Reverse transcriptase-like activity in Trypanosoma cruzi

Acta Tropica

Volumn 63, Issue 2-3, 1997, Pages 117-126

  Gonzalez C I ^a   Thomas, M C ^a   Martin F ^a   Alcami, J ^b   Alonso, C ^c   Lopez M C ^a  

^a INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

^b HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

^c CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

Author keywords

RNA dependent polymerase; RNA homopolymers; RT like inhibitors; Trypanosoma cruzi

Indexed keywords

DACTINOMYCIN; NOROBIOCIN; RIFAMPICIN; RNA DIRECTED DNA POLYMERASE; UNCLASSIFIED DRUG; ZIDOVUDINE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; NONHUMAN; TRYPANOSOMA CRUZI;

ANIMALS; APHIDICOLIN; CELL NUCLEUS; CYTOPLASM; DACTINOMYCIN; ENZYME INHIBITORS; MAGNESIUM; NUCLEIC ACID SYNTHESIS INHIBITORS; POLY A; POLY C; POLY G; POLY T; REVERSE TRANSCRIPTASE INHIBITORS; RIFAMYCINS; RNA, PROTOZOAN; RNA-DIRECTED DNA POLYMERASE; THYMINE NUCLEOTIDES; TRANSCRIPTION, GENETIC; TRYPANOSOMA; ZIDOVUDINE;

EID: 2342668452     PISSN: 0001706X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0001-706X(96)00611-0     Document Type: Article

References (21)

1. Bradford, M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
2. Brown, T.A., Ikemura, T., McClelland, M. and Roberts, R.J. (1991) DNA and RNA modifying enzymes. In Molecular Biology (Brown, T.A. ed), Vol. 5, Bios Scientific, Oxford, UK, pp. 139-191.
3. Carstens, J.M., Tracy, S., Chapman, N.M. and Gauntt, C.J. (1992) Detection of enteroviruses in cell culture by using in situ transcription. J. Clin. Microbiol. 30: 1, 25-35.
4. Deragon, J.M., Sinnett, D. and Labuda, D. (1990) Reverse transcriptase activity from human embryonal carcinoma cells NTera2D1. EMBO J. 9: 10, 3363-3368.
5. Doolittle, R.F., Feng, D.F., Johnson, M.S. and McClure, M.A. (1989) Origins and evolutionary relationships of retroviruses. Q. Rev. Biol. 64, 1-30.
6. Gabriel, A. and Boeke, J.D. (1991) Reverse transcriptase encoded by a retrotransposon from the trypanosomatid Crithidia fasciculata. Proc. Natl. Acad. Sci. 88, 9794-9798.
7. Ikegami, S., Taguchi, T., Ohashi, M., Oguro, M., Nagano, H. and Mano, Y. (1978) Aphidicolin prevents mitotic cell division by interfering with the activity of DNA polymerase-α. Nature 275, 458-460.
8. Ivanov, V.A., Melnikov, A.A., Siunov, A.V., Fodor, I.I. and Ilyin, Y. (1991) Authentic reverse transcriptase is coded by jockey, a mobile Drosophila element related to mammalian LINEs. EMBO J. 10, 1489-2495.
9. Kacian, D.L. (1977) Methods for assaying Reverse-Transcriptase. In Methods in Virology (Maramarosh, K. ed) Vol. 6, Columbia University College Physiology and Surgery, Institute of Cancer Research, New York, USA, pp. 143-184.
10. Kimmel, B.E., Onesmo, K., Ole, M. and Young, J.R. (1987) Ingi, a 5.2-kb dispersed sequence element from Trypanosoma brucei that carries half of a smaller mobile element at either end and has homology with mammalian LINEs. Mol. Cell. Biol. 7, 1465-1475.
11. Krokan, H., Schaffer, P. and DePamphilis, M.L. (1979) Involvement of eucaryotic deoxyribonucleic acid polymerases α and γ in the replication of cellular and viral deoxyribonucleic acid. Biochemistry 18, 4431-4443.
12. Martín, F; Requena, J.M, Martín, J., Alonso, C. and López, M.C. (1993) Cytoplasmic nuclear translocation of the Hsp70 protein during enviromental stress in Trypanosoma cruzi. BBRC 196: 3, 1155-1162.
13. Martín, F., Marañón, C., Olivares, M., Alonso, C. and López, M.C. (1995) Characterization of a Non-long terminal repeat retrotransposon cDNA (L1Tc) from Trypanosoma cruzi: Homology of the first ORF with the Ape family of DNA repair enzymes. J. Mol. Biol. 247, 49-59.
14. Maslov, D.A., Avila, H.A., Lake, J.A. and Simpson, L. (1994) Evolution of RNA editing in kinetoplastid protozoa. Nature 368, 345-348.
15. Mellor, J., Malim, M.H., Gull, K., Tuite, M.F., McCready, S.M., Dibbayawan, T., Kingsman, S.M. and Kingsman, A.J. (1985) Reverse transcriptase activity and TyRNA are associated with virus-like particles in yeast. Nature 318, 583-589.
16. Murphy, N.B., Pays, A., Tebabi, P., Coquelet, H., Guyaux, M., Steinert, M. and Pays, E. (1987) Trypanosoma brucei repeated element with unusual structural and transcriptional properties. J. Mol. Biol. 195, 855-871.
17. + transcript. Gene 146, 245-250.
18. Roth, M.J., Tanese, N. and Goff, S.P. (1985) Purification and characterization of murine retroviral reverse transcriptase expressed in Escherichia coli. J. Biol. Chem. 260, 9326-9335.
19. Shepherd, D. and Garland, P.B. (1973) Citrate synthase from rat liver. Methods Enzymol. 13, 11-16.
20. Simpson, L. and Maslov, D.A. (1994) RNA Editing and the evolution of parasites. Science 264, 1870-1871.
21. Xiong, Y. and Eickbush, T.H. (1990) Origin and evolution of retroelement based upon their reverse transcriptase sequence. EMBO J. 9, 3353-3362.