The safety of interleukin-1 receptor antagonist (anakinra) in the treatment of rheumatoid arthritis;Sicurezza e tollerabilità dell'antagonista del recettore dell'interleuchina-1 nel trattamento dell'artrite reumatoide

Reumatismo

Volumn 56, Issue 1 SUPPL. 1, 2004, Pages 74-79

  Riente, Lucrezia ^a,b  

^a UNIVERSITY OF PISA   (Italy)

^b UO di Reumatologia   (Italy)

Author keywords

Anakinra; Interleukin 1 receptor antagonist; Rheumatoid arthritis; Safety

Indexed keywords

AZATHIOPRINE; ETANERCEPT; GOLD SALT; HYDROXYCHLOROQUINE; INFLIXIMAB; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; LEFLUNOMIDE; METHOTREXATE; PENICILLAMINE; PLACEBO; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; SALAZOSULFAPYRIDINE;

ABDOMINAL PAIN; ABSCESS; ARTHRALGIA; BONE INFECTION; BURSITIS; CELLULITIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DIARRHEA; DISEASE EXACERBATION; DRUG SAFETY; DYSPNEA; FLU LIKE SYNDROME; GASTROINTESTINAL INFECTION; HEADACHE; HUMAN; IMMUNOTHERAPY; INFECTION; INFECTIOUS ARTHRITIS; INJECTION SITE; NAUSEA; OPPORTUNISTIC INFECTION; OSTEOMYELITIS; PNEUMONIA; RANDOMIZED CONTROLLED TRIAL; REVIEW; RHEUMATOID ARTHRITIS; SINUSITIS; TUBERCULOSIS; URINARY TRACT INFECTION;

ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; CLINICAL TRIALS; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; RECEPTORS, INTERLEUKIN-1; SIALOGLYCOPROTEINS;

EID: 2342523949     PISSN: 00487449     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (5)

1. AMGEN Inc. Anakinra FDA Briefing Information, August 16, 2001. Available at: http://www.fda.gov/ ohrms/dockets/ac/01/briefing/3779bI.htm
2. Bresnihan B, Alvaro-Gracia JM, Cobby M, Doherty M, Domljan Z, Emery P, et al. Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist. Arthritis Rheum 1998; 41: 2196-204.
3. Calabrese LH. Anakinra Treatment of Patients with Rheumatoid Arthritis. Ann Pharmacother 2002; 36: 1204-9.
4. Cohen S, Hurd E, Cush J, Schiff M, Weinblatt ME, Moreland WL, et al. Treatment of Rheumathoid Arthritis with Anakinra, a Recombinant Human Interleukin-1 Receptor Antagonist, in Combination with Methotrexate. Arthritis Rheum 2002; 46: 614-24.
5. Fleischmann R, Tesser J, Schechtman J, Modafferi D, Poulakos J, Bennett R, et al. A safety trial of anakinra, recombinant interleukin-1 receptor antagonist (IL-ra), in a large, placebo-controlled heterogenous population of patients with rheumatoid arthritis. Arthritis Rheum 2001; 44 (suppl. 9): S84.