Two regimens of azithromycin prophylaxis against community-acquired respiratory and skill/soft-tissue infections among military trainees

Clinical Infectious Diseases

Volumn 38, Issue 8, 2004, Pages 1095-1101

  Guchev, Igor A ^a   Gray, Gregory C ^c   Klochkov, Oleg I ^b  

^a Respiratory Disease Unit   (Russian Federation)

^b Med Force of Moscow Military Region   (Russian Federation)

^c UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; AZITHROMYCIN; CEFOTAXIME; CLARITHROMYCIN; CLINDAMYCIN; COTRIMOXAZOLE; ERYTHROMYCIN; MIOKAMYCIN; PENICILLIN G; TETRACYCLINE; ANTIINFECTIVE AGENT;

ADOLESCENT; ADULT; ARMY; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EVALUATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MORBIDITY; PRIORITY JOURNAL; PROPHYLAXIS; RESPIRATORY TRACT INFECTION; SCHOOL CHILD; SOFT TISSUE INFECTION; STREPTOCOCCUS PNEUMONIAE; ANTIBIOTIC PROPHYLAXIS; COMMUNICABLE DISEASE; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; SOLDIER;

ADULT; ANTI-BACTERIAL AGENTS; ANTIBIOTIC PROPHYLAXIS; AZITHROMYCIN; COMMUNITY-ACQUIRED INFECTIONS; HUMANS; MALE; MILITARY PERSONNEL; PROSPECTIVE STUDIES; RESPIRATORY TRACT INFECTIONS; RISK FACTORS; SOFT TISSUE INFECTIONS;

EID: 2342620898     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/382879     Document Type: Article

References (21)

1. Craig S, Kolavic S, Hastings D, et al. Outbreak of pneumococcal pneumonia among Ranger students, Fort Benning, Georgia Medical Surveillance Monthly Report 1999; 5:2, 3, 8.
2. Gray GC. Acute respiratory disease in the military. Fed Pract 1995; 12:27-33.
3. Ryan MA, Christian RS, Wohlrabe J. Handwashing and respiratory illness among young adults in military training. Am J Prev Med 2001; 21:79-83.
4. Gray GC, Witucki PJ, Gould MT, et al. Randomized, placebo controlled clinical trial of oral azithromycin prophylactics against respiratory infections in a high-risk, young adult population. Clin Infect Dis 2001; 33: 983-9.
5. Amundson DE, Weiss PJ. Pneumonia in military recruits. Mil Med 1994; 159:629-31.
6. Ekman MR, Grayston JT, Visakorpy R, Kleemola M, Kuo CC, Saikku P. An epidemic of infections due to Chlamydia pneumoniae in military conscripts. Clin Infect Dis 1993; 17:420-5.
7. Gray GC, Mitchell BS, Tueller JE, Cross ER, Amundson DE. Pneumonia hospitalizations in the US Navy and Marine Corps: rates and risk factors for 6522 admissions, 1981-1991. Am J Epidemiol 1994; 139: 793-802.
8. Mohamed AR, Evans DA. The spectrum of pneumonia in 1983 at the Riyadh Armed Forces Hospital. J Infect 1987; 14:31-7.
9. Fujikawa J, Struewing JP, Hyams KC, Kaplan EL, Tupponce AK, Gray GC. Oral erythromycin prophylaxis against Streptococcus pyogenes infections in penicillin-allergic military recruits: a randomized clinical trial. J Infect Dis 1992; 166:162-5.
10. Gray GC, McPhate DC, Leinonen M, et al. Weekly oral azithromycin as prophylaxis for agents causing acute respiratory disease. Clin Infect Dis 1998; 26:103-10.
11. Thomas RJ, Conwill DE, Morton DE, Brooks TJ, Holmes CK, Mahaffey WB. Penicillin prophylaxis for streptococcal infections in United States Navy and Marine Corps recruit camps, 1951-1985. Rev Infect Dis 1988; 10:125-30.
12. Sanchez JL, Craig SC, Kolavic S, et al. An outbreak of pneumococcal pneumonia among military personnel at high risk: control by low-dose azithromycin postexposure chemoprophylaxis. Mil Med 2003; 168:1-6.
13. Normark HB, Kalin M, Örtqvist Å, et al. Dynamics of penicillin-susceptible clones in invasive pneumococcal disease. J Infect Dis 2001; 184:861-9.
14. NCCLS. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. M100-S12. MIC testing supplemental tables. Villanova, PA: NCCLS, 2002:110-2.
15. Klausner JD, Passaro D, Rosenberg J, et al. Enhanced control of an outbreak of Mycoplasma pneumoniae pneumonia with azithromycin prophylactics. J Infect Dis 1998; 177:161-6.
16. Leach AJ, Shelby-James TM, Mayo M, et al. A prospective study of the impact of community-based azithromycin treatment of trachoma on carriage and resistance of Streptococcus pneumoniae. Clin Infect Dis 1997; 24:356-62.
17. Morita JY, Kahn E, Thompson T, et al. Impact of azithromycin on oropharyngeal carriage of group A Streptococcus and nasopharyngeal carriage of macrolide-resistant Streptococcus pneumoniae. Pediatr Infect Dis J 2000; 19:41-6.
18. Fry AM, Jha HC, Lietman TM, et al. Adverse and beneficial secondary effects of mass treatment with azithromycin to eliminate blindness due to trachoma in Nepal. Clin Infect Dis 2002; 35:395-402.
19. Gaynor BD, Holbrook KA, Whitcher JP, et al. Community treatment with azithromycin for trachoma is not associated with antibiotic resistance in Streptococcus pneumoniae at 1 year. Br J Ophthalmol 2003; 87:147-8.
20. Matute AJ, Schurink CA, Krijnen RM, Florijn A, Rozenberg-Arska M, Hoepelman IM. Double-blind, placebo-controlled study comparing the effect of azithromycin with clarithromycin on oropharyngeal and bowel microflora in volunteers. Eur J Clin Microbiol Infect Dis 2002; 21: 427-31.
21. Putnam SD, Gray GC, Biedenbach DJ, Jones RN. Pharyngeal colonization prevalence rates for Streptococcus pyogenes and Streptococcus pneumoniae in a respiratory chemoprophylactics intervention study using azithromycin. Clin Microbiol Infect 2000; 6:2-8.