Cinchona Alkaloid-Lewis Acid Catalyst Systems for Enantioselective Ketene-Aldehyde Cycloadditions

Journal of the American Chemical Society

Volumn 126, Issue 17, 2004, Pages 5352-5353

  Zhu, Cheng ^a   Shen, Xiaoqiang ^a   Nelson, Scott G ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE; ALKALOID; KETENE DERIVATIVE; LEWIS ACID;

ANALYTIC METHOD; ARTICLE; CATALYST; CINCHONA; CYCLOADDITION; ENANTIOSELECTIVITY; REACTION ANALYSIS; STEREOCHEMISTRY; TECHNOLOGY;

ACIDS; ALDEHYDES; CATALYSIS; CINCHONA ALKALOIDS; ETHYLENES; HYDROGEN-ION CONCENTRATION; KETONES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; STEREOISOMERISM;

EID: 2342504471     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0492900     Document Type: Article

References (22)

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21. For asymmetric ketene dimerizations catalyzed by O-silylated cinchona alkaloids, see ref 3c.
22. Slow addition of the acid chloride was employed to maintain relatively low ketene concentrations, thereby minimizing competing ketene dimerization.