Intrinsic primary afferent neurones of the digestive tract

Neurogastroenterology and Motility

Volumn 16, Issue SUPPL. 1, 2004, Pages 24-27

  Clerc, N ^a,c   Furness, J B ^b  

^a AIX MARSEILLE UNIVERSITY   (France)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c CNRS   (France)

Author keywords

Afferent neurones; Enteric nervous system; Inflammation; Ionic current

Indexed keywords

CALCIUM ION; CATION CHANNEL; POTASSIUM ION; VOLTAGE GATED SODIUM CHANNEL;

CALCIUM CURRENT; CONFERENCE PAPER; DIGESTIVE SYSTEM; HUMAN; INTESTINE INNERVATION; INTESTINE WALL; ION CURRENT; LARGE INTESTINE; MOTOR NERVE; MUSCLE SPINDLE AFFERENT NERVE; NERVE EXCITABILITY; POTASSIUM CURRENT; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SMALL INTESTINE; VASOMOTOR REFLEX;

ACTION POTENTIALS; ANIMALS; DIGESTIVE SYSTEM; ELECTROPHYSIOLOGY; ENTERIC NERVOUS SYSTEM; HUMANS; NEURONS, AFFERENT;

EID: 2342532320     PISSN: 13501925     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1743-3150.2004.00470.x     Document Type: Conference Paper

References (35)

1. Gershon MD, Kirchgessner AL, Wade PR. Intrinsic reflex pathways of the bowel wall. In: Taché Y, Wingate DL, Burks TF, eds. Innervation of the Gut: Pathophysiological Implications. Boca Raton: CRC Press, 1994: 275-88.
2. Wood JD. Physiology of the enteric nervous system. In: Johnson LR, ed. Physiology of the Gastrointestinal Tract. New York: Raven Press, 1994: 423-82.
3. Furness JB, Clerc N, Gola M, Kunze WAA, Fletcher EL. Identification of component neurons and organisation of enteric nerve circuits. In: Krammer HJ, Singer MV, eds. Neurogastroenterology - from Basics to Clinics. Dordrecht: Kluwer, 2000: 134-47.
4. Brookes SJH. Classes of enteric nerve cells in the guinea-pig small intestine. Anat Rec 2001; 262: 58-70.
5. Cervero F. Sensory innervation of the viscera: Peripheral basis of visceral pain. Physiol Rev 1994; 74: 95-138.
6. Sherrington CS. Cutaneous sensations. In: Schiffer EA, ed. Textbook of Physiology. Edinburgh: Pentland, 1900: 920-1001.
7. Eccles JC, Fatt P, Koketsu K. Cholinergic and inhibitory synapses in a pathway from motor-axon collaterals to motoneurons. J Physiol (Lond) 1954; 216: 524-62.
8. Lewis T. The Blood Vessels of the Human Skin and Their Responses. London: Shaw, 1927.
9. Holzer P, Livingston EH, Saria A, Guth PH. Sensory neurons mediate protective vasodilation in rat gastric mucosa. Am J Physiol 1991; 260: G363-G370.
10. Martin JH. Receptor physiology and sub-modality coding. In: Kandel ER, Schwartz JH, eds. Principles of Neural Science. New York: Elsevier, 1981: 157-69.
11. Kunze WAA, Bertrand PP, Furness JB, Bornstein JC. Influence of the mucosa on the excitability of myenteric neurons. Neuroscience 1997; 76: 619-34.
12. Gershon MD, Kirchgessner AL. Identification, characterization and projections of intrinsic primary afferent neurones of the submucosal plexus. J Autonom Nerv Syst 1991; 33: 185-7.
13. Kirchgessner AL, Tamir H, Gershon MD. Identification and stimulation by serotonin of intrinsic sensory neurons of the submucosal plexus of the guinea pig. J Neurosci 1992; 12: 235-48.
14. Bertrand PP, Kunze WAA, Bornstein JC, Furness JB, Smith ML. Analysis of the responses of myenteric neurons in the small intestine to chemical stimulation of the mucosa. Am J Physiol 1997; 273: G422-G435.
15. Kunze WAA, Clerc N, Furness JB, Gola M. The soma and neuntes of primary afferent neurons in the guinea-pig intestine respond differentially to deformation. J Physiol (Lond) 2000; 526: 375-85.
16. Kunze WAA, Furness JB, Bertrand PP, Bornstein JC. Intracellular recording from myenteric neurons of the guinea-pig ileum that respond to stretch. J Physiol (Lond) 1998; 506: 827-42.
17. Collins SM. The immunomodulation of enteric neuromuscular function: implications for motility and inflammatory disorders. Gastroenterology 1996; 111: 1683-99.
18. Lundgren O. Enteric nerves and diarrhoea. Pharmacol Toxicol 2002; 90: 109-20.
19. Clerc N, Gola M, Vogalis F, Furness JB. Controlling the excitability of IPANs: a possible route to therapeutics. Curr Opin Pharm 2002; 2: 657-64.
20. Rugiero F, Gola M, Kunze WAA, Reynaud J-C, Furness JB, Clerc N. Analysis of whole cell currents by patch clamp of guinea-pig myenteric neurones in intact ganglia. J Physiol (Lond) 2002; 538: 447-63.
21. North RA, Tokimasa T. Persistent calcium-sensitive potassium current and the resting properties of guinea-pig myenteric neurones. J Physiol (Lond) 1987; 386: 333-53.
22. v1.9 subunit in myenteric sensory neurons. J Neurosci 2003; 23: 2715-25.
23. Vogalis F, Harvey JR, Furness JB. TEA- and apamin-resistant KCa channels in guinea-pig myenteric neurons: slow AHP channels. J Physiol (Lond) 2002; 538: 421-33.
24. 2+-activated cation conductance in myenteric AH-neurons. Neuroscience 2002; 115: 375-93.
25. Wood JD, Mayer CJ. Intracellular study of electrical activity of Auerbach's plexus in guinea-pig small intestine. Pflügers Arch Eur J Physiol 1978; 374: 265-75.
26. Clerc N, Furness JB, Kunze WAA, Thomas EA, Bertrand PP. Long term effects of synaptic activation at low frequency on excitability of myenteric AH neurons. Neuroscience 1999; 90: 279-89.
27. Palmer JM, Wong Riley M, Sharkey KA. Functional alterations in jejunal myenteric neurons in nematode-infected guinea pigs. Am J Physiol 1998; 275: G922-G935.
28. Linden DR, Sharkey KA, Mawe GM. Enhanced excitability of myenteric AH neurones in the inflamed guinea-pig distal colon. J Physiol (Lond) 2003; 547: 589-601.
29. 2 in guinea pig colonic myenteric ganglia. Am J Physiol 2002; 283: G1388-G1397.
30. Sharkey KA, Mawe GM. Neuroimmune and epithelial interactions in intestinal inflammation. Curr Opin Pharm 2002; 2: 669-77.
31. Neal KR, Hebden J, Spiller R. Prevalence of gastrointestinal symptoms after bacterial gastroenteritis and risk factors for development of the irritable bowel syndrome. Br Med J 1997; 314: 779-92.
32. Roberts PJ, Morgan K, Miller R, Hunter JO, Middleton SJ. Neuronal COX-2 expression in human myenteric plexus in active inflammatory bowel disease. Gut 2001; 48: 468-72.
33. Barbara G, De Giorgio R, Deng Y, Vallance B, Blennerhassett P, Collins SM. Role of immunologic factors and cyclooxygenase 2 in persistent postinfective enteric muscle dysfunction in mice. Gastroenterology 2001; 120: 1729-36.
34. Dekkers JA, Akkermans LM, Kroese AB. Effects of the inflammatory mediator prostaglandin E2 on myenteric neurons in guinea pig ileum. Am J Physiol 1997; 272: G1451-G1456.
35. Furness JB, Kumano K, Larsson H, Murr E, Kunze WAA, Vogalis F. Sensitization of enteric reflexes in the rat colon in vitro. Autonom Neurosci 2002; 97: 19-25.