Disposable integrated microfluidics with self-aligned planar microlenses

Sensors and Actuators, B: Chemical

Volumn 99, Issue 2-3, 2004, Pages 615-622

  Seo, Jeonggi ^a   Lee, Luke P ^a  

^a University of California at Berkeley   (United States)

Author keywords

Fluorescent biosensor; Integrated biophotonic chips; Integrated microfluidics; Planar microlens

Indexed keywords

ABERRATIONS; FLUORESCENCE; IMAGE ANALYSIS; LIGHT EMITTING DIODES; MICROELECTROMECHANICAL DEVICES; MOLDING; PHOTODIODES; SIGNAL TO NOISE RATIO; WAVEGUIDES;

FLUORESCENT BIOSENSOR; INTEGRATED BIOPHOTONIC CHIPS; INTEGRATED MICROFLUIDICS; PLANAR MICROLENS;

MICROLENSES;

EID: 2342540968     PISSN: 09254005     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.snb.2003.11.014     Document Type: Article

References (15)

1. Manz A., Graber N., Widmer H.M. Miniaturized total chemical analysis systems: a novel concept for chemical sensing. Sens. Actuators. B1:1990;244-248.
2. Nussbaum Ph., Völkel R., Herzig H.P., Eisner M., Haselbeck S. Design. Pure Appl. Opt. 6:1997;617-636.
3. Wendt J.R., Warren M.E., Sweatt W.C., Bailey C.G., Matzke C.M., Arnold D.W., Allerman A.A., Carter T.R., Asbill R.E., Samora S. Fabrication of high performance microlenses for an integrated capillary channel electrochromatograph with fluorescence detection. J. Vac. Sci. Technol. B. 17:1999;3252-3255.
4. Roulet J.-C., Volkel R., Herzig H.P., Verpoorte E., de Rooij N.F., Dandliker R. Microlens systems for fluorescence detection in chemical microsystems. Opt. Eng. 40:2001;814-821.
5. Hubner J., Mogensen K.B., Jorgensen A.M., Friis P., Telleman P., Kutter J.P. Integrated optical measurement system for fluorescence spectroscopy in microfluidic channels. Rev. Sci. Instrum. 72:2001;229-233.
6. Bryan B.G., Lytle F.E. On-chip absorption measurements using an integrated waveguide. Anal. Bioanal. Chem. 373:2002;519-525.
7. J.R. Webster, M.A. Burns, D.T. Burke, C.H. Mastrangelo, Electrophoresis system with integrated on-chip fluorescence detection, in: Proceedings of the IEEE Thirteenth Annual International Workshop on Micro Electro Mechanical Systems, Miyazaki, Japan, 23-27 January 2000, pp. 306-310.
8. E. Thrush, O. Levi, K. Wang, J.S. Harris, S.J. Smith, Integrated semiconductor fluorescent detection system for biochip and biomedical applications, in: Proceedings of the 2nd Annual International IEEE-EMBS Special Topic Conference Microtechnologies in Medicine and Biology, Madison, WI, USA, 2-4 May 2002, pp. 374-379.
9. Guifeng J., Attiya S., Ocvirk G., Lee W.E., Harrison D.J. Red diode laser induced fluorescence detection with a confocal microscope on a microchip for capillary electrophoresis. Biosens. Bioelectron. 14:2000;861-869.
10. Chabinyc M.L., Chiu D.T., McDonald J.C., Stroock A.D., Christian J.F., Karger A.M., Whitesides G.M. An integrated fluorescence detection system in poly(dimethylsiloxane) for microfluidic applications. Anal. Chem. 73:2001;4491-4498.
11. A. Paulus, S.J. Williams, A.P. Sassi, K. Pin, H. Tan, H.H. Hooper, Integrated capillary electrophoresis using glass and plastic chips for multiplexed DNA analysis, in: Proceedings of the SPIE 1998 Symposium on Microfluidic Devices and Systems, Santa Clara, CA, USA, 21-22 September 1998, pp. 94-103.
12. K. Kramer, Kwang W. Oh, C. H. Ahn, J.J. Bao, K.R. Wehmeyer, An optical MEMS-based fluorescence detection scheme with applications to capillary electrophoresis, in: Proceedings of the SPIE 1998 Symposium on Micromachining and Microfabrication, vol. 3515, Santa Clara, CA, 21-22 September 1998, pp. 76-85.
13. Roulet J.-C., Völkel R., Herzig H.P., Verpoorte E., de Rooij N.F., Dändliker R. Performance of an integrated microoptical system for fluorescence detection in microfluidic systems. Anal. Chem. 74:2002;3400-3407.
14. Private communication with Dow Corning Corporation.
15. R.P. Haugland, Handbook of Fluorescent Probes and Research Products, Molecular Probes Inc., Eugene, ninth ed., 2002, p. 177.