Polysaccharides from Hibiscus sabdariffa flowers stimulate proliferation and differentiation of human keratinocytes

Planta Medica

Volumn 70, Issue 4, 2004, Pages 370-373

  Brunold, C ^a   Deters, A ^a   Knoepfel Sidler, F ^a   Hafner, J ^b   Muller B ^a   Hensel, A ^a,c  

^a University of Applied Sciences   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c H Wadenswil Univ of Applied Sci   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

INVOLUCRIN; POLYMER; POLYSACCHARIDE;

ARTICLE; CELL ACTIVITY; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; DRUG ISOLATION; FLOWER; FRACTIONATION; HIBISCUS; HIBISCUS SABDARIFFA; HUMAN; HUMAN CELL; ION EXCHANGE CHROMATOGRAPHY; KERATINOCYTE; MITOCHONDRION;

CELL DIVISION; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOWERS; HIBISCUS; HUMANS; KERATINOCYTES; PHYTOTHERAPY; PLANT EXTRACTS; POLYSACCHARIDES;

HIBISCUS; HIBISCUS SABDARIFFA;

EID: 2342517321     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-818952     Document Type: Article

References (13)

1. Müller BM, Franz G. Chemical structure and biological activity of polysaccharides from Hibiscus sabdariffa. Planta Med 1992; 58: 60-7
2. Dafallah AA, al-Mustafa Z. Investigation of the anti-inflammatory activity of Acacia nilotica and Hibiscus sabdariffa. American Journal of Chinese Medicine 1996; 24: 263-9
3. Sharaf A. The pharmacological characteristics of Hibiscus sabdariffa L. Planta Med 1962; 10: 48-52
4. Sharaf A, Gineidi A. The effect of Hibiscus sabdariffa on Mycobacterium tuberculosis. Planta Med 1963; 11: 109-12
5. Bonte F, Barre P, Pinguet P, Dusser I, Dumas M, Meybeck A. Simarouba amara extract increases human skin keratinocyte differentiation. J Ethnopharmacol 1996; 53: 65-74
6. Boukamp P, Petrussevska RT, Breitkreutz D, Hornung J, Markham A, Fusenig NE. Normal keratinization in a spontanously immortalized aneuploid human keratinocyte cell line. J Cell Biol 1988; 106: 761-71
7. Deters A, Schnetz E, Schmitt M, Hensel A. Effects of zinc histidine and zinc sulphate on normal human keratinocytes. Res Compl Class Nat Med 2003; 9: 316-22
8. Deters A, Dauer A, Schnetz E, Fartasch M, Hensel A. High-molecular products (proanthocyanidins and polysaccharides) from Hamamelis bark: influence on human keratinocyte proliferation and differentiation. Phytochemistry 2001; 58: 949-58
9. Porstmann T, Ternynck T, Avrameas S. Quantitation of 5-bromo-2- deoxyuridine incorporation into DNA: an enzyme immunoassay for the assessment of the lymphoid cell proliferative response. J Immun Meth 1985; 82: 169-79
10. Moosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immun Meth 1983; 65: 55-63
11. Amador E, Dorfman LE, Wacker WEC. Serum lactic dehydrogenase, an analytical assessment of current assays. Clin Chem 1963; 9: 391-5
12. Yabe T, Huang CC. Effect of lipoteichoic acid on proliferation and differentiation of keratinocytes. Otorhinolaryngol Head Neck Surg 1989; 101: 646-50
13. Deters A. Oligo- und Polysaccharide: Isolierung, Charakterisierung und Einfluss auf die Zellphysiologie humaner Keratinozyten. PhD thesis, University of Erlangen, Germany: 2003