Evaluation of series of isobenzofuranone dimers as PKCα ligands: Implication for the distance between the two ligand binding sites

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 11, 2004, Pages 2969-2972

  Baba, Yoshiyasu ^a,b   Mayumi, Satoshi ^c   Hirai, Go ^a   Kawasaki, Hidekazu ^a   Ogoshi, Yosuke ^a   Yanagisawa, Takeshi ^b   Hashimoto, Yuichi ^c   Sodeoka, Mikiko ^a,b,c,d  

^a TOHOKU UNIVERSITY   (Japan)

^b SAGAMI CHEMICAL RESEARCH CENTER   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOFURAN DERIVATIVE; FURANONE DERIVATIVE; ISOBENZOFURAN DERIVATIVE; ISOBENZOFURANONE; PROTEIN KINASE C; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; COVALENT BOND; DRUG BINDING SITE; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; LIGAND BINDING; PROTEIN FAMILY; SIGNAL TRANSDUCTION;

BENZOFURANS; BINDING SITES; DIMERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; ENZYME INHIBITORS; HUMANS; LIGANDS; PROTEIN BINDING; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 2342643572     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.02.098     Document Type: Article

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