Effects of propofol on respiratory mechanic and lung histology in normal rats

British Journal of Anaesthesia

Volumn 92, Issue 5, 2004, Pages 737-740

  Peratoner, A ^c   Nascimento, C S ^a   Santana, M C E ^a   Cadete, R A ^a   Negri, E M ^b   Gullo, A ^c   Rocco, P R M ^a   Zin, W A ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b A C CAMARGO CANCER CENTER   (Brazil)

^c UNIVERSITY OF TRIESTE   (Italy)

Author keywords

Anaesthesia; Anaesthetics i.v., propofol; Lung, bronchus, contraction index; Lung, respiratory mechanics

Indexed keywords

DIAZEPAM; PENTOBARBITAL; PROPOFOL;

ANESTHESIA INDUCTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREATHING MECHANICS; BRONCHODILATATION; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HISTOLOGY; INTERMETHOD COMPARISON; LUNG COMPLIANCE; LUNG FUNCTION; LUNG INFLATION; LUNG PRESSURE; LUNG VASCULAR RESISTANCE; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN; RESPIRATORY SYSTEM; RESPIRATORY TRACT PARAMETERS; SEDATION; THORAX WALL; VISCOELASTICITY;

EID: 2342480569     PISSN: 00070912     EISSN: None     Source Type: Journal    
DOI: 10.1093/bja/aeh128     Document Type: Article

References (9)

1. Wu RSC, Wu KC, Sum DCW, Bishop MJ. Comparative effects of thiopentone and propofol on respiratory resistance after tracheal intubation. Br J Anaesth 1996; 77: 735-8
2. Conti G, Dell'Utri D, Vilardi V et al. Propofol induces bronchodilatation in mechanically ventilated chronic obstructive pulmonary disease (COPD) patients. Acta Anaesthesiol Scand 1993; 37: 105-9
3. Ouedraogo N, Roux E, Forestier F, Rossetti M, Savineau J, Marthan R. Effects of intravenous anesthetics on normal and passively sensitized human isolated airway smooth muscle. Anesthesiology 1998; 88: 317-26
4. Yamakage M, Hirshman CA, Croxton TL. Inhibitory effects of thiopental, ketamine, and propofol on voltage-dependent calcium sup 2+ channels in porcine tracheal smooth muscle cells. Anesthesiology 1995; 83: 1274-82
5. Bates JHT, Rossi A, Milic-Emili J. Analysis of the behaviour of the respiratory system with constant inspiratory flow. J Appl Physiol 1985; 58: 1840-8
6. Weibel ER. Morphometry: stereological theory and practical methods. In: Gil J, ed. Models of Lung Disease: Microscopy and Structural Methods. New York: Marcel Dekker, 1990; 199-247
7. Reta GS, Riva JA, Piriz H, Medeiros AS, Rocco PRM, Zin WA. Effects of halothane on respiratory mechanics and lung histopathology in normal rats. Br J Anaesth 2000; 84: 372-7
8. Zin WA, Pengelly LD, Milic-Emili J. Single-breath method for measurement of respiratory mechanics in anesthetized animals. J Appl Physiol 1982; 52: 1266-71
9. Zin WA, Pengelly LD, Milic-Emili, J. Active impedance of respiratory system in anesthetized cats. J Appl Physiol 1982; 53: 149-57