Telomerase activity and telomerase catalytic subunit in hepatocellular carcinoma

Hepato-Gastroenterology

Volumn 51, Issue 57, 2004, Pages 796-800

  Lee, Chuan Mo ^a   Hsu, Ching Yi ^b   Eng, Hock Liew ^a   Huang, Wu Siung ^a   Lu, Sheng Nan ^a   Changchien, Chi Sin ^a   Chen, Chao Long ^a   Cho, Chung Lung ^c  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE   (Taiwan)

^c NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

Diagnosis; Hepatocellular carcinoma; hTERT; Telomerase activity; Telomerase catalytic subunit

Indexed keywords

MESSENGER RNA; MOLECULAR MARKER; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE;

ADULT; AGED; ARTICLE; CANCER GRADING; CATALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN TISSUE; LIVER CELL CARCINOMA; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TELOMERIC REPEAT AMPLIFICATION PROTOCOL;

ADULT; AGED; CARCINOMA, HEPATOCELLULAR; CHILD, PRESCHOOL; DNA-BINDING PROTEINS; FEMALE; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; TELOMERASE;

EID: 2342599691     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Harley CB, Villeponteau B: Telomeres and telomerase in aging and cancer. Curr Opin Genet Dev 1995; 5:249-255.
2. Shay JW, Bacchetti S: A survey of telomerase activity in human cancer. Eur J Cancer 1997; 33:787-791.
3. Counter CM, Avilion AA, LeFeuvre CE, Stewart NG, Greider CW, Harley CB, Bacchetti S: Telomerase shortening associated witch chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J 1992; 11:1921-1929.
4. Chen HJ, Liang CL, Lu K, Lin JW, Cho CL: Implication of telomerase activity and alterations of telomere length in the histologic characteristics of intracranial meningiomas. Cancer 2000; 89:2092-2098.
5. Counter CM, Meyerson M, Eaton EN, Weinberg RA: The catalytic subunit of yeast telomerase. Proc Natl Acad Sci USA 1997; 94:9202-9207.
6. Takakura M, Kyo S, Kanaya T, Tanaka M, Inoue M: Expression of human telomrease subunits and correlation with telomerase activity in cervical cancer. Cancer Res 1998; 58:1558-1561.
7. Tono MJ, Sun SC, Schaeffer BT, Chano NK, Lo KJ, Petters RL: Hepatitis-associated antigen and hepatocellular carcinoma in Taiwan. Ann Intern Med 971; 75:687-691.
8. Chen DS, Kuo GC, Sung JL, Lai MY, Sheu JC, Chen PJ, Yang PM, Hsu HM, Chang MH, Chen CJ, et al: Hepatitis C virus infection in an area hyperendemic for hepatitis B and chronic liver disease: the Taiwan experience. J Infect Dis 1990; 162:817-822.
9. Ki NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PL, Coviello GM, Wright WE, Weinrich SL, Shay JW: Specific association of human telomerase activity with immortal cells and cancer. Science 1994; 266:2011-2015.
10. Hiyama E, Yokoyama T, Tatsumoto N, Hiyama K, Imamura Y, Murakami Y, Kodama T, Piatyszek MA, Shay JW, Matsuura Y: Telomerase activity in gastric cancer. Cancer Res 1995; 55:3258-3262.
11. Counter CM, Gupta J, Harley CB, Leber B, Bacchetti S: Telomerase activity in normal leukocytes and in hematologic malignancies. Blood 1995; 85:315-320.
12. Hiyama K, Hirai Y, Kyoizumi S, Akiyama M, Hiyama E, Piatyszek MA, Shay JW, Ishioka S, Yamakido M: Activation of telomerase in human lymphocytes and hematopoietic progenitor cells. J Immunol 1995; 155:3711-3715.
13. Harada K, Yasoshima M, Ozaki S, Sanzen T, Nakanuma Y: PCR and in situ hybridization studies of telomerase subunits in human non-neoplastic livers. J Pathol 2001; 193:210-217.
14. Hytiroglou P, Kotoula V, Thung SN, Tsokos M, Fiel MI, Papadimitriou CS: Telomerase activity in precancerous hepatic nodules. Cancer 1998; 82:1831-1838.
15. Nakayama J, Tahara H, Tahara E, Saito M, Ito K, Nakamura H, Nakanishi T, Tahara E, Ide T, Ishikawa F: Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinoma. Nat Genet 1998; 18:65-68.
16. Hisatomi H, Nagao K, Kanamaru T, Endo H, Tomimatsu M, Hikiji K: Levels of telomerase catalytic subunit mRNA as a predictor of potential malignancy. Int J Oncol 1999; 14:727-732.
17. Snow JH JR, Goldstein HM, Wallace S: Comparison of scintigraphy, sonography and computed tomography in the evaluation of hepatic neoplasm. Am J Roentgenol 1979; 132:915.
18. Kinami Y, Yokota H, Takata M, Takashima S, Yamamoto I: Magnetic resonance imaging in the diagnosis of tumors of the liver. Gastroenterol Jap 1988; 23:139-146.
19. Takayasu K, Moriyaman N, Muramutsu Y, Makuuchi M, Hasegawa H, Okazaki N, Hirohashi S: The diagnosis of small hepatocellular carcinomas: efficacy of various imaging procedures in 100 patients. Am J Roentgenol 1990; 155:49-54.
20. Ikeda K, Saltoh S, Koida I, Tsubota A, Arase Y, Chayama K, Kumada H: Diagnosis and follow-up of small hepatocellular carcinoma with selective intraarterial digital substraction angiography. Hepatology 1993; 17:1003-1007.
21. Okuda K, Kojiro M: Small hepatocellular carcinoma. In: Okuda K, Ishak KG (Eds.). Neoplasms of the liver. Tokyo: Springer, 1987; pp. 215-225.
22. Kondo F, Wada K, Nagato Y, Nakajima T, Kondo Y, Hirooka N, Ebara M, Ohto M, Okuda K: Biopsy diagnosis of well-differentiated hepatocellular carcinoma based on new morphologic criteria. Hepatology 1989; 9:751-755.