The preparation of clinical grade 5-[i]iodo-2′-deoxyuridine and 5-[i]iodo-2′-deoxyuridine with high in vitro stability and the potential for early proliferation scintigraphy

Nuclear Medicine Communications

Volumn 25, Issue 5, 2004, Pages 461-468

  Schaffland, Andreas O ^a   Delaloye, Angelika Bischof ^a   Kosinski, Marek ^a   Dupertuis, Yves M ^b   Buchegger, Franz ^a,c  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b Divisions of Nutrition   (United States)

^c GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

Biodistribution; Fluorodeoxyuridine pretreatment; Iododeoxyuridine; Quality control

Indexed keywords

5 IODO 2' DEOXYURIDINE I 123; IDOXURIDINE DERIVATIVE; IDOXURIDINE I 125; TRACER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER DIAGNOSIS; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DRUG DEGRADATION; DRUG IDENTIFICATION; DRUG POTENCY; DRUG PURIFICATION; DRUG STABILITY; DRUG SYNTHESIS; DRUG UPTAKE; EXPERIMENTAL NEOPLASM; FEMALE; GOOD CLINICAL PRACTICE; GOOD LABORATORY PRACTICE; ISOTOPE LABELING; MOUSE; NONHUMAN; PH MEASUREMENT; QUALITY CONTROL; SCINTIGRAPHY; TISSUE DISTRIBUTION;

ANIMALS; CELL DIVISION; COLONIC NEOPLASMS; FEASIBILITY STUDIES; FEMALE; HUMANS; IDOXURIDINE; IODINE RADIOISOTOPES; ISOTOPE LABELING; METABOLIC CLEARANCE RATE; MICE; MICE, NUDE; NEOPLASM STAGING; ORGAN SPECIFICITY; RADIOPHARMACEUTICALS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TISSUE DISTRIBUTION;

EID: 2342512808     PISSN: 01433636     EISSN: 14735628     Source Type: Journal    
DOI: 10.1097/00006231-200405000-00006     Document Type: Article

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