17
    • 0014495006 scopus 로고
    • The role of endotoxin during typhoid fever and tularemia in man. IV. The integrity of the endotoxin tolerance mechanisms during infection
    • Greisman SE, Hornick RB, Wagner HN Jr, Woodward WE, Woodward TE. The role of endotoxin during typhoid fever and tularemia in man. IV. The integrity of the endotoxin tolerance mechanisms during infection. J Clin Invest. 1969;48:613-29.
    • (1969) J Clin Invest , vol.48 , pp. 613-629
    • Greisman, S.E.1    Hornick, R.B.2    Wagner Jr., H.N.3    Woodward, W.E.4    Woodward, T.E.5
  • 19
    • 8044222677 scopus 로고
    • Shock in gram-negative bacteremia: Predisposing factors, pathophysiology, and treatment
    • Remington JS, Swartz MN; eds. New York: McGraw-Hill
    • McCabe WR, Olans RN. Shock in gram-negative bacteremia: predisposing factors, pathophysiology, and treatment. In: Remington JS, Swartz MN; eds. Current Clinical Topics in Infectious Diseases. Vol. 2. New York: McGraw-Hill; 1981:121-50.
    • (1981) Current Clinical Topics in Infectious Diseases , vol.2 , pp. 121-150
    • McCabe, W.R.1    Olans, R.N.2
  • 20
    • 0021356048 scopus 로고
    • The importance of the K1 capsule in invasive infections caused by Escherichia coli
    • Cross AS, Gemski P, Sadoff JC, Orskov F, Orskov I. The importance of the K1 capsule in invasive infections caused by Escherichia coli. J Infect Dis. 1984;149:184-93.
    • (1984) J Infect Dis , vol.149 , pp. 184-193
    • Cross, A.S.1    Gemski, P.2    Sadoff, J.C.3    Orskov, F.4    Orskov, I.5
  • 21
    • 0021983322 scopus 로고
    • Characterization of mouse monoclonal antibodies directed against Pseudomonas aeruginosa lipopolysaccharides
    • Sadoff JC, Wright DC, Futrovsky S, Sidberry H, Collins H, Kaufmann B. Characterization of mouse monoclonal antibodies directed against Pseudomonas aeruginosa lipopolysaccharides. Antibiot Chemother. 1985;36:134-46.
    • (1985) Antibiot Chemother , vol.36 , pp. 134-146
    • Sadoff, J.C.1    Wright, D.C.2    Futrovsky, S.3    Sidberry, H.4    Collins, H.5    Kaufmann, B.6
  • 22
    • 0015795005 scopus 로고
    • Treatment of E. coli and klebsiella bacteremia in agranulocytic animals with antiserum to a UDP-gal epimerase-deficient mutant
    • Ziegler EJ, Douglas H, Sherman JE, Davis CE, Brande AI. Treatment of E. coli and klebsiella bacteremia in agranulocytic animals with antiserum to a UDP-gal epimerase-deficient mutant. J Immunol. 1973;111:433-8.
    • (1973) J Immunol , vol.111 , pp. 433-438
    • Ziegler, E.J.1    Douglas, H.2    Sherman, J.E.3    Davis, C.E.4    Brande, A.I.5
  • 23
    • 0016784897 scopus 로고
    • Functional role of antibody against core glycolipid of Enterobacteriaceae
    • Young LS, Stevens P, Ingram J. Functional role of antibody against core glycolipid of Enterobacteriaceae. J Clin Invest. 1975;56:850-61.
    • (1975) J Clin Invest , vol.56 , pp. 850-861
    • Young, L.S.1    Stevens, P.2    Ingram, J.3
  • 24
    • 0027411037 scopus 로고
    • Human anti-endotoxin antibody HA-1A mediates complement-dependent binding of Escherichia coli J5 lipopolysaccharide to complement receptor type 1 of human erythrocytes and neutrophils
    • Krieger JI, Fletcher RC, Siegel SA, Fearon DT, Neblock DS, Boutin RH, et al. Human anti-endotoxin antibody HA-1A mediates complement-dependent binding of Escherichia coli J5 lipopolysaccharide to complement receptor type 1 of human erythrocytes and neutrophils. J Infect Dis. 1993;167:865-75.
    • (1993) J Infect Dis , vol.167 , pp. 865-875
    • Krieger, J.I.1    Fletcher, R.C.2    Siegel, S.A.3    Fearon, D.T.4    Neblock, D.S.5    Boutin, R.H.6
  • 25
    • 0025804548 scopus 로고
    • Antibodies to core lipopolysaccharide determinants: Absence of cross-reactivity with heterologous lipopolysaccharides
    • Heumann D, Baumgartner JD, Jacot-Guillarmod H, Glauser M. Antibodies to core lipopolysaccharide determinants: absence of cross-reactivity with heterologous lipopolysaccharides. J Infect Dis. 1991;163:762-8.
    • (1991) J Infect Dis , vol.163 , pp. 762-768
    • Heumann, D.1    Baumgartner, J.D.2    Jacot-Guillarmod, H.3    Glauser, M.4
  • 26
    • 0017714630 scopus 로고
    • Immunization with R mutants of Salmonella minnesota. II. Comparison of the protective effect of immunization with lipid A and the Re mutant
    • Bruins SC, Stumacher R, Johns MA, McCabe WR. Immunization with R mutants of Salmonella minnesota. II. Comparison of the protective effect of immunization with lipid A and the Re mutant. Infect Immunol. 1977;17:16-20.
    • (1977) Infect Immunol , vol.17 , pp. 16-20
    • Bruins, S.C.1    Stumacher, R.2    Johns, M.A.3    McCabe, W.R.4
  • 28
    • 0027396598 scopus 로고
    • Assessment of ability of murine and human anti-lipid A monoclonal antibodies to bind and neutralize lipopolysaccharide
    • Warren HS, Amato SF, Pitting C, Black KM, Loiselle PM, Pasternack MS, et al. Assessment of ability of murine and human anti-lipid A monoclonal antibodies to bind and neutralize lipopolysaccharide. J Exp Med. 1993;177:89-97.
    • (1993) J Exp Med , vol.177 , pp. 89-97
    • Warren, H.S.1    Amato, S.F.2    Pitting, C.3    Black, K.M.4    Loiselle, P.M.5    Pasternack, M.S.6
  • 29
    • 0026293815 scopus 로고
    • Immunotherapy with antibodies to core lipopolysaccharide: A critical appraisal
    • Baumgartner JD. Immunotherapy with antibodies to core lipopolysaccharide: a critical appraisal. Infect Dis Clin North Am. 1991;5: 915-27.
    • (1991) Infect Dis Clin North Am , vol.5 , pp. 915-927
    • Baumgartner, J.D.1
  • 30
    • 0023678354 scopus 로고
    • Treatment of gram-negative septic shock with human IgG antibody to Escherichia coli J5: A prospective, double-blind, randomized trial
    • Calandra T, Glauser MP, Schellekens J, Verhoef J. Treatment of gram-negative septic shock with human IgG antibody to Escherichia coli J5: a prospective, double-blind, randomized trial. J Infect Dis. 1988;158:312-19.
    • (1988) J Infect Dis , vol.158 , pp. 312-319
    • Calandra, T.1    Glauser, M.P.2    Schellekens, J.3    Verhoef, J.4
  • 31
    • 0021077999 scopus 로고
    • Ineffectiveness of single-dose human antiserum to core glycolipid (E. coli J5) for prophylaxis of bacteremic, gram-negative infection in patients with prolonged neutropenia
    • McCutchan JA, Wolf JL, Ziegler EJ, Braude AI. Ineffectiveness of single-dose human antiserum to core glycolipid (E. coli J5) for prophylaxis of bacteremic, gram-negative infection in patients with prolonged neutropenia. Schweiz Med Wochenschr. 1983;113(Suppl 14):40-55.
    • (1983) Schweiz Med Wochenschr , vol.113 , Issue.14 SUPPL. , pp. 40-55
    • McCutchan, J.A.1    Wolf, J.L.2    Ziegler, E.J.3    Braude, A.I.4
  • 32
    • 0021843019 scopus 로고
    • Prevention of gram-negative shock and death in surgical patients by antibody to endotoxin core glycolipid
    • Baumgartner JD, Glauser MP, McCutchan JA, Ziegler EJ, van Melle G, Klauber MR, et al. Prevention of gram-negative shock and death in surgical patients by antibody to endotoxin core glycolipid. Lancet. 1985;2:59-63.
    • (1985) Lancet , vol.2 , pp. 59-63
    • Baumgartner, J.D.1    Glauser, M.P.2    McCutchan, J.A.3    Ziegler, E.J.4    Van Melle, G.5    Klauber, M.R.6
  • 33
    • 0026720270 scopus 로고
    • Prophylactic intravenous administration of standard immune globulin as compared with core-lipopolysaccharide immune globulin in patients at high risk of postsurgical infection
    • The Intravenous Immunoglobulin Collaborative Study Group. Prophylactic intravenous administration of standard immune globulin as compared with core-lipopolysaccharide immune globulin in patients at high risk of postsurgical infection. N Engl J Med. 1992; 327:234-40.
    • (1992) N Engl J Med , vol.327 , pp. 234-240
  • 34
    • 0026780301 scopus 로고
    • Treatment of severe infectious purpura in children with human plasma from donors immunized with Escherichia coli J5: A prospective double-blind study
    • J5 Study Group. Treatment of severe infectious purpura in children with human plasma from donors immunized with Escherichia coli J5: a prospective double-blind study. J Infect Dis. 1992;165:695-701.
    • (1992) J Infect Dis , vol.165 , pp. 695-701
  • 35
    • 0024762971 scopus 로고
    • Monoclonal antibodies for treatment of gram-negative infections
    • Young LS, Gascon R, Alam S, Bermudez LM. Monoclonal antibodies for treatment of gram-negative infections. Rev Infect Dis. 1989; 11(Suppl 7):S1564-71.
    • (1989) Rev Infect Dis , vol.11 , Issue.7 SUPPL.
    • Young, L.S.1    Gascon, R.2    Alam, S.3    Bermudez, L.M.4
  • 37
    • 0025043270 scopus 로고
    • Studies of an anti-endotoxin antibody in preventing the physiologic changes of endotoxemia in awake sheep
    • Wheeler AP, Hardie WD, Bernard G. Studies of an anti-endotoxin antibody in preventing the physiologic changes of endotoxemia in awake sheep. Am Rev Respir Dis. 1990;142:775-81.
    • (1990) Am Rev Respir Dis , vol.142 , pp. 775-781
    • Wheeler, A.P.1    Hardie, W.D.2    Bernard, G.3
  • 38
    • 0025350856 scopus 로고
    • Association between protective efficacy of anti-lipopolysaccharide (LPS) antibodies and suppression of LPS-induced tumor necrosis factor alpha and interleukin 6. Comparison of O side chain-specific antibodies with core LPS antibodies
    • Baumgartner JD, Heumann D, Gerain J, Weinbreck P, Grau GE, Glauser MP. Association between protective efficacy of anti-lipopolysaccharide (LPS) antibodies and suppression of LPS-induced tumor necrosis factor alpha and interleukin 6. Comparison of O side chain-specific antibodies with core LPS antibodies. J Exp Med. 1990;171:889-96.
    • (1990) J Exp Med , vol.171 , pp. 889-896
    • Baumgartner, J.D.1    Heumann, D.2    Gerain, J.3    Weinbreck, P.4    Grau, G.E.5    Glauser, M.P.6
  • 39
    • 0025917510 scopus 로고
    • A controlled clinical trial of E5 murine monoclonal IgM antibody to endotoxin in the treatment of gram-negative sepsis
    • The XOMA Sepsis Study Group
    • Greenman RL, Schein RM, Martin MA, Wenzel RP, MacIntyre NR, Emmanuel G, et al. A controlled clinical trial of E5 murine monoclonal IgM antibody to endotoxin in the treatment of gram-negative sepsis. The XOMA Sepsis Study Group. JAMA. 1991;266: 1097-1102.
    • (1991) JAMA. , vol.266 , pp. 1097-1102
    • Greenman, R.L.1    Schein, R.M.2    Martin, M.A.3    Wenzel, R.P.4    MacIntyre, N.R.5    Emmanuel, G.6
  • 41
    • 0025103882 scopus 로고
    • Editorial review of protocols for clinical trials [Editor's reply]
    • Relman AS. Editorial review of protocols for clinical trials [Editor's reply]. N Engl J Med. 1990;323:1355.
    • (1990) N Engl J Med , vol.323 , pp. 1355
    • Relman, A.S.1
  • 43
    • 0345206549 scopus 로고
    • Anti-endotoxin monoclonal antibodies [the FDA reply]
    • Siegel JP, Stein KE, Zoon KC. Anti-endotoxin monoclonal antibodies [the FDA reply]. N Engl J Med. 1992;327:890-1.
    • (1992) N Engl J Med , vol.327 , pp. 890-891
    • Siegel, J.P.1    Stein, K.E.2    Zoon, K.C.3
  • 44
    • 0027279973 scopus 로고
    • Introduction of new technology into critical care practice: A history of HA-1A human monoclonal antibody against endotoxin
    • Luce JM. Introduction of new technology into critical care practice: a history of HA-1A human monoclonal antibody against endotoxin. Crit Care Med. 1993;21:1233-41
    • (1993) Crit Care Med , vol.21 , pp. 1233-1241
    • Luce, J.M.1
  • 45
    • 0028115880 scopus 로고
    • Distinct functional activities in canine septic shock of monoclonal antibodies specific for the O-polysaccharide and core regions of Escherichia coli lipopolysaccharide
    • Hoffman WD, Pollack M, Banks SM, Koev LA, Solomon MA, Danner RL, et al. Distinct functional activities in canine septic shock of monoclonal antibodies specific for the O-polysaccharide and core regions of Escherichia coli lipopolysaccharide. J Infect Dis. 1994;169:553-61.
    • (1994) J Infect Dis , vol.169 , pp. 553-561
    • Hoffman, W.D.1    Pollack, M.2    Banks, S.M.3    Koev, L.A.4    Solomon, M.A.5    Danner, R.L.6
  • 46
    • 0027466909 scopus 로고
    • A controlled trial of HA-1A in a canine model of gram-negative septic shock
    • Quezado ZM, Natanson C, Alling DW, Banks SM, Koev CA, Elin RJ, et al. A controlled trial of HA-1A in a canine model of gram-negative septic shock. JAMA. 1993;269:2221-7.
    • (1993) JAMA , vol.269 , pp. 2221-2227
    • Quezado, Z.M.1    Natanson, C.2    Alling, D.W.3    Banks, S.M.4    Koev, C.A.5    Elin, R.J.6
  • 47
    • 0027481773 scopus 로고
    • Endotoxin as a therapeutic target in septic shock
    • Corriveau CC, Danner RL. Endotoxin as a therapeutic target in septic shock. Infect Agents Dis. 1993;2:35-43.
    • (1993) Infect Agents Dis , vol.2 , pp. 35-43
    • Corriveau, C.C.1    Danner, R.L.2
  • 48
    • 0024828720 scopus 로고
    • In vitro production of IL-1 beta, IL-1 alpha, TNF and IL-2 in healthy subjects: Distribution, effect of cyclooxygenase inhibition and evidence of independent gene regulation
    • Endres S, Cannon JG, Ghorbani R, Dempsey RA, Sisson SD, Lonnemann G, et al. In vitro production of IL-1 beta, IL-1 alpha, TNF and IL-2 in healthy subjects: distribution, effect of cyclooxygenase inhibition and evidence of independent gene regulation. Eur J Immunol. 1989;19:2327-33.
    • (1989) Eur J Immunol , vol.19 , pp. 2327-2333
    • Endres, S.1    Cannon, J.G.2    Ghorbani, R.3    Dempsey, R.A.4    Sisson, S.D.5    Lonnemann, G.6
  • 51
    • 0344140225 scopus 로고
    • Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition
    • Okusawa S, Gelfand JA, Ikejima T, Connolly RJ, Dinarello CA. Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition. J Clin Invest. 1988;81:1162-72.
    • (1988) J Clin Invest , vol.81 , pp. 1162-1172
    • Okusawa, S.1    Gelfand, J.A.2    Ikejima, T.3    Connolly, R.J.4    Dinarello, C.A.5
  • 53
    • 0026633556 scopus 로고
    • The toxic and hematologic effects of interleukin-1 alpha administered in a phase I trial to patients with advanced malignancies
    • Smith JW II, Urba WJ, Curti BD, Elwood LJ, Steis RG, Janik JE, et al. The toxic and hematologic effects of interleukin-1 alpha administered in a phase I trial to patients with advanced malignancies. J Clin Oncol. 1992;10:1141-52.
    • (1992) J Clin Oncol , vol.10 , pp. 1141-1152
    • Smith II, J.W.1    Urba, W.J.2    Curti, B.D.3    Elwood, L.J.4    Steis, R.G.5    Janik, J.E.6
  • 55
    • 0026772736 scopus 로고
    • Interleukin-1 receptor blockade improves survival and hemodynamic performance in Escherichia coli septic shock, but fails to alter host responses to sublethal endotoxemia
    • Fischer E, Marano MA, Van Zee KJ, Rock CS, Hawes AS, Thompson WA, et al. Interleukin-1 receptor blockade improves survival and hemodynamic performance in Escherichia coli septic shock, but fails to alter host responses to sublethal endotoxemia. J Clin Invest. 1992;89:1551-7.
    • (1992) J Clin Invest , vol.89 , pp. 1551-1557
    • Fischer, E.1    Marano, M.A.2    Van Zee, K.J.3    Rock, C.S.4    Hawes, A.S.5    Thompson, W.A.6
  • 56
    • 0022411888 scopus 로고
    • Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effects of endotoxin
    • Beutler B, Milsark IW, Cerami AC. Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effects of endotoxin. Science. 1985;229:869-71.
    • (1985) Science , vol.229 , pp. 869-871
    • Beutler, B.1    Milsark, I.W.2    Cerami, A.C.3
  • 57
    • 0026056197 scopus 로고
    • Blocking IL-1: Interleukin 1 receptor antagonist in vivo and in vitro
    • Dinarello CA, Thompson RC. Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro. Immunol Today. 1991:12:404-10.
    • (1991) Immunol Today , vol.12 , pp. 404-410
    • Dinarello, C.A.1    Thompson, R.C.2
  • 58
    • 0025266645 scopus 로고
    • Prognostic values of tumor necrosis factor/ cachectin, interleukin-1, interferon-α, and interferon-γ in the serum of patients with septic shock
    • Calandra T, Baumgartner JD, Grau GE, Wu MM, Lambert PH, Schellekens J, et al. Prognostic values of tumor necrosis factor/ cachectin, interleukin-1, interferon-α, and interferon-γ in the serum of patients with septic shock. J Infect Dis. 1990;161:982-7.
    • (1990) J Infect Dis , vol.161 , pp. 982-987
    • Calandra, T.1    Baumgartner, J.D.2    Grau, G.E.3    Wu, M.M.4    Lambert, P.H.5    Schellekens, J.6
  • 60
    • 0024529891 scopus 로고
    • The complex pattern of cytokines in serum from patients with meningococcal septic shock
    • Waage A, Brandtzaeg P, Halstensen A, Kierulf P, Espevik T. The complex pattern of cytokines in serum from patients with meningococcal septic shock. J Exp Med 1989;169:333-8.
    • (1989) J Exp Med , vol.169 , pp. 333-338
    • Waage, A.1    Brandtzaeg, P.2    Halstensen, A.3    Kierulf, P.4    Espevik, T.5
  • 61
    • 0026787392 scopus 로고
    • High bronchoalveolar levels of tumor necrosis factor and its inhibitors, interleukin-1, interferon, and elastase, in patients with adult respiratory distress syndrome after trauma, shock, or sepsis
    • Suter PM, Suter S, Girardin E, Roux-Lombard P, Grau GE, Dayer JM. High bronchoalveolar levels of tumor necrosis factor and its inhibitors, interleukin-1, interferon, and elastase, in patients with adult respiratory distress syndrome after trauma, shock, or sepsis. Am Rev Respir Dis. 1992;145:1016-22.
    • (1992) Am Rev Respir Dis , vol.145 , pp. 1016-1022
    • Suter, P.M.1    Suter, S.2    Girardin, E.3    Roux-Lombard, P.4    Grau, G.E.5    Dayer, J.M.6
  • 62
    • 0027215981 scopus 로고
    • Compartmentalization of the acute cytokine response in humans after intravenous endotoxin administration
    • Boujoukos AJ, Martich GD, Supinski E, Suffredini AF. Compartmentalization of the acute cytokine response in humans after intravenous endotoxin administration. J Appl Physiol. 1993;74:3027-33.
    • (1993) J Appl Physiol , vol.74 , pp. 3027-3033
    • Boujoukos, A.J.1    Martich, G.D.2    Supinski, E.3    Suffredini, A.F.4
  • 63
    • 0026758069 scopus 로고
    • Regulation of tumor necrosis factor receptors on phagocytes
    • Ding AH, Porteu F. Regulation of tumor necrosis factor receptors on phagocytes. Proc Soc Exp Biol Med. 1992;200:458-65.
    • (1992) Proc Soc Exp Biol Med , vol.200 , pp. 458-465
    • Ding, A.H.1    Porteu, F.2
  • 64
    • 0026516744 scopus 로고
    • Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors
    • Aderka D, Engelmann H, Maor Y, Brakebusch C, Wallach D. Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors. J Exp Med. 1992;175:323-9.
    • (1992) J Exp Med , vol.175 , pp. 323-329
    • Aderka, D.1    Engelmann, H.2    Maor, Y.3    Brakebusch, C.4    Wallach, D.5
  • 65
    • 0026058710 scopus 로고
    • Soluble cytokine receptors: Their role in immunoregulation
    • Fernandez-Botran R. Soluble cytokine receptors: their role in immunoregulation. FASEB J. 1991;5:2567-74.
    • (1991) FASEB J , vol.5 , pp. 2567-2574
    • Fernandez-Botran, R.1
  • 66
    • 0026741275 scopus 로고
    • Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor in vitro and in vivo
    • Van Zee KJ, Kohno T, Fischer E, Rock CS, Moldawer LL, Lowry SF. Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor in vitro and in vivo. Proc Natl Acad Sci USA. 1992;89:4845-9.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 4845-4849
    • Van Zee, K.J.1    Kohno, T.2    Fischer, E.3    Rock, C.S.4    Moldawer, L.L.5    Lowry, S.F.6
  • 67
    • 0026753370 scopus 로고
    • Interleukin-1 receptor antagonist circulates in experimental inflammation and in human disease
    • Fischer E, Van Zee KJ, Marano MA, Rock CS, Kenney JS, Poutsiaka DD, et al. Interleukin-1 receptor antagonist circulates in experimental inflammation and in human disease. Blood. 1992;79: 2196-2200.
    • (1992) Blood , vol.79 , pp. 2196-2200
    • Fischer, E.1    Van Zee, K.J.2    Marano, M.A.3    Rock, C.S.4    Kenney, J.S.5    Poutsiaka, D.D.6
  • 68
    • 0026006260 scopus 로고
    • The proinflammatory cytokines interleukin-1 and tumor necrosis factor and treatment of septic shock syndrome
    • Dinarello CA. The proinflammatory cytokines interleukin-1 and tumor necrosis factor and treatment of septic shock syndrome. J Infect Dis. 1991;163:1177-84.
    • (1991) J Infect Dis , vol.163 , pp. 1177-1184
    • Dinarello, C.A.1
  • 69
    • 0023736957 scopus 로고
    • Endogenous tumor necrosis factor (cachectin) is essential to host resistance against Listeria monocytogenes infection
    • Nakane A, Minagawa T, Kato K. Endogenous tumor necrosis factor (cachectin) is essential to host resistance against Listeria monocytogenes infection. Infect Immunol. 1988;56:2563-9.
    • (1988) Infect Immunol , vol.56 , pp. 2563-2569
    • Nakane, A.1    Minagawa, T.2    Kato, K.3
  • 71
    • 0025893127 scopus 로고
    • Treatment with recombinant human tumor necrosis factor-alpha protects rats against the lethality, hypotension, and hypothermia of gram-negative sepsis
    • Alexander HR, Sheppard BC, Jensen JC, Langstein HN, Buresh CM, Venzon D, et al. Treatment with recombinant human tumor necrosis factor-alpha protects rats against the lethality, hypotension, and hypothermia of gram-negative sepsis. J Clin Invest. 1991; 88:34-9.
    • (1991) J Clin Invest , vol.88 , pp. 34-39
    • Alexander, H.R.1    Sheppard, B.C.2    Jensen, J.C.3    Langstein, H.N.4    Buresh, C.M.5    Venzon, D.6
  • 72
    • 0023878325 scopus 로고
    • A low dose of recombinant interleukin 1 protects granulocytopenic mice from lethal gram-negative infection
    • Van der Meer JW, Barza M, Wolff SM, Dinarello CA. A low dose of recombinant interleukin 1 protects granulocytopenic mice from lethal gram-negative infection. Proc Natl Acad Sci USA. 1988;85: 1620-3.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 1620-1623
    • Van Der Meer, J.W.1    Barza, M.2    Wolff, S.M.3    Dinarello, C.A.4
  • 75
    • 0026481128 scopus 로고
    • Lethal Staphylococcus aureus-induced shock in primates: Prevention of death with anti-TNF antibody
    • Hinshaw LB, Emerson TE, Taylor FB Jr, Chang AC, Duerr M, Peer GT, et al. Lethal Staphylococcus aureus-induced shock in primates: prevention of death with anti-TNF antibody. J Trauma. 1992;33:568-73.
    • (1992) J Trauma , vol.33 , pp. 568-573
    • Hinshaw, L.B.1    Emerson, T.E.2    Taylor Jr., F.B.3    Chang, A.C.4    Duerr, M.5    Peer, G.T.6
  • 77
    • 0026568118 scopus 로고
    • Cytokine production after intravenous or peritoneal gram-negative bacterial challenge in mice: Comparative efficacy of antibodies to tumor necrosis factor-α and to lipopolysaccharide
    • Zanetti G, Heumann D, Gérain J, Kohler J, Abbet P, Barras C, et al. Cytokine production after intravenous or peritoneal gram-negative bacterial challenge in mice: comparative efficacy of antibodies to tumor necrosis factor-α and to lipopolysaccharide. J Immunol. 1992;148:1890-7.
    • (1992) J Immunol , vol.148 , pp. 1890-1897
    • Zanetti, G.1    Heumann, D.2    Gérain, J.3    Kohler, J.4    Abbet, P.5    Barras, C.6
  • 78
    • 0025258906 scopus 로고
    • Requirement of endogenous tumor necrosis factor/cachectin for recovery from experimental peritonitis
    • Echtenacher B, Falk W, Mannel DN, Krammer PH. Requirement of endogenous tumor necrosis factor/cachectin for recovery from experimental peritonitis. J Immunol. 1990;145:3762-6.
    • (1990) J Immunol , vol.145 , pp. 3762-3766
    • Echtenacher, B.1    Falk, W.2    Mannel, D.N.3    Krammer, P.H.4
  • 79
    • 0026079224 scopus 로고
    • Divergent efficacy of antibody to tumor necrosis factor-α in intravascular and peritonitis models of sepsis
    • Bagby GJ, Plessala KJ, Wilson LA, Thompson JJ, Nelson S. Divergent efficacy of antibody to tumor necrosis factor-α in intravascular and peritonitis models of sepsis. J Infect Dis. 1991;163:83-8.
    • (1991) J Infect Dis , vol.163 , pp. 83-88
    • Bagby, G.J.1    Plessala, K.J.2    Wilson, L.A.3    Thompson, J.J.4    Nelson, S.5
  • 80
    • 0006397809 scopus 로고
    • Monoclonal antibody to human tumor necrosis factor (TNF MAb): Multicenter efficacy and safety study in patients with the sepsis syndrome
    • American Society for Microbiology, New Orleans, Louisiana, 17-20 October Abstract #696
    • Wherry J, Wenzel R, Wunderink R, Silverman H, Perl T, Nasraway S. et al. Monoclonal antibody to human tumor necrosis factor (TNF MAb): multicenter efficacy and safety study in patients with the sepsis syndrome. Presented at the 33rd Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, New Orleans, Louisiana, 17-20 October 1993, Abstract #696:246.
    • (1993) 33rd Interscience Conference on Antimicrobial Agents and Chemotherapy , pp. 246
    • Wherry, J.1    Wenzel, R.2    Wunderink, R.3    Silverman, H.4    Perl, T.5    Nasraway, S.6
  • 82
    • 0028018567 scopus 로고
    • Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: A randomized, open-label, placebo-controlled multicenter trial
    • Fisher CJ Jr, Slotner GJ, Opal SM, Pribble JP, Bone RC, Emmanuel G, et al. Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: a randomized, open-label, placebo-controlled multicenter trial. Crit Care Med. 1994;22:12-21.
    • (1994) Crit Care Med , vol.22 , pp. 12-21
    • Fisher Jr., C.J.1    Slotner, G.J.2    Opal, S.M.3    Pribble, J.P.4    Bone, R.C.5    Emmanuel, G.6
  • 83
    • 4243422671 scopus 로고
    • A study evaluating the safety and efficacy of human recombinant interleukin-1 receptor antagonist in the treatment of patients with sepsis syndrome: Preliminary results from a phase III multicenter trial
    • Fisher CJ Jr, Dhainaut J-F, Pribble JP, Knaus WA, IL-1 Receptor Antagonist Study Group. A study evaluating the safety and efficacy of human recombinant interleukin-1 receptor antagonist in the treatment of patients with sepsis syndrome: preliminary results from a phase III multicenter trial [Abstract]. Clin Intensive Care. 1993;4:8S.
    • (1993) Clin Intensive Care , vol.4
    • Fisher Jr., C.J.1    Dhainaut, J.-F.2    Pribble, J.P.3    Knaus, W.A.4
  • 84
    • 0027180430 scopus 로고
    • The clinical evaluation of new drugs for sepsis: A prospective study design based on survival analysis
    • Knaus VVA, Harrell FE, Fisher CJ Jr, Wagner DP, Opal SM, Sadoff JC, et al. The clinical evaluation of new drugs for sepsis: a prospective study design based on survival analysis. JAMA. 1993;270: 1233-41.
    • (1993) JAMA , vol.270 , pp. 1233-1241
    • Knaus, V.V.A.1    Harrell, F.E.2    Fisher Jr., C.J.3    Wagner, D.P.4    Opal, S.M.5    Sadoff, J.C.6
  • 85
    • 0026502629 scopus 로고
    • Inflammatory host responses in sepsis
    • Zimmerman JJ, Ringer TV. Inflammatory host responses in sepsis. Crit Care Clin. 1992;8:163-89.
    • (1992) Crit Care Clin , vol.8 , pp. 163-189
    • Zimmerman, J.J.1    Ringer, T.V.2
  • 86
    • 0025204719 scopus 로고
    • Mechanisms and mediators of the adult respiratory distress syndrome
    • Rinaldo JE, Christman JW. Mechanisms and mediators of the adult respiratory distress syndrome. Clin Chest Med. 1990;11:621-32.
    • (1990) Clin Chest Med , vol.11 , pp. 621-632
    • Rinaldo, J.E.1    Christman, J.W.2
  • 87
    • 0024590677 scopus 로고
    • Acute lung injury in septic shock
    • Bersten A, Sibbald WJ. Acute lung injury in septic shock. Crit Care Clin. 1989;5:49-77.
    • (1989) Crit Care Clin , vol.5 , pp. 49-77
    • Bersten, A.1    Sibbald, W.J.2
  • 88
    • 0024602827 scopus 로고
    • Tissue destruction by neutrophils
    • Weiss SJ. Tissue destruction by neutrophils. N Engl J Med. 1989; 320:365-76.
    • (1989) N Engl J Med , vol.320 , pp. 365-376
    • Weiss, S.J.1
  • 89
    • 0019846903 scopus 로고
    • Prevention by granulocyte depletion of increased vascular permeability of sheep lung following endotoxemia
    • Heflin AC Jr, Brigham KL. Prevention by granulocyte depletion of increased vascular permeability of sheep lung following endotoxemia. J Clin Invest. 1981;68:1253-60.
    • (1981) J Clin Invest , vol.68 , pp. 1253-1260
    • Heflin Jr., A.C.1    Brigham, K.L.2
  • 90
    • 0001815695 scopus 로고
    • Granulocytic phagocytes
    • Mandell GL, Douglas RG, Benett JE; eds. New York: Churchill Livingstone
    • Densen P, Mandell G. Granulocytic phagocytes. In: Mandell GL, Douglas RG, Benett JE; eds. Principles and Practice of Infectious Diseases. 3rd ed. New York: Churchill Livingstone; 1990:81-101.
    • (1990) Principles and Practice of Infectious Diseases. 3rd Ed. , pp. 81-101
    • Densen, P.1    Mandell, G.2
  • 91
    • 0026387814 scopus 로고
    • Neutrophils and adult respiratory distress syndrome: Two interlocking perspectives in 1991
    • Repine JE, Bechler CJ. Neutrophils and adult respiratory distress syndrome: two interlocking perspectives in 1991. Am Rev Resp Dis. 1991;144:251-2.
    • (1991) Am Rev Resp Dis , vol.144 , pp. 251-252
    • Repine, J.E.1    Bechler, C.J.2
  • 93
    • 0003015052 scopus 로고
    • Gram-negative sepsis
    • Mandell GL, Douglas RG, Benett JE; eds. New York: Churchill Livingstone
    • Young LS. Gram-negative sepsis. In: Mandell GL, Douglas RG, Benett JE; eds. Principles and Practice of Infectious Diseases. 3rd ed. New York: Churchill Livingstone; 1990:611-36.
    • (1990) Principles and Practice of Infectious Diseases. 3rd Ed. , pp. 611-636
    • Young, L.S.1
  • 94
    • 0025154326 scopus 로고
    • Biological effects and clinical applications of human colony-stimulating factors
    • Gabrilove JL, Jakubowski A. Biological effects and clinical applications of human colony-stimulating factors. Cancer Chemother Biol Response Modif. 1990;11:631-62.
    • (1990) Cancer Chemother Biol Response Modif , vol.11 , pp. 631-662
    • Gabrilove, J.L.1    Jakubowski, A.2
  • 95
    • 0025255615 scopus 로고
    • Structure and function of the leukocyte adhesion molecule CD11/CD18
    • Arnaout MA. Structure and function of the leukocyte adhesion molecule CD11/CD18. Blood. 1990;75:1037-50.
    • (1990) Blood , vol.75 , pp. 1037-1050
    • Arnaout, M.A.1
  • 96
    • 0022612240 scopus 로고
    • An endothelial cell surface factor(s) induced in vitro by lipopolysaccharide, interleukin-1, and tumor necrosis factor-alpha increases neutrophil adherence by a CDw18-dependent mechanism
    • Pohlman TH, Stanness KA, Beatty PG, Ochs HD, Harlan JM. An endothelial cell surface factor(s) induced in vitro by lipopolysaccharide, interleukin-1, and tumor necrosis factor-alpha increases neutrophil adherence by a CDw18-dependent mechanism. J Immunol. 1986;136:4548-53.
    • (1986) J Immunol , vol.136 , pp. 4548-4553
    • Pohlman, T.H.1    Stanness, K.A.2    Beatty, P.G.3    Ochs, H.D.4    Harlan, J.M.5
  • 97
    • 0025230704 scopus 로고
    • CD18-dependent and independent mechanisms of neutrophil emigration in the pulmonary and systemic microcirculation of rabbits
    • Doerschuk CM, Winn RK, Coxson HO, Harlan JM. CD18-dependent and independent mechanisms of neutrophil emigration in the pulmonary and systemic microcirculation of rabbits. J Immunol. 1990;144:2327-33.
    • (1990) J Immunol , vol.144 , pp. 2327-2333
    • Doerschuk, C.M.1    Winn, R.K.2    Coxson, H.O.3    Harlan, J.M.4
  • 98
    • 0025836764 scopus 로고
    • Involvement of the CD11b/18 integrin, but not of the endothelial cell adhesion molecules ELAM-1 and ICAM-1 in tumor necrosis factor alpha-induced neutrophil toxicity
    • Von Asmuth EJ, Van Der Linden CJ, Leeuwenberg JF, Buurman WA. Involvement of the CD11b/18 integrin, but not of the endothelial cell adhesion molecules ELAM-1 and ICAM-1 in tumor necrosis factor alpha-induced neutrophil toxicity. J Immunol. 1991; 147:3869-75.
    • (1991) J Immunol , vol.147 , pp. 3869-3875
    • Von Asmuth, E.J.1    Van Der Linden, C.J.2    Leeuwenberg, J.F.3    Buurman, W.A.4
  • 100
  • 101
    • 0026329185 scopus 로고
    • A CD18 monoclonal antibody increases the incidence and severity of subcutaneous abscess formation after high-dose staphylococcus aureus injection in rabbits
    • Sharrar SR, Winn RK, Nurry CE, Harlan JM, Rice CL. A CD18 monoclonal antibody increases the incidence and severity of subcutaneous abscess formation after high-dose staphylococcus aureus injection in rabbits. Surgery. 1991;110:213-20.
    • (1991) Surgery , vol.110 , pp. 213-220
    • Sharrar, S.R.1    Winn, R.K.2    Nurry, C.E.3    Harlan, J.M.4    Rice, C.L.5
  • 102
    • 0026353927 scopus 로고
    • Anti-CD18 antibody attenuates neutropenia and alveolar-capillary membrane injury during gram-negative sepsis
    • Walsh CJ, Carey PD, Cook DJ, Bechard DE, Fowler AA, Sugerman HJ. Anti-CD18 antibody attenuates neutropenia and alveolar-capillary membrane injury during gram-negative sepsis. Surgery. 1991; 110:205-12.
    • (1991) Surgery , vol.110 , pp. 205-212
    • Walsh, C.J.1    Carey, P.D.2    Cook, D.J.3    Bechard, D.E.4    Fowler, A.A.5    Sugerman, H.J.6
  • 103
    • 0026806891 scopus 로고
    • Leukocyte CD11b/18 antigen-directed monoclonal antibody improves early survival and decreases hypoxemia in dogs challenged with tumor necrosis factor
    • Eichacker PQ, Hoffman WD, Farese A, Bank SM, Mouginis T, Richmond S, et al. Leukocyte CD11b/18 antigen-directed monoclonal antibody improves early survival and decreases hypoxemia in dogs challenged with tumor necrosis factor. Am Rev Respir Dis. 1992;145:1023-9.
    • (1992) Am Rev Respir Dis , vol.145 , pp. 1023-1029
    • Eichacker, P.Q.1    Hoffman, W.D.2    Farese, A.3    Bank, S.M.4    Mouginis, T.5    Richmond, S.6
  • 104
    • 0025934206 scopus 로고
    • TNF but not IL-1 in dogs causes lethal lung injury and multiple organ dysfunction similar to human sepsis
    • Eichacker PQ, Hoffman WD, Farese A, Banks SM, Kuo GC, MacVittie TJ, et al. TNF but not IL-1 in dogs causes lethal lung injury and multiple organ dysfunction similar to human sepsis. J Appl Physiol. 1991;71:1979-89.
    • (1991) J Appl Physiol , vol.71 , pp. 1979-1989
    • Eichacker, P.Q.1    Hoffman, W.D.2    Farese, A.3    Banks, S.M.4    Kuo, G.C.5    MacVittie, T.J.6
  • 105
    • 0027229171 scopus 로고
    • Leukocyte CD18 monoclonal antibody worsens endotoxemia and cardiovascular injury in canines with septic shock
    • Eichacker PQ, Hoffman WD, Farese A, Danner RL, Suffredini AF, Waisman Y, et al. Leukocyte CD18 monoclonal antibody worsens endotoxemia and cardiovascular injury in canines with septic shock. J Appl Physiol. 1993;74:1885-92.
    • (1993) J Appl Physiol , vol.74 , pp. 1885-1892
    • Eichacker, P.Q.1    Hoffman, W.D.2    Farese, A.3    Danner, R.L.4    Suffredini, A.F.5    Waisman, Y.6
  • 107
    • 0025983150 scopus 로고
    • Granulocyte colony-stimulating factor enhances pulmonary host defenses in normal and ethanol-treated rats
    • Nelson S, Summer W, Bagby G, Nakamura C, Stewart L, Lipscomb G, et al. Granulocyte colony-stimulating factor enhances pulmonary host defenses in normal and ethanol-treated rats. J Infect Dis. 1991;164:901-6.
    • (1991) J Infect Dis , vol.164 , pp. 901-906
    • Nelson, S.1    Summer, W.2    Bagby, G.3    Nakamura, C.4    Stewart, L.5    Lipscomb, G.6
  • 108
    • 0025202849 scopus 로고
    • Seven-day administration of recombinant human granulocyte colony stimulating factor to newborn rats: Modulation of neonatal neutrophilia, myelopoieses, and group B streptococcus sepsis
    • Cairo MS, Plunkett JM, Mauss D, Van de ven C. Seven-day administration of recombinant human granulocyte colony stimulating factor to newborn rats: modulation of neonatal neutrophilia, myelopoieses, and group B streptococcus sepsis. Blood. 1990;76:1788-94.
    • (1990) Blood , vol.76 , pp. 1788-1794
    • Cairo, M.S.1    Plunkett, J.M.2    Mauss, D.3    Van De Ven, C.4
  • 109
    • 0023684832 scopus 로고
    • Recombinant human granulocyte colony-stimulating factor and pseudomonas burn wound sepsis
    • Mooney DP, Gamelli RL, O'Reilley M, Hebert JC. Recombinant human granulocyte colony-stimulating factor and pseudomonas burn wound sepsis. Arch Surg. 1988;123:1353-7.
    • (1988) Arch Surg , vol.123 , pp. 1353-1357
    • Mooney, D.P.1    Gamelli, R.L.2    O'Reilley, M.3    Hebert, J.C.4
  • 110
    • 2642590310 scopus 로고
    • Recombinant granulocyte colony stimulating factor reduces endotoxemia and improves cardiovascular function and survival during bacterial sepsis in non-neutropenic canines
    • Eichacker PQ, Waisman Y, Natanson C, Farese A, Hoffman WD, Banks SM, et al. Recombinant granulocyte colony stimulating factor reduces endotoxemia and improves cardiovascular function and survival during bacterial sepsis in non-neutropenic canines [Abstract]. Clin Res. 1993;41:240.
    • (1993) Clin Res , vol.41 , pp. 240
    • Eichacker, P.Q.1    Waisman, Y.2    Natanson, C.3    Farese, A.4    Hoffman, W.D.5    Banks, S.M.6
  • 111
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • Moncada S, Palmer RM, Higgs EA. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev. 1991;43:109-42.
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.2    Higgs, E.A.3
  • 112
    • 0024296032 scopus 로고
    • Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain
    • Garthwaite J, Charles SL, Chess-Williams R. Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain. Nature. 1988;336: 385-8.
    • (1988) Nature , vol.336 , pp. 385-388
    • Garthwaite, J.1    Charles, S.L.2    Chess-Williams, R.3
  • 113
    • 0023198721 scopus 로고
    • Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
    • Palmer RM, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature. 1987;327:524-6.
    • (1987) Nature , vol.327 , pp. 524-526
    • Palmer, R.M.1    Ferrige, A.G.2    Moncada, S.3
  • 114
    • 0025366847 scopus 로고
    • An L-arginine/nitric oxide pathway present in human platelets regulates aggregation
    • Radomski MW, Palmer RM, Moncada S. An L-arginine/nitric oxide pathway present in human platelets regulates aggregation. Proc Natl Acad Sci USA. 1990;87:5193-7.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 5193-5197
    • Radomski, M.W.1    Palmer, R.M.2    Moncada, S.3
  • 115
    • 0025731835 scopus 로고
    • Nitric oxide: An endogenous modulator of leukocyte adhesion
    • Kubes P, Suzuki M, Granger DN. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci USA. 1991; 88:4651-5.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 4651-4655
    • Kubes, P.1    Suzuki, M.2    Granger, D.N.3
  • 116
    • 0026034432 scopus 로고
    • Role of nitric oxide synthesis in macrophage antimicrobial activity
    • Nathan C, Hibbs JB Jr. Role of nitric oxide synthesis in macrophage antimicrobial activity. Curr Opin Immunol. 1991;3:65-70.
    • (1991) Curr Opin Immunol , vol.3 , pp. 65-70
    • Nathan, C.1    Hibbs Jr., J.B.2
  • 117
    • 0027202190 scopus 로고
    • Nitric oxide as a target for therapy in septic shock
    • Cobb JP, Cunnion RE, Danner RL. Nitric oxide as a target for therapy in septic shock. Crit Care Med. 1993;21:1261-3.
    • (1993) Crit Care Med , vol.21 , pp. 1261-1263
    • Cobb, J.P.1    Cunnion, R.E.2    Danner, R.L.3
  • 118
    • 0026629902 scopus 로고
    • Nitric oxide as a secretory product of mammalian cells
    • Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J. 1992;6:3051-64.
    • (1992) FASEB J , vol.6 , pp. 3051-3064
    • Nathan, C.1
  • 120
    • 0025943425 scopus 로고
    • Cytokine-activated endothelial cells express an isotype of nitric oxide synthase which is tetrahydrobiopterin-dependent, calmodulin-independent and inhibited by arginine analogs with a rank-order of potency characteristic of activated macrophages
    • Gross SS, Jaffe EA, Levi R, Kilbourn RG. Cytokine-activated endothelial cells express an isotype of nitric oxide synthase which is tetrahydrobiopterin-dependent, calmodulin-independent and inhibited by arginine analogs with a rank-order of potency characteristic of activated macrophages. Biochem Biophys Res Commun. 1991; 178:823-9.
    • (1991) Biochem Biophys Res Commun , vol.178 , pp. 823-829
    • Gross, S.S.1    Jaffe, E.A.2    Levi, R.3    Kilbourn, R.G.4
  • 121
    • 0025973551 scopus 로고
    • Interleukin-1 induces prolonged L-arginine-dependent cyclic guanosine monophosphate and nitrite production in rat vascular smooth muscle cells
    • Beasley D, Schwartz JH, Brenner BM. Interleukin-1 induces prolonged L-arginine-dependent cyclic guanosine monophosphate and nitrite production in rat vascular smooth muscle cells. J Clin Invest. 1991;87:602-8.
    • (1991) J Clin Invest , vol.87 , pp. 602-608
    • Beasley, D.1    Schwartz, J.H.2    Brenner, B.M.3
  • 123
    • 0026605238 scopus 로고
    • Evidence of cytokine-inducible nitric oxide synthesis from L-arginine in patients receiving interleukin-2 therapy
    • Hibbs JB Jr, Westenfelder C, Taintor R, Vavrin Z, Kablitz C, Baranowski RL, et al. Evidence of cytokine-inducible nitric oxide synthesis from L-arginine in patients receiving interleukin-2 therapy. J Clin Invest. 1992;89:867-77.
    • (1992) J Clin Invest , vol.89 , pp. 867-877
    • Hibbs Jr., J.B.1    Westenfelder, C.2    Taintor, R.3    Vavrin, Z.4    Kablitz, C.5    Baranowski, R.L.6
  • 127
    • 0026674684 scopus 로고
    • Nω-Amino-L-arginine, an inhibitor of nitric oxide synthase, raises vascular resistance but increases mortality rates in awake canines challenged with endotoxin
    • Cobb JP, Natanson C, Banks SM, Koev CA, Solomon MA, Hoffman WD, et al. Nω-Amino-L-arginine, an inhibitor of nitric oxide synthase, raises vascular resistance but increases mortality rates in awake canines challenged with endotoxin. J Exp Med. 1992;176: 1175-82.
    • (1992) J Exp Med , vol.176 , pp. 1175-1182
    • Cobb, J.P.1    Natanson, C.2    Banks, S.M.3    Koev, C.A.4    Solomon, M.A.5    Hoffman, W.D.6
  • 130
    • 9244255823 scopus 로고
    • Nitric oxide (NO) increases endotoxin (LPS)-induced cytokine production by human neutrophils (PMNs)
    • Van Dervort AL, Yan L, Madara PJ, Cobb JP, Wesley RA, Tropea MM, et al. Nitric oxide (NO) increases endotoxin (LPS)-induced cytokine production by human neutrophils (PMNs) [Abstract]. Clin Res. 1993;41:281.
    • (1993) Clin Res , vol.41 , pp. 281
    • Van Dervort, A.L.1    Yan, L.2    Madara, P.J.3    Cobb, J.P.4    Wesley, R.A.5    Tropea, M.M.6
  • 132
    • 0025925235 scopus 로고
    • G-monomethyl-L-arginine (NMA) restores arterial blood pressure but reduces cardiac output in a canine model of endotoxin shock
    • G-monomethyl-L-arginine (NMA) restores arterial blood pressure but reduces cardiac output in a canine model of endotoxin shock. Biochem Biophys Res Commun. 1991;178:1135-40.
    • (1991) Biochem Biophys Res Commun , vol.178 , pp. 1135-1140
    • Klabunde, R.E.1    Ritger, R.C.2
  • 133
    • 0027467022 scopus 로고
    • Selective inhibition of endothelium-dependent vasodilator capacity by Escherichia coli endotoxemia
    • Parker JL, Adams HR. Selective inhibition of endothelium-dependent vasodilator capacity by Escherichia coli endotoxemia. Circ Res. 1993;72:539-51.
    • (1993) Circ Res , vol.72 , pp. 539-551
    • Parker, J.L.1    Adams, H.R.2
  • 135
    • 0026016313 scopus 로고
    • The role of nitric oxide as an endogenous regulator of platelet and neutrophil activation within the pulmonary circulation of the rabbit
    • May GR, Crook P, Moore PK, Page CP. The role of nitric oxide as an endogenous regulator of platelet and neutrophil activation within the pulmonary circulation of the rabbit. Br J Pharmacol. 1991;102:759-63.
    • (1991) Br J Pharmacol , vol.102 , pp. 759-763
    • May, G.R.1    Crook, P.2    Moore, P.K.3    Page, C.P.4
  • 136
    • 0023607880 scopus 로고
    • Serial cardiovascular variables in survivors and nonsurvivors of human septic shock: Heart rate as an early predictor of prognosis
    • Parker MM, Shelbamer JH, Natanson C, Alling DW, Parrillo JE. Serial cardiovascular variables in survivors and nonsurvivors of human septic shock: heart rate as an early predictor of prognosis. Crit Care Med. 1987;15:923-9.
    • (1987) Crit Care Med , vol.15 , pp. 923-929
    • Parker, M.M.1    Shelbamer, J.H.2    Natanson, C.3    Alling, D.W.4    Parrillo, J.E.5
  • 137
    • 0027477592 scopus 로고
    • Nitric oxide synthase inhibition reverses arteriolar hyporesponsiveness to catecholamines in septic rats
    • Heart Circ Physiol
    • Hollenberg SM, Cunnion RE, Zimmerberg J. Nitric oxide synthase inhibition reverses arteriolar hyporesponsiveness to catecholamines in septic rats. Am J Physiol. 1993;264: (Heart Circ Physiol.): H660-3.
    • (1993) Am J Physiol , vol.264
    • Hollenberg, S.M.1    Cunnion, R.E.2    Zimmerberg, J.3
  • 138
    • 0026346162 scopus 로고
    • Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock
    • Petros A, Bennett D, Vallance P. Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock. Lancet. 1991;338:1557-68.
    • (1991) Lancet , vol.338 , pp. 1557-1568
    • Petros, A.1    Bennett, D.2    Vallance, P.3
  • 140
    • 0026741759 scopus 로고
    • Overproduction of nitric oxide in cytokine-mediated and septic shock
    • Kilbourn RG, Griffith OW. Overproduction of nitric oxide in cytokine-mediated and septic shock. J Natl Cancer Inst. 1992;84:827-31.
    • (1992) J Natl Cancer Inst , vol.84 , pp. 827-831
    • Kilbourn, R.G.1    Griffith, O.W.2
  • 142
    • 0025158073 scopus 로고
    • Modulation of systemic blood pressure and renal haemodynamic responses by endothelium-derived relaxing factor (nitric oxide)
    • Moncada S, Higgs EA; eds. New York: Elsevier Science
    • Tolins JP, Raij L. Modulation of systemic blood pressure and renal haemodynamic responses by endothelium-derived relaxing factor (nitric oxide). In: Moncada S, Higgs EA; eds. Nitric Oxide from L-Arginine. New York: Elsevier Science; 1990:463-73.
    • (1990) Nitric Oxide from L-Arginine , pp. 463-473
    • Tolins, J.P.1    Raij, L.2
  • 143
    • 0025803673 scopus 로고
    • The involvement of endothelium-derived relaxing factor in the regulation of renal cortical blood flow in the rat
    • Walder CE, Thiemermann C, Vane JR. The involvement of endothelium-derived relaxing factor in the regulation of renal cortical blood flow in the rat. Br J Pharmacol. 1991;102:967-73.
    • (1991) Br J Pharmacol , vol.102 , pp. 967-973
    • Walder, C.E.1    Thiemermann, C.2    Vane, J.R.3
  • 144
    • 0025258432 scopus 로고
    • Role of nitric oxide in maintaining vascular integrity in endotoxin-induced acute intestinal damage in the rat
    • Hutcheson IR, Whittle BR, Boughton-Smith NK. Role of nitric oxide in maintaining vascular integrity in endotoxin-induced acute intestinal damage in the rat. Br J Pharmacol. 1990;101:815-20.
    • (1990) Br J Pharmacol , vol.101 , pp. 815-820
    • Hutcheson, I.R.1    Whittle, B.R.2    Boughton-Smith, N.K.3
  • 148
    • 0026729192 scopus 로고
    • Reversal of hyperdynamic response to continuous endotoxin administration by inhibition of NO synthesis
    • Meyer J, Traber LD, Nelson S, Lentz CW, Nakazawa H, Herndon DN, et al. Reversal of hyperdynamic response to continuous endotoxin administration by inhibition of NO synthesis. J Appl Physiol. 1992;73:324-8.
    • (1992) J Appl Physiol , vol.73 , pp. 324-328
    • Meyer, J.1    Traber, L.D.2    Nelson, S.3    Lentz, C.W.4    Nakazawa, H.5    Herndon, D.N.6
  • 151
    • 0028118814 scopus 로고
    • The third component of complement protects against Escherichia coli endotoxin-induced shock and multiple organ failure
    • Quezado ZM, Hoffman WD, Winkelstein JA, Yatsiv I, Koev CA, Cork LC, et al. The third component of complement protects against Escherichia coli endotoxin-induced shock and multiple organ failure. J Exp Med. 1994;179:569-78.
    • (1994) J Exp Med , vol.179 , pp. 569-578
    • Quezado, Z.M.1    Hoffman, W.D.2    Winkelstein, J.A.3    Yatsiv, I.4    Koev, C.A.5    Cork, L.C.6


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