Long-term, but not short-term, treatment with somatotropin during pregnancy in underfed pigs increases the body size of progeny at birth

Journal of Animal Science

Volumn 82, Issue 1, 2004, Pages 93-101

  Gatford, K L ^a,c   Boyce, J M ^b,d   Blackmore, K ^a   Smits, R J ^b   Campbell, R G ^b,e   Owens, P C ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b QAF Meat Industries   (Australia)

^c Sch of Molec and Biomed Science   (Australia)

^d Tamworth Centre for Crop Improvement   (Australia)

^e Ausgene   (United States)

Author keywords

Birth Weight; Dietary Protein; Pig; Pregnancy; Somatotropin

Indexed keywords

PIERIS BRASSICAE; SUIDAE; SUS SCROFA;

EID: 2342653484     PISSN: 00218812     EISSN: None     Source Type: Journal    
DOI: 10.2527/2004.82193x     Document Type: Article

References (35)

1. Dourmad, J. Y. 1991. Effect of feeding level in the gilt during pregnancy on voluntary feed intake during lactation and changes in body composition during gestation and lactation. Livest. Prod. Sci. 27:309-319.
2. Dwyer, C. M., N. C. Stickland, and J. M. Fletcher. 1994. The influence of maternal nutrition on muscle fiber number development in the porcine fetus and on subsequent postnatal growth. J. Anim. Sci. 72:911-917.
3. Etienne, M., M. Bonneau, G. Kann, and F. Deletang. 1992. Effects of administration of growth hormone-releasing factor to sows during late gestation on growth hormone secretion, reproductive traits, and performance of progeny from birth to 100 kilograms live weight. J. Anim. Sci. 70:2212-2220.
4. Farmer, C., and P. Gaudreau. 1997. Presence of a bioactive and immunoreactive growth-hormone-releasing-factor-like substance in porcine placenta. Biol. Neonate 72:363-369.
5. Farmer, C., M. F. Palin, and M. T. Sorensen. 2000. Mammary gland development and hormone levels in pregnant Upton-Meishan and Large White gilts. Domest. Anim. Endocrinol. 18:241-251.
6. Fholenhag, K. I., I. M. Sandstrom, K. Malmlof, A. I. Skottner, and F. J. Nyberg. 1994. Human growth hormone does not cross the placenta of the pregnant rat. Growth Regul. 4:181-187.
7. Gatford, K. L., J. E. Ekert, K. Blackmore, M. J. De Blasio, J. M. Boyce, J. A. Owens, R. G. Campbell, and P. C. Owens. 2003. Variable maternal nutrition and growth hormone treatment in the second quarter of pregnancy in pigs alter semitendinosus muscle in adolescent progeny. Br. J. Nutr. 90:283-293.
8. Gatford, K. L., J. A. Owens, R. G. Campbell, J. M. Boyce, P. A. Grant, M. J. De Blasio, and P. C. Owens. 2000. Treatment of underfed pigs with GH throughout the second quarter of pregnancy increases fetal growth. J. Endocrinol. 166:227-234.
9. Harding, J. E., P. C. Evans, and P. D. Gluckman. 1997. Maternal growth hormone treatment increases placental diffusion capacity but not fetal or placental growth in sheep. Endocrinology 138:5352-5358.
10. Kelley, R. L., S. B. Jungst, T. E. Spencer, W. F. Owsley, C. H. Rahe, and D. R. Mulvaney. 1995. Maternal treatment with growth hormone alters embryonic development and early postnatal growth of pigs. Domest. Anim. Endocrinol. 12:83-94.
11. Kelly, P. A., T. Tsushima, R. P. C. Shiu, and H. G. Friesen. 1976. Lactogenic and growth hormone-like activities in pregnancy determined by radioreceptor assays. Endocrinology 99:765-774.
12. Kveragas, C. L., R. W. Seerley, R. J. Martin, and W. L. Vandergrift. 1986. Influence of exogenous growth hormone and gestational diet on sow blood and milk characteristics and on baby pig blood, body composition and performance. J. Anim. Sci. 63:1877-1887.
13. Lacroix, M. C., J. Guibourdenche, J. L. Frendo, F. Muller, and D. Evain-Brion. 2002. Human placental growth hormone - A review. Placenta 16:S87-S94.
14. Magri, K. A., A. M. Adamo, D. LeRoith, and T. D. Etherton. 1990. The inhibition of insulin action and glucose metabolism by porcine growth hormone in porcine adipocytes is not the result of any decrease in insulin binding or insulin receptor kinase activity. Biochem. J. 266:107-113.
15. McIntyre, H. D., R. Serek, D. I. Crane, T. Veveris-Lowe, A. Parry, S. Johnson, K. C. Leung, K. K. Y. Ho, M. Bougoussa, G. Hennen, A. Igout, F.-Y. Chan, D. Cowley, A. Cotterill, and R. Barnard. 2000. Placental growth hormone (GH), GH-binding protein, and insulin-like growth factor axis in normal, growth-retarded, and diabetic pregnancies: Correlations with fetal growth. J. Clin. Endocrinol. Metab. 85:1143-1150.
16. Mirlesse, V., F. Frankenne, E. Alsat, M. Poncelet, G. Hennen, and D. Evain-Brion. 1993. Placental growth hormone levels in normal pregnancy and in pregnancies with intrauterine growth retardation. Pediatr. Res. 34:439-442.
17. Mullan, B. P., and I. H. Williams. 1989. The effect of body reserves at farrowing on the reproductive performance of first-litter sows. Anim. Prod. 48:449-457.
18. National Health and Medical Research Council of Australia. 1997. Australian code of practice for the care and use of animals for scientific purposes. Australian Gov. Pub. Serv., Canberra.
19. National Research Council (U.S.) Subcommittee on Swine Nutrition. 1998. Nutrient requirements of swine. National Academy Press. Washington, DC.
20. Noblet, J., W. H. Close, R. P. Heavens, and D. Brown. 1985. Studies on the energy metabolism of the pregnant sow. 1. Uterus and mammary tissue development. Br. J. Nutr. 53:251-265.
21. Pettigrew, J. E. 1993. Amino acid nutrition of gestating and lactating sows. Nutri-Quest, Inc., St. Louis, MO.
22. Pond, W. G., R. R. Maurer, H. J. Mersmann, and S. Cummins. 1992. Response of fetal and newborn piglets to maternal protein restriction during early or late pregnancy. Growth Dev. Aging 56:115-127.
23. Rehfeldt, C., I. Fiedler, R. Weikard, E. Kanitz, and K. Ender. 1993. It is possible to increase skeletal muscle fibre number in utero. Biosci. Rep. 13:213-220.
24. Rehfeldt, C., G. Kuhn, G. Nürnberg, E. Kanitz, F. Schneider, M. Beyer, K. Nürnberg, and K. Ender. 2001. Effects of exogenous somatotropin during early gestation on maternal performance, fetal growth, and compositional traits in pigs. J. Anim. Sci. 79:1789-1799.
25. Revell, D. K., I. H. Williams, B. P. Mullan, J. L. Ranford, and R. J. Smits. 1998. Body composition at farrowing and nutrition during lactation affect the performance of primiparous sows: I. Voluntary feed intake, weight loss, and plasma metabolites. J. Anim. Sci. 76:1729-1737.
26. Schneider, F., E. Kanitz, D. E. Gerrard, G. Kuhn, K. P. Brüssow, K. Nürnberg, I. Fiedler, G. Nürnberg, K. Ender, and C. Rehfeldt. 2002. Administration of recombinant porcine somatotropin (rpST) changes hormone and metabolic status during early pregnancy. Domest. Anim. Endocrinol. 23:455-474.
27. Schoknecht, P. A., W. G. Pond, H. J. Mersmann, and R. R. Maurer. 1993. Protein restriction during pregnancy affects postnatal growth in swine progeny. J. Nutr. 123:1818-1825.
28. Sinha, Y. N., H. G. Klemke, R. R. Maurer, and B. P. Jacobsen. 1990. Changes in the glycosylated and nonglycosylated forms of prolactin and growth hormone in lean and obese pigs during pregnancy. Endocrinology 127:410-418.
29. Southard, J., and F. Talamantes. 1991. Placental prolactin-like proteins in rodents: Variations on a structural theme. Mol. Cell. Endocrinol. 79:C133-C140.
30. Sterle, J. A., T. C. Cantley, W. B. Lamberson, M. C. Lucy, D. E. Gerrard, R. L. Matteri, and B. N. Day. 1995. Effects of recombinant porcine growth hormone on placental size, fetal growth, and IGF-I and IGF-II concentrations in pigs. J. Anim. Sci. 73:2980-2985.
31. Sterle, J. A., T. C. Cantley, R. L. Matteri, J. A. Carroll, M. C. Lucy, and W. R. Lamberson. 2003. Effect of recombinant porcine somatotropin on fetal and placental growth in gilts with reduced uterine capacity. J. Anim. Sci. 81:765-771.
32. Walker, W., S. Fitzpatrick, H. Barrera-Saldana, D. Resendez-Perez, and G. Saunders. 1991. The human placental lactogen genes: Structure, function, evolution and transcriptional regulation. Endocr. Rev. 12:316-328.
33. Wallis, M. 1996. The molecular evolution of vertebrate growth hormones: A pattern of near-stasis interrupted by sustained bursts of rapid change. J. Mol. Evol. 43:93-100.
34. Walton, P. E., and T. D. Etherton. 1986. Stimulation of lipogenesis by insulin in swine adipose tissue: Antagonism by porcine growth hormone. J. Anim. Sci. 62:1584-1595.
35. Zar, J. H. 1974. Comparing simple linear regression equations. Pages 228-235 in Biostatistical analysis. Prentice-Hall, Englewood Cliffs, N.J.