Simultaneous production of anthocyanin and triterpenoids in suspension cultures of Perilla frutescens

Enzyme and Microbial Technology

Volumn 34, Issue 7, 2004, Pages 651-656

  Wang, J W ^a   Xia, Z H ^a   Chu, J H ^a   Tan, R X ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Anthocyanin; Cell suspension culture; Elicitation; Labiatae; Perilla frutescens; Triterpenoids

Indexed keywords

ACETIC ACID; CELLS; ENZYMES; PRODUCTION; YEAST;

SINGLE CULTURE SYSTEM; SUSPENSION CULTURE;

CELL CULTURE;

2,4 DICHLOROPHENOXYACETIC ACID; 6 N BENZYLADENINE; ANTHOCYANIN; OLEANOLIC ACID; TORMENTIC ACID; TRITERPENOID; URSOLIC ACID;

ARTICLE; CELL LINE; CONTROLLED STUDY; CULTURE TECHNIQUE; DRUG SYNTHESIS; DRY WEIGHT; MURASHIGE AND SKOOG MEDIUM; NONHUMAN; PERILLA FRUTESCENS; QUANTITATIVE ANALYSIS; SUSPENSION CELL CULTURE; YEAST;

LAMIACEAE; PERILLA; PERILLA FRUTESCENS;

EID: 2342566925     PISSN: 01410229     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.enzmictec.2004.02.004     Document Type: Article

References (11)

1. Nakazawa T., Ohsawa K. Metabolites of orally administered Perilla frutescens extract in rats and humans. Biol Pharm Bull. 23:2000;122-127
2. Cai Y., Jiang J.G., Liu C.H., Kong L.D., Tan R.X. Composition and antifungal activity of essential oil from Perilla frutescens leaves. Int Pest Control. 44:2002;66-68
3. Chen J.H., Xia Z.H., Tan R.X. High-performance liquid chromatographic analysis of bioactive triterpenes in Perilla frustescens. J Pharm Biomed Anal. 32:2003;1175-1179
4. Murakami C., Ishijima K., Hirota M., Sakaguchi K., Yoshida H., Mizushina Y. Novel anti-inflammatory compounds from Rubus sieboldii, triterpenoids, are inhibitors of mammalian DNA polymerases. Biochim Biophys Acta. 1596:2002;193-200
5. Novotny L., Vachalkova A., Biggs D. Ursolic acid: an anti-tumorigenic and chemopreventive activity. Neoplasma. 48:2001;241-246
6. Zhong J.J., Yoshida M., Fujiyama K., Seki T., Yoshida T. Enhancement of anthocyanin production by suspended cultures of Perilla frutescens in a stirred bioreactor with internal light irradiation. J Ferment Bioeng. 75:1993;299-303
7. Wang J.W., Tan R.X. Artemisinin production in Artemisia annua hairy root cultures with improved growth by altering the nitrogen source in the medium. Biotechnol. Lett. 24:2002;1153-1156
8. Murashighe T., Skoog F. A revised medium for rapid growth and bioassays with tobacco tissue cultures. Physiol Plant. 15:1962;473-497
9. Chen H., Chen F. Effects of yeast elicitor on the growth and secondary metabolism of a high-tanshinone-producing line of the Ti transformed Salvia miltiorrhiza cells in suspension culture. Process Biochem. 35:2000;837-840
10. Zhong J., Seki T., Kinoshita S., Yoshida T. Effect of light irradiation on anthocyanin production by suspended culture of Perilla frutescens. Biotechnol Bioeng. 38:1991;653-658
11. van der Heijden R., Threlfall D.R., Verpoorte R., Whitehead I.M. Regulation and enzymology of pentacyclic triterpenoid phytoalexin biosynthesis in cell-suspension cultures of Tabernaemontana divaricata. Phytochemistry. 28:1989;2981-2988