Stabilization of pyoderma gangrenosum ulcer with oral cyclosporine prior to skin grafting

Plastic and Reconstructive Surgery

Volumn 113, Issue 5, 2004, Pages 1417-1420

  Zakhireh, Mohammed ^a,b   Rockwell, W Bradford ^a,b   Fryer, Richard H ^a,b  

^a Univ of Utah Health Sciences Center ^*  (United States)

^b UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOYL PEROXIDE; CYCLOSPORIN; IMMUNOMODULATING AGENT; LYMECYCLINE; PSEUDOMONIC ACID;

ADULT; ARTICLE; AUTOIMMUNE DISEASE; BEHCET DISEASE; CASE REPORT; CHRONIC DISEASE; CROHN DISEASE; DYSPROTEINEMIA; FEMALE; HELPER CELL; HUMAN; IMMUNOMODULATION; INFECTION COMPLICATION; PRIORITY JOURNAL; PUSTULE; PYODERMA GANGRENOSUM; RHEUMATOID ARTHRITIS; SKIN GRAFT; SKIN NODULE; SKIN ULCER; SPLIT THICKNESS SKIN GRAFT; SUPPRESSOR CELL; SYMPTOMATOLOGY; ULCERATIVE COLITIS; MIDDLE AGED; PREOPERATIVE CARE; SKIN TRANSPLANTATION;

ADULT; CYCLOSPORINE; FEMALE; HUMANS; MIDDLE AGED; PREOPERATIVE CARE; PYODERMA GANGRENOSUM; SKIN TRANSPLANTATION;

EID: 2342639549     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.PRS.0000112762.22427.C4     Document Type: Article

References (15)

1. Fitzpatrick, T. B., Suurmond, D., Wolff, K., and Johnson, R. A. (Eds.). Color Atlas and Synopsis of Clinical Dermatology, 2nd Ed. New York: McGraw Hill, 1992. Pp. 532-535.
2. Ryan, T. J. Cutaneous vasculitis. In R. H. Champion, J. L. Burton, and F. J. Ebling (Eds.), Textbook of Dermatology, Vol. 3, 5th Ed. Oxford, United Kingdom: Blackwell Scientific Publications, 1991.
3. Hughes, J. R., Smith, E., Higgins, E. M., et al. Pyoderma gangrenosum in a patient with RA responding to treatment with cyclosporine-A. Br. J. Rheumatol. 33: 680, 1994.
4. Shelley, E. D., and Shelley, W. B. Cyclosporine therapy for pyoderma gangrenosum associated with sclerosing cholangitis and ulcerative colitis. J. Am. Acad. Dermatol. 18: 1084, 1988.
5. Magid, M. L., and Gold, M.H. Treatment of recalcitrant pyoderma gangrenosum with cyclosporine. J. Am. Acad. Dermatol. 20: 293, 1989.
6. Elgart, G., Stover, P., Larson, K., et al. Treatment of pyoderma gangrenosum with cyclosporine: Results in seven patients. J. Am. Acad. Dermatol. 24: 83, 1991.
7. Long, P. I., and Uesu, C. T. Pyoderma gangrenosum. J.A.M.A. 187: 100, 1964.
8. Wustrack, K. O., and Zarem, H. A. Pyoderma gangrenosum: Recognition and management. Plast. Reconstr. Surg. 62: 423, 1978.
9. Davis, J. C., Landeen, J. M., and Levine, R. A. Pyoderma gangrenosum: Skin grafting after preparation with hyperbaric oxygen. Plast. Reconstr. Surg. 79: 200, 1987.
10. Vereecken, P., Wautrecht, J. C., DeDobbeleer, G., et al. A case of pyoderma gangrenosum stabilized with lymecycline, topical benzoyl peroxide and treated by autograft. Dermatology 195: 50, 1997.
11. Limova, M., and Mauro, T. Treatment of leg ulcers with cultured epithelial autografts: Clinical study and case reports. Ostomy/Wound Manage. 48: 60, 1995.
12. Cyclosporine: Product information. In Physicians' Desk Reference. Montvale, NJ.: Medical Economics, 1998. Pp. 1882-1889.
13. Phillips, T. J., Kehinde, O., Green, H., et al. Treatment of skin ulcers with cultured epidermal allografts. J. Am. Acad. Dermatol. 21: 191, 1989.
14. Phillips, T. J., Bhawan, J., Leigh, I. M., et al. Cultured epidermal autografts and allografts: A study in differentiation and survival. J. Am. Acad. Dermatol. 23: 189, 1990.
15. Oliver, A. M., Kaawach, W., Mithoff, E. W., et al. The differentiation and proliferation of newly formed epidermis on wounds treated with cultured epithelial allografts. Br. J. Dermatol. 125: 147, 1991.