A prospective cohort study of retinal arteriolar narrowing and mortality

American Journal of Epidemiology

Volumn 159, Issue 9, 2004, Pages 819-825

  Wong, Tien Yin ^a,b   Knudtson, Michael D ^c   Klein, Ronald ^c   Klein, Barbara E K ^c   Hubbard, Larry D ^c  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Arterioles; Cardiovascular diseases; Hypertension; Mortality; Retina; Venules

Indexed keywords

CARDIOVASCULAR DISEASE;

ADULT; AGE; AGED; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CAUSE OF DEATH; COHORT ANALYSIS; COMPUTER ASSISTED DIAGNOSIS; DIABETES MELLITUS; DISEASE ASSOCIATION; EYE PHOTOGRAPHY; FEMALE; GENDER; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; MORTALITY; NONBIOLOGICAL MODEL; POPULATION RESEARCH; PROSPECTIVE STUDY; RETINA ARTERY OCCLUSION; UNITED STATES; AGE DISTRIBUTION; ARTERIOLE; HEALTH SURVEY; MIDDLE AGED; MULTIVARIATE ANALYSIS; PATHOLOGY; PHOTOGRAPHY; PROPORTIONAL HAZARDS MODEL; RETINA ARTERY; RISK FACTOR; SEX RATIO; SIGNAL PROCESSING; STENOSIS, OCCLUSION AND OBSTRUCTION; SURVIVAL;

ADULT; AGE DISTRIBUTION; AGED; ARTERIOLES; CARDIOVASCULAR DISEASES; CAUSE OF DEATH; CONSTRICTION, PATHOLOGIC; FEMALE; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PHOTOGRAPHY; POPULATION SURVEILLANCE; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RETINAL ARTERY; RETINAL ARTERY OCCLUSION; RISK FACTORS; SEX DISTRIBUTION; SIGNAL PROCESSING, COMPUTER-ASSISTED; SURVIVAL ANALYSIS; WISCONSIN;

EID: 2342625396     PISSN: 00029262     EISSN: None     Source Type: Journal    
DOI: 10.1093/aje/kwh119     Document Type: Article

References (31)

1. Wong TY, Klein R, Klein BEK, et al. Retinal microvascular abnormalities and their relations with hypertension, cardiovascular diseases and mortality. Surv Ophthalmol 2001;46:59-80.
2. Breslin DJ, Gifford RW Jr, Fairbairn JF II, et al. Prognostic importance of ophthalmoscopic findings in essential hypertension. JAMA 1966;195:335-8.
3. Svardsudd K, Wedel H, Aurell E, et al. Hypertensive eye ground changes: prevalence, relation to blood pressure and prognostic importance. Acta Med Scand 1978;204:159-67.
4. Gillum RF. Retinal arteriolar findings and coronary heart disease. Am Heart J 1991;122:262-3.
5. Dimmitt SB, West JN, Eames SM, et al. Usefulness of ophthalmoscopy in mild to moderate hypertension. Lancet 1989;1: 1103-6.
6. Hubbard LD, Brothers RJ, King WN, et al. Methods for evaluation of retinal microvascular abnormalities associated with hypertension/sclerosis in the Atherosclerosis Risk in Communities Study. Ophthalmology 1999;106:2269-80.
7. Sharrett AR, Hubbard LD, Cooper LS, et al. Retinal arteriolar diameters and elevated blood pressure: The Atherosclerosis Risk in Communities Study. Am J Epidemiol 1999;150:263-70.
8. Wong TY, Klein R, Couper DJ, et al. Retinal microvascular abnormalities and incident strokes. The Atherosclerosis Risk in Communities Study. Lancet 2001;358:1134-40.
9. Wong TY, Klein R, Sharrett AR, et al. Retinal arteriolar narrowing and risk of diabetes in middle-aged persons. JAMA 2002;287:2528-33.
10. Wong TY, Klein R, Sharrett AR, et al. Retinal arteriolar narrowing and incident coronary heart disease in men and women: the Atherosclerosis Risk in Communities Study. JAMA 2002; 287:1153-9.
11. Wong TY, Hubbard LD, Klein R, et al. Retinal microvascular abnormalities and blood pressure in older people: The Cardiovascular Health Study. Br J Ophthalmol 2002;86:1007-13.
12. Wong TY, Klein R, Nieto FJ, et al. Retinal microvascular abnormalities and ten-year cardiovascular mortality. A population-based case-control study. Ophthalmology 2003;110:933-40.
13. Klein R, Klein BEK, Linton KLP, et al. The Beaver Dam Eye Study: visual acuity. Ophthalmology 1991;98:1310-15.
14. Wong TY, Klein R, Klein BEK, et al. Retinal vessel diameters and their associations with age and blood pressure. Invest Ophthalmol Vis Sci 2003;44:4644-50.
15. Knudtson MD, Lee KE, Hubbard LD, et al. A revised method for summarizing retinal vessel diameters. Curr Eye Res 2003; 27:143-9.
16. Klein R, Klein BEK, Moss SE. Age-related eye disease and survival. The Beaver Dam Eye Study. Arch Ophthalmol 1995;113: 333-9.
17. Klein R, Klein BEK. Beaver Dam Eye Study: manual of operations. Springfield, VA: US Department of Commerce, 1991. (National Technical Information Service accession no. PB 91149823).
18. The hypertension detection and follow-up program: Hypertension Detection and Follow-up Program Cooperative Group. Prev Med 1976;5:207-15.
19. Cruickshank JM, Thorp JM, Zacharias FJ. Benefits and potential harm of lowering blood pressure. Lancet 1987;1:581-4.
20. Stewart I. Relation of reduction in pressure to first myocardial infarction in patients receiving treatment for severe hypertension. Lancet 1979;1:861-5.
21. Samuelsson DG, Wilhemsen LW, Pennart K, et al. The J-shaped relationship between coronary heart disease and achieved blood pressure in treated hypertensions: further analyses of 12 years of follow-up of treated hypertensive patients in the Primary Prevention Trial in Gothenburg, Sweden. J Hypertens 1990;8:547-55.
22. Alderman MH, Ooi WL, Madhaven S, et al. Treatment-induced blood pressure: reductions and risk of myocardial infarction. JAMA 1989;262:920-4.
23. Langer RO, Ganiats TG, Barrett-Connor E. Paradoxical survival with higher blood pressures in older men. BMJ 1989;298: 1356-7.
24. Boutitie F, Gueyffier F, Pocock S, et al. J-shaped relationship between blood pressure and mortality in hypertensive patients: new insights from a meta-analysis of individual-patient data. Ann Intern Med 2002;136:438-48.
25. Farnett L, Mulrow CD, Linn WD, et al. The J-curve phenomenon and the treatment of hypertension. JAMA 1991;265:489-95.
26. D'Agostino RB, Belanger AJ, Kannel WB, et al. Relation of low diastolic blood pressure to coronary heart disease death in presence of myocardial infarction: the Framingham Study. BMJ 1991;303:385-9.
27. Klein R, Sharrett AR, Klein BEK, et al. Are retinal arteriolar abnormalities related to atherosclerosis? The Atherosclerosis Risk in Communities Study. Arterioscler Thromb Vasc Biol 2000;20:1644-50.
28. Cruickshank JM. Coronary flow reserve and the J-curve relation between diastolic blood pressure and myocardial infarction. BMJ 1988;297:1227-30.
29. Leishman R. The eye in general vascular diseases: hypertension and arteriosclerosis. Br J Ophthalmol 1957;41:641-701.
30. Folsom AR, Gomez-Marin O, Gillum RF, et al. Out-of-hospital coronary death in an urban population-validation of death certificate diagnosis: The Minnesota Heart Survey. Am J Epidemiol 1987;125:1012-18.
31. Knudtson MD, Klein BEK, Klein R, et al. Variation associated with measurement of retinal vessel diameters at different points in the pulse cycle. Br J Ophthalmol 2004;88:57-61.