The circulating lymphocyte profiles in patients with discoid lupus erythematosus and systemic lupus erythematosus suggest a pathogenetic relationship

British Journal of Dermatology

Volumn 150, Issue 4, 2004, Pages 693-700

  Wouters, C H P ^a   Diegenant, C ^a   Ceuppens, J L ^a   Degreef, H ^a   Stevens, E A M ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

Discoid lupus erythematosus; Flow cytometry; Lymphocytes; Systemic lupus erythematosus

Indexed keywords

CD11B ANTIGEN; CD16 ANTIGEN; CD19 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD5 ANTIGEN; CD56 ANTIGEN; CD8 ANTIGEN; HLA DR ANTIGEN;

ADOLESCENT; ADULT; AGED; ARTICLE; B LYMPHOCYTE; CELLULAR IMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; DISCOID LUPUS ERYTHEMATOSUS; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IMMUNOPATHOLOGY; IMMUNOPHENOTYPING; IMMUNOREACTIVITY; LABORATORY TEST; LYMPHOCYTE; LYMPHOCYTOPENIA; MALE; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

ADOLESCENT; ADULT; AGED; ANTIGENS, CD; ANTIMALARIALS; B-LYMPHOCYTE SUBSETS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; FLOW CYTOMETRY; HLA-DR ANTIGENS; HUMANS; LUPUS ERYTHEMATOSUS, DISCOID; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYMPHOCYTES; MALE; MIDDLE AGED; T-LYMPHOCYTE SUBSETS;

EID: 2342536465     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0007-0963.2004.05883.x     Document Type: Article

References (33)

1. Watanabe T, Tsuchida T. Classification of lupus erythematosus based upon cutaneous manifestations. Dermatology 1995; 190: 277-83.
2. Sontheimer RD, Provost TT. Cutaneous manifestations of lupus erythematosus. In: Dubois' Lupus Erythematosus (Wallace DJ, Hahn BH, eds), 5th edn. Los Angeles: Williams & Wilkins, 1997; 569-623.
3. Gilliam JN, Sontheimer RD. Distinctive cutaneous subsets in the spectrum of lupus erythematosus. J Am Acad Dermatol 1981; 4: 471-5.
4. Rowell NR. Lupus erythematosus, scleroderma and dermatomyositis. The collagen or connective tissue diseases. In: Textbook of Dermatology (Rook A, Wilkinson DS, Ebling FJG, Champion RH, eds), 4th edn, Oxford: Blackwell Science, 1986; 1281-392.
5. Walport MJ. Systemic lupus erythematosus. In: Clinical Aspects of Immunology (Lachmann PJ, Peters DK, Rosen FS, Walport MJ, eds), 5th edn. Oxford: Blackwell Science, 1993; 1161-204.
6. Knop J, Bonsmann G, Kind P et al. Antigens of the major histocompatibility complex in patients with chronic discoid lupus erythematosus. Br J Dermatol 1990; 122: 723-8.
7. Rothe MJ, Kerdel FA. Review. Treatment of cutaneous lupus erythematosus. Lupus 1992; 1: 351-6.
8. Tebbe B, Mazur L, Stadler R, Orfanos CE. Immunohistochemical analysis of chronic discoid and subacute cutaneous lupus erythematosus; relation to immunopathological mechanisms. Br J Dermatol 1995; 132: 25-31.
9. Mori M, Pimpinelli N, Romagnoli P et al. Dendritic cells in cutaneous lupus erythematosus: a clue to the pathogenesis of lesions. Histopathology 1994; 24: 311-21.
10. Norris DA, Bennion SD, David-Bajar K. Pathomechanisms of cutaneous lupus erythematosus. In: Dubois' Lupus Erythematosus (Wallace DJ, Hahn BH, eds), 5th edn. Los Angeles: Williams & Wilkins, 1997; 549-67.
11. Rijlaarsdam JU, Nieboer C, De Vries E, Willemze R. Characterization of the dermal infiltrates in Jessner's lymphocytic infiltrate of the skin, polymorphous light eruption and cutaneous lupus erythematosus: differential diagnostic and pathogenetic aspects. J Cutan Pathol 1990; 17: 2-8.
12. Wangel AG, Johansson E, Ranki A. Polyclonal B cell activation and increased lymphocyte helper-suppressor ratios in discoid lupus erythematosus. Br J Dermatol 1984; 110: 665-9.
13. Kind P, Lipsky PE, Sontheimer RD. Circulating T- and B-cell abnormalities in cutaneous lupus erythematosus. J Invest Dermatol 1986; 86: 235-9.
14. Gilliam JN, Sontheimer RD. Skin manifestations of SLE. Clin Rheum Dis 1982; 8: 207-18.
15. Symmons DPM, Coppock JS, Bacon PA et al. Development and assessment of a computerized index of clinical disease activity in systemic lupus erythematosus. Q J Med 1988; 258: 927-37.
16. Stoll T, Stucki G, Malik J et al. Further validation of the BILAG disease activity index in patients with systemic lupus erythematosus. Ann Rheum Dis 1996; 55: 756-60.
17. Wouters C, Bossuyt X, Ceuppens JL, Stevens EAM. Comparative study of two cytofluorometric methods of analysis. J Immunol Meth 2000; 234: 89-98.
18. Hoshino T, Yamada A, Hoda J et al. Tissue-specific distribution and age-dependent increase of human CD11b+ T cells. J Immunol 1993; 151: 2237-46.
19. Nielsen HV, Christensen JP, Anderson EC et al. Expression of type 3 complement receptor on activated CD8+ T cells facilitates homing to inflammatory sites. J Immunol 1994; 153: 2021-8.
20. Lanier LL, Le AM, Givi CL et al. The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes. J Immunol 1986; 135: 4480-6.
21. van den Hove LE, Vandenberghe P, van Gool SW et al. Peripheral blood lymphocyte subset shifts in patients with untreated hematological tumors: evidence for systemic activation of the T cell compartment. Leuk Res 1998; 22: 175-84.
22. Cupps TR, Fauci A. Corticosteroid-mediated immunoregulation in man. Immunol Rev 1982; 6: 133-55.
23. Cupps TR, Edgar LC, Thomas CA, Fauci AS. Multiple mechanisms of B cell immunoregulation in man after administration of in vivo corticosteroids. J Immunol 1984; 132: 170-5.
24. McCune WJ. Cytotoxic drugs. In: Dubois' Lupus Erythematosus (Wallace DJ, Hahn BH, eds), 5th edn. Los Angeles: Williams & Wilkins, 1997; 1163-80.
25. Montero A, Jorfen M, Arpini R. Chronic cutaneous lupus erythematosus and subsequent infection with HIV1. Mater Med Pol 1992; 24: 21-31.
26. Kotzin BL, O'Dell JR. Systemic lupus erythematosus. In: Samter's Immunologic Diseases (Frank MM, Austen KF, Claman HN, Unanue EK, eds), 5th edn. Boston: Little, Brown, 1995; 667-97.
27. Schwartz R. Autoimmunity and autoimmune diseases. In: Fundamental Immunology (Paul WE, ed.), 3rd edn. New York: Raven Press, 1993; 1033-97.
28. Putterman C, Kuo P, Diamond B. The structure and derivation of antibodies and autoantibodies. In: Dubois' Lupus Erythematosus (Wallace DJ, Hahn BH, eds), 5th edn. Los Angeles: Williams & Wilkins, 1997; 383-96.
29. Horwitz DA, Stohl W, Gray JD. T lymphocytes, natural killer cells, cytokines and immune regulation. In: Dubois' Lupus Erythematosus (Wallace DJ, Hahn BH, eds), 5th edn, Los Angeles: Williams & Wilkins, 1997; 155-94.
30. Erkeller-Yuksel F, Hulstaart F, Hannet I et al. Lymphocyte subsets in a large cohort of patients with systemic lupus erythematosus. Lupus 1993; 2: 227-31.
31. Benedek RG. Historical background of discoid and systemic lupus erythematosus. In: Dubois' Lupus Erythematosus (Wallace DJ, Hahn BH, eds), 5th edn. Los Angeles: Williams & Wilkins, 1997; 3-16.
32. Ortaldo JR, Mason AT, O'Shea JJ, Perussia B. Receptor-induced death in human natural killer cells: involvement of CD16. J Exp Med 1995; 181: 339-44.
33. Erkeller-Yuksel F, Lydyard PM, Isenberg DA. Lack of NK cells in lupus patients with renal involvement. Lupus 1997; 6: 708-12.