Validation of a GC-MS screening method for anabolizing agents in solid nutritional supplements

Biomedical Chromatography

Volumn 18, Issue 3, 2004, Pages 155-159

  Van Thuyne, W ^a   Delbeke, Frans T ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Doping; Metandienone; Nandrolone and prohormones; Stanozolol; Testosterone and prohormones

Indexed keywords

DIETHYL ETHERS; LIQUID-LIQUID EXTRACTION; METANDIENONE; NANDROLONE; NANDROLONE AND PROHORMONE; NUTRITIONAL SUPPLEMENTS; SCREENING METHODS; STANOZOLOL; TESTOSTERONE; TESTOSTERONE AND PROHORMONE;

SODIUM HYDROXIDE;

3BETA ANDROSTANEDIOL; AMMONIA; ANABOLIC AGENT; ANDROSTANEDIOL; ANDROSTANOLONE; ANDROSTENEDIONE; ANDROSTERONE; BOLDENONE; CLENBUTEROL; ESTR 4 ENE 3,17 DIONE; ETHER; HORMONE PRECURSOR; IODINE DERIVATIVE; LEVODOPA; METANDIENONE; METHYLTESTOSTERONE; NANDROLONE; NANDROLONE DECANOATE; NANDROLONE LAURATE; NANDROLONE PHENPROPIONATE; PENTANE; PRASTERONE; SODIUM HYDROXIDE; STANOZOLOL; TESTOSTERONE; TESTOSTERONE PHENYLPROPIONATE; TESTOSTERONE PROPIONATE; TESTOSTERONE UNDECANOATE; THIOL DERIVATIVE; UNINDEXED DRUG;

ARTICLE; CONTROLLED STUDY; DERIVATIZATION; DISTILLATION; DOPING; DRUG ISOLATION; DRUG SCREENING; GAS CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MASS SPECTROMETRY; SENSITIVITY AND SPECIFICITY; URINE; VALIDATION PROCESS;

EID: 2342570272     PISSN: 02693879     EISSN: None     Source Type: Journal    
DOI: 10.1002/bmc.303     Document Type: Article

References (12)

1. De Cock KJS, Delbeke FT, Van Eenoo P, Desmet N, Roels K and De Backer P. Detection and determination of anabolic steroids in nutritional supplements. Journal of Pharmaceutical and Biomedical Analysis 2001; 25: 843.
2. Eurachem. The Fitness for Purpose of Analytical Methods. A Laboratory Guide to Method Validation and Related Topics. Eurachem, 1998; 61.
3. Geyer H, Mareck-Engelke U, Reinhart U, Thevis M and Schänzer W. Positive dopingfälle mit norandrosteron durch verunreinigte nahrungsergänzungsmittel. Deutsche Zeitschrift fü r Sportmedizin 2000; 51, 11: 378.
4. Geyer H, Mareck-Engelke U, Wagner A and Schänzer W. Analysis of 'non-hormonal' nutritional supplements for prohormones. In Recent Advances in Doping Analysis, Vol. 9, Schänzer W, Gotzmann A and Mareck-Engelke U (eds). Sport und Buch Strauß: Koln, 2001: 63.
5. Geyer H, Parr MK, Mareck U, Reinhart U, Schrader Y and Schänzer W. Doping substances in nutritional supplements, results of the international IOC study: analysis of non-hormonal nutritional supplements for anabolic androgenic steroids. In Health and Doping Risks of Nutritional Supplements and Social Drugs Schänzer W, Delbeke F, Delogiannis A, Gmeiner G, Maughan R and Mester J (eds), Sport & Buch Strauss-Germany. 2002a.
6. Geyer H, Bredehöft M, Mareck U, Parr MK and Schänzer W. Hoge dosen des anabolikums metandienon in nahrungsergänzungsmittel. Dtsch. Apoth. Ztg. 2002b; 142(29): 50.
7. Gmeiner G. Metandienon in sportnahrung. Ostereichische Journal für Sportmedizin 2002; 2: 33.
8. International Olympic Committee. List of Prohibited Classes of Substances and Methods of Doping. International Olympic Committee, Medical Commission, Lausanne, 2001.
9. Maughan R. The scope of nutritional supplement use in sport. In Health and Doping Risks of Nutritional Supplements and Social Drugs Schänzer W, Delbeke F. Delogiannis A, Gmeiner G, Maughan R and Mester J (eds), Sport & Buch Strauss-Germany. 2002.
10. Schröder U. Health effects of nutritional supplements. In Health and Doping Risks of Nutritional Supplements and Social Drugs Schänzer W, Delbeke F, Delogiannis A, Gmeiner G, Maughan R and Mester J (eds), 2002.
11. Sobal J and Marquart LF. Vitamin mineral supplement use among athletes-A review of the literature. International Journal of Sport Nutrition 1994; 4: 320.
12. Verwaal W, van Bavel M, Boot A, Bravenboer J, de Goei F, Maas C and van der Putten A. De Ware(n) Chemicus 1996; 26: 25.