A Systematic Approach to Scale-Up the High-Shear Granulation Process for Mebendazole Tablets to Achieve a Scale-Independent Drug Release

Acta Pharmaceutica Turcica

Volumn 46, Issue 1, 2004, Pages 25-34

  Kalaiselvan, R ^a   Prasad, G S ^a   Madhusudhan, S ^a   Naik, P R ^b   Manavalan, R ^a  

^a ANNAMALAI UNIVERSITY   (India)

^b ZYDUS RESEARCH CENTRE   (India)

Author keywords

Drug release; Dynamic similarity; Echinococcosis; High shear granulation; Scale up; Tip velocity

Indexed keywords

CALCIUM CARBONATE; CARBOXYMETHYLCELLULOSE; CROSCARMELLOSE SODIUM; MAGNESIUM STEARATE; MEBENDAZOLE; POLYSORBATE 80; STARCH; STARCH GLYCOLATE SODIUM; TALC;

ARTICLE; BATCH PROCESS; DISSOLUTION; DRUG GRANULATION; DRUG MANUFACTURE; DRUG RELEASE; REPRODUCIBILITY; SHEAR STRESS; TABLET;

EID: 2342616651     PISSN: 1300638X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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