Polypeptide extract from scorpion venom inhibits angiogenesis and angiogenesis-dependent tumor growth

Chinese Pharmacological Bulletin

Volumn 21, Issue 6, 2005, Pages 708-711

  Zhang, Wei Dong ^a   Cui, Ya Zhou ^b   Yao, Cheng Fang ^a   Jia, Qing ^a   Song, Sou Qin ^a   Wang, Zhao Xia ^a   Dong, Qiang ^a  

^a SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG FIRST MEDICAL UNIVERSITY   (China)

^b Shandong Medicinal Biotechnology Center   (China)

Author keywords

Angiogenesis; Chorioallantoic membrane assay; Hepacelluar carcinoma; Sarcoma; Scorpion venom

Indexed keywords

ANGIOGENESIS INHIBITOR; POLYPEPTIDE; SCORPION VENOM;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CHORIOALLANTOIS; DRUG EFFECT; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GROWTH INHIBITION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LIVER CELL CARCINOMA; NEOVASCULARIZATION (PATHOLOGY); SARCOMA; TUMOR GROWTH;

EID: 23444445047     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Lu N, Wang H, Yan JJ et al. Effect of component III in scorpion venom crude extracted from buthus martenssi karsch on the human jugular squamous cell carcinoma AGZY-973 cell line [J]. Clin J Clini Pharmacol Ther, 2002, 6(7): 515-7.
2. Wei L, Dong WH, Kong TH. Effect of antineoplastic polypeptide from buthus martenssi venom on human tumor cell lines and animal transplanting tumors [J]. Chin Onco, 2002, 12(2): 97-101.
3. Ribatti D, De-Falco G, Nico B et al. In vivo time-course of the angiogenic response induced by multiple myeloma plasma cells in the chick embryo chorioallantoic membrane [J]. J Anat, 2003, 203 (3): 323-8.
4. Muehlbauer PM. Anti-angiogenesis in cancer therapy [J]. Semin Oncol Nurs, 2003, 19(3): 180-92.
5. Bai X, Cerimele F, Ushio-Fukai M et al. Honokiol a small molecular weight natural product, inhibits angiogenesis in vitro and tumor growth in vivo [J]. J Biol Chem, 2003, 278(37): 35501-7.